GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10981873
Expression of MHC class II-associated invariant chain (Ii;CD74) in thymic epithelial neoplasms.
PMID:12782713
MIF signal transduction initiated by binding to CD74.
PMID:1448172
HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides.
PMID:17045821
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.
PMID:17357109
70-kDa heat shock proteins: specific interactions with HLA-DR molecules and their peptide fragments.
PMID:17435771
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment.
PMID:17567581
Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.
PMID:19423618
Increased CD74 expression in human atherosclerotic plaques: contribution to inflammatory responses in vascular cells.
PMID:19665027
A functional heteromeric MIF receptor formed by CD74 and CXCR4.
PMID:19849849
CD74 interacts with APP and suppresses the production of Abeta.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:20198449
Activation of CD74 inhibits migration of human mesenchymal stem cells.
PMID:20458337
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
PMID:22952837
Macrophage migration inhibitory factor inhibits the migration of cartilage end plate-derived stem cells by reacting with CD74.
PMID:24569872
Migration inhibitory factor enhances inflammation via CD74 in cartilage end plates with Modic type 1 changes on MRI.
PMID:24942581
CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.
PMID:25326458
Identification of chondroitin sulfate linkage region glycopeptides reveals prohormones as a novel class of proteoglycans.
PMID:29190904
Measurements of heterotypic associations between cluster of differentiation CD74 and CD44 in human breast cancer-derived cells.
PMID:30833792
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
PMID:32855215
MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses.
PMID:36213313
Mass spectrometric analysis of chondroitin sulfate-linked peptides.
PMID:37453717
Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.
PMID:7477400
The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.
Reactome:R-HSA-2130336
Initial proteolyis of Ii by aspartic proteases to lip22
Reactome:R-HSA-2130349
Generation of CLIP from lip10
Reactome:R-HSA-2130378
Transport of MHC II:Ii complex to plasma membrane
Reactome:R-HSA-2130393
Transport of MHC II:Ii complex along Golgi to TGN
Reactome:R-HSA-2130478
Interaction of invariant chain trimer and MHC II alpha beta dimer
Reactome:R-HSA-2130486
Uncoating of clathrin-coated vesicles and fusion with endosomes
Reactome:R-HSA-2130500
Insertion of MHC II:Ii complex in to the plasma membrane
Reactome:R-HSA-2130504
Cleavage of lip22 to lip10
Reactome:R-HSA-2130619
TGN-lysosomal vesicle coat assembly
Reactome:R-HSA-2130640
Recruitment of clathrin coated vesicle by Ii
Reactome:R-HSA-2130641
Translocation of TGN-lysosome vesicle to lysosome
Reactome:R-HSA-2130725
Internalization of MHC II:Ii clathrin coated vesicle
Reactome:R-HSA-2130731
Formation of COPII vesicle
Reactome:R-HSA-2213235
Trafficking of nonameric complex in the endocytic pathway
Reactome:R-HSA-2213236
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
Reactome:R-HSA-2213241
Formation of nonameric complex
Reactome:R-HSA-2213243
Fusion of COPII vesicle with Golgi complex
Reactome:R-HSA-2213246
Disassociation of CLIP from MHC II
Reactome:R-HSA-5676133
CD74 binds MIF
Reactome:R-HSA-8951498
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex
Reactome:R-HSA-8951500
Dissociation of CANX from nonameric complex
file:human/CD74/CD74-uniprot.txt
UniProtKB P04233 (HG2A_HUMAN) record