Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.
Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.
GABAA receptor-associated protein (GABARAP) induces apoptosis by interacting with DEAD (Asp-Glu-Ala-Asp/His) box polypeptide 47 (DDX 47).
A human protein-protein interaction network: a resource for annotating the proteome.
Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16.
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.
The TP53INP2 protein is required for autophagy in mammalian cells.
Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones.
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.
Nix is a selective autophagy receptor for mitochondrial clearance.
Nix, a receptor protein for mitophagy in mammals.
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Network organization of the human autophagy system.
Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth.
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.
TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death.
DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.
MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins.
Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites.
Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Phosphorylation of NBR1 by GSK3 modulates protein aggregation.
FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.
CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.
Regulation of endoplasmic reticulum turnover by selective autophagy.
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.
Architecture of the human interactome defines protein communities and disease networks.
Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
A reference map of the human binary protein interactome.
A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.
Cytoplasmic short linear motifs in ACE2 and integrin β(3) link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy.
The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Semisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3.
ER-phagy restrains inflammatory responses through its receptor UBAC2.
A TBK1-independent primordial function of STING in lysosomal biogenesis.
GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.
ATG16L1 complex transfers LC3 from ATG3 to PE
LC3 de-lipidation by ATG4
TBC1D25 (OATL1) binds ATG8 homologues
LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis.
Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.
UniProtKB entry O95166 (GABARAP)