Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

Combined Automated Annotation using Multiple IEA Methods

Retinoic acid activates Hoxd4 chromatin

Expression of Pax6 in anterior neural plate

Pax genes and their role in organogenesis.

Role of Pax6 in development of the cerebellar system.

Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development.

FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development.

Pax6 modulates the dorsoventral patterning of the mammalian telencephalon.

Further genetic analysis of two autosomal dominant mouse eye defects, Ccw and Pax6(coop).

Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye.

Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon.

Coordinated expression of Hoxa2, Hoxd1 and Pax6 in the developing diencephalon.

Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.

Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other.

Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors.

Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype.

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.

Distinct actions of Emx1, Emx2, and Pax6 in regulating the specification of areas in the developing neocortex.

The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo.

Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6.

Emx1, emx2 and pax6 in specification, regionalization and arealization of the cerebral cortex.

R-cadherin is a Pax6-regulated, growth-promoting cue for pioneer axons.

Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.

The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity.

Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1.

Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways.

Pax6 guides a relay of pioneer longitudinal axons in the embryonic mouse forebrain.

Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development.

Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex.

Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate.

Vax genes ventralize the embryonic eye.

Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.

Developmental and cellular factors underlying corneal epithelial dysgenesis in the Pax6+/- mouse model of aniridia.

A screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11.

Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.

Analysis of Pax6 expression using a BAC transgene reveals the presence of a paired-less isoform of Pax6 in the eye and olfactory bulb.

Heat shock protein 27 rescues motor neurons following nerve injury and preserves muscle function.

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.

Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube.

The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter.

Pax6 directly modulate Sox2 expression in the neural progenitor cells.

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.

Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system.

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis.

Differential regulation of telencephalic pallial-subpallial boundary patterning by Pax6 and Gsh2.

Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences.

The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation.

Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord.

The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex.

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.

AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells.

Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function.

Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cord.

Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development.

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.

Pancreas-enriched miRNA refines endocrine cell differentiation.

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism.

Paired related homeobox protein 1 is a regulator of stemness in adult neural stem/progenitor cells.

Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb.

Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation.

Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells.

The long non-coding RNA Paupar regulates the expression of both local and distal genes.

Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates.

MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.

Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon.

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

A visually guided swim assay for mouse models of human retinal disease recapitulates the multi-luminance mobility test in humans.

A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea.

Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain.

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling.

Pax6 influences the time and site of origin of glial precursors in the ventral neural tube.