ID   A0A2I0M3K7_COLLI        Unreviewed;       142 AA.
AC   A0A2I0M3K7;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-NOV-2024, entry version 13.
DE   SubName: Full=TruB pseudouridine (Psi) synthase family member 2 {ECO:0000313|EMBL:PKK24261.1};
GN   Name=TRUB2 {ECO:0000313|EMBL:PKK24261.1};
GN   ORFNames=A306_00006037 {ECO:0000313|EMBL:PKK24261.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Neoaves; Columbimorphae; Columbiformes;
OC   Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK24261.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK24261.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK24261.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase TruB family.
CC       {ECO:0000256|ARBA:ARBA00008999}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKK24261.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AKCR02000043; PKK24261.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0M3K7; -.
DR   STRING; 8932.A0A2I0M3K7; -.
DR   InParanoid; A0A2I0M3K7; -.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR002501; PsdUridine_synth_N.
DR   InterPro; IPR039048; Trub2.
DR   PANTHER; PTHR13195; PSEUDOURIDINE SYNTHASE-RELATED; 1.
DR   PANTHER; PTHR13195:SF0; PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL; 1.
DR   Pfam; PF01509; TruB_N; 1.
DR   SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT   DOMAIN          1..54
FT                   /note="Pseudouridine synthase II N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01509"
SQ   SEQUENCE   142 AA;  16236 MW;  B4EAF1B371475CC8 CRC64;
     MYSNIDMKTQ EAYELAVQGL IRPMEKSPPI ITGIRCLQFA PPEFQLEVHC LHETQQYLRK
     IVHEIGLELK SSAVCTQVRR TRDGVFTLDD ALLRTQWNLQ SIQKAIWDCQ LKVKTELEKT
     LGHQDKSLLQ TADAEMAHAA DS
//