CG46301 is a 1237-residue NOL4/NOL4L-family protein with a nucleolar-protein-4 helical domain. Its gene model incorporates the CG17341 and CG16879 names. A nuclear location is inferred by curated similarity annotation, while its molecular activity and the role of its extended sequence remain unresolved.
| GO Term | Evidence | Action | Reason |
|---|---|---|---|
| GO:0003674 molecular_function | ND GO_REF:0000015 | ACCEPT | Summary: Molecular activity is not established. Reason: NOL4/NOL4L family assignment and the helical domain are insufficient to specify an enzymatic or RNA-processing activity. Supporting Evidence: file:DROME/CG46301/CG46301-uniprot.txt DR InterPro; IPR056549; HTH_NOL4. file:DROME/CG46301/CG46301-uniprot.txt DR InterPro; IPR039788; NOL4/NOL4L. file:DROME/CG46301/CG46301-uniprot.txt FT DOMAIN 789..886 FT /note="Nucleolar protein 4 helical" FT /evidence="ECO:0000259|Pfam:PF23079" |
| GO:0005654 nucleoplasm | ISS GO_REF:0000024 | ACCEPT | Summary: Nucleoplasmic localization is a reasonable curated family inference. Reason: The NOL4/NOL4L assignment supports the existing ISS nuclear localization inference; there is no target-specific evidence contradicting it. The name nucleolar protein does not by itself establish nucleolar residence. Supporting Evidence: file:DROME/CG46301/CG46301-uniprot.txt DR InterPro; IPR056549; HTH_NOL4. file:DROME/CG46301/CG46301-uniprot.txt DR InterPro; IPR039788; NOL4/NOL4L. file:DROME/CG46301/CG46301-uniprot.txt FT DOMAIN 789..886 FT /note="Nucleolar protein 4 helical" FT /evidence="ECO:0000259|Pfam:PF23079" |
| GO:0008150 biological_process | ND GO_REF:0000015 | ACCEPT | Summary: Biological process remains unknown. Reason: The exact 1237-residue gene model contains NOL4-family sequence but no directly characterized biological process is established. Supporting Evidence: file:DROME/CG46301/CG46301-uniprot.txt DR InterPro; IPR056549; HTH_NOL4. file:DROME/CG46301/CG46301-uniprot.txt DR InterPro; IPR039788; NOL4/NOL4L. file:DROME/CG46301/CG46301-uniprot.txt FT DOMAIN 789..886 FT /note="Nucleolar protein 4 helical" FT /evidence="ECO:0000259|Pfam:PF23079" |
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