{
  "annotationScore": 2.0,
  "comments": [
    {
      "commentType": "SIMILARITY",
      "texts": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000256",
              "id": "ARBA00024195",
              "source": "ARBA"
            }
          ],
          "value": "Belongs to the peptidase S1 family. CLIP subfamily"
        }
      ]
    },
    {
      "commentType": "CAUTION",
      "texts": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000256",
              "id": "PRU00274",
              "source": "PROSITE-ProRule"
            }
          ],
          "value": "Lacks conserved residue(s) required for the propagation of feature annotation"
        }
      ]
    }
  ],
  "entryAudit": {
    "entryVersion": 168,
    "firstPublicDate": "2003-03-01",
    "lastAnnotationUpdateDate": "2026-09-02",
    "lastSequenceUpdateDate": "2010-11-30",
    "sequenceVersion": 2
  },
  "entryType": "UniProtKB unreviewed (TrEMBL)",
  "extraAttributes": {
    "countByCommentType": {
      "CAUTION": 1,
      "SIMILARITY": 1
    },
    "countByFeatureType": {
      "Chain": 1,
      "Domain": 1,
      "Signal": 1
    },
    "uniParcId": "UPI0001B78FEF"
  },
  "features": [
    {
      "description": "",
      "evidences": [
        {
          "evidenceCode": "ECO:0000256",
          "id": "SignalP",
          "source": "SAM"
        }
      ],
      "location": {
        "end": {
          "modifier": "EXACT",
          "value": 18
        },
        "start": {
          "modifier": "EXACT",
          "value": 1
        }
      },
      "type": "Signal"
    },
    {
      "description": "Peptidase S1 domain-containing protein",
      "evidences": [
        {
          "evidenceCode": "ECO:0000256",
          "id": "SignalP",
          "source": "SAM"
        }
      ],
      "featureId": "PRO_5004310266",
      "location": {
        "end": {
          "modifier": "EXACT",
          "value": 910
        },
        "start": {
          "modifier": "EXACT",
          "value": 19
        }
      },
      "type": "Chain"
    },
    {
      "description": "Peptidase S1",
      "evidences": [
        {
          "evidenceCode": "ECO:0000259",
          "id": "PS50240",
          "source": "PROSITE"
        }
      ],
      "location": {
        "end": {
          "modifier": "EXACT",
          "value": 340
        },
        "start": {
          "modifier": "EXACT",
          "value": 98
        }
      },
      "type": "Domain"
    }
  ],
  "genes": [
    {
      "geneName": {
        "evidences": [
          {
            "evidenceCode": "ECO:0000313",
            "id": "AAN10922.2",
            "source": "EMBL"
          }
        ],
        "value": "SPH208"
      },
      "orfNames": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "AAN10922.2",
              "source": "EMBL"
            },
            {
              "evidenceCode": "ECO:0000313",
              "id": "FBgn0028514",
              "source": "FlyBase"
            }
          ],
          "value": "CG4793"
        },
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "AAN10922.2",
              "source": "EMBL"
            }
          ],
          "value": "Dmel_CG4793"
        }
      ],
      "synonyms": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "AAN10922.2",
              "source": "EMBL"
            }
          ],
          "value": "BG:DS07486.3"
        },
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "AAN10922.2",
              "source": "EMBL"
            }
          ],
          "value": "cSPH128"
        },
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "AAN10922.2",
              "source": "EMBL"
            }
          ],
          "value": "Dmel\\CG4793"
        }
      ]
    }
  ],
  "keywords": [
    {
      "category": "PTM",
      "evidences": [
        {
          "evidenceCode": "ECO:0000256",
          "id": "ARBA00023157",
          "source": "ARBA"
        }
      ],
      "id": "KW-1015",
      "name": "Disulfide bond"
    },
    {
      "category": "Technical term",
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "id": "KW-1185",
      "name": "Reference proteome"
    },
    {
      "category": "Domain",
      "evidences": [
        {
          "evidenceCode": "ECO:0000256",
          "id": "SignalP",
          "source": "SAM"
        }
      ],
      "id": "KW-0732",
      "name": "Signal"
    }
  ],
  "organism": {
    "commonName": "Fruit fly",
    "evidences": [
      {
        "evidenceCode": "ECO:0000313",
        "id": "AAN10922.2",
        "source": "EMBL"
      },
      {
        "evidenceCode": "ECO:0000313",
        "id": "UP000000803",
        "source": "Proteomes"
      }
    ],
    "lineage": [
      "Eukaryota",
      "Metazoa",
      "Ecdysozoa",
      "Arthropoda",
      "Altocrustacea",
      "Allotriocarida",
      "Hexapoda",
      "Insecta",
      "Pterygota",
      "Neoptera",
      "Eumetabola",
      "Endopterygota",
      "Aparaglossata",
      "Panorpida",
      "Diptera",
      "Brachycera",
      "Muscomorpha",
      "Ephydroidea",
      "Drosophilidae",
      "Drosophila",
      "Sophophora"
    ],
    "scientificName": "Drosophila melanogaster",
    "taxonId": 7227
  },
  "primaryAccession": "Q8IP30",
  "proteinDescription": {
    "recommendedName": {
      "fullName": {
        "evidences": [
          {
            "evidenceCode": "ECO:0000259",
            "id": "PS50240",
            "source": "PROSITE"
          }
        ],
        "value": "Peptidase S1 domain-containing protein"
      }
    }
  },
  "proteinExistence": "3: Inferred from homology",
  "references": [
    {
      "citation": {
        "authors": [
          "Adams M.D.",
          "Celniker S.E.",
          "Holt R.A.",
          "Evans C.A.",
          "Gocayne J.D.",
          "Amanatides P.G.",
          "Scherer S.E.",
          "Li P.W.",
          "Hoskins R.A.",
          "Galle R.F.",
          "George R.A.",
          "Lewis S.E.",
          "Richards S.",
          "Ashburner M.",
          "Henderson S.N.",
          "Sutton G.G.",
          "Wortman J.R.",
          "Yandell M.D.",
          "Zhang Q.",
          "Chen L.X.",
          "Brandon R.C.",
          "Rogers Y.H.",
          "Blazej R.G.",
          "Champe M.",
          "Pfeiffer B.D.",
          "Wan K.H.",
          "Doyle C.",
          "Baxter E.G.",
          "Helt G.",
          "Nelson C.R.",
          "Gabor G.L.",
          "Abril J.F.",
          "Agbayani A.",
          "An H.J.",
          "Andrews-Pfannkoch C.",
          "Baldwin D.",
          "Ballew R.M.",
          "Basu A.",
          "Baxendale J.",
          "Bayraktaroglu L.",
          "Beasley E.M.",
          "Beeson K.Y.",
          "Benos P.V.",
          "Berman B.P.",
          "Bhandari D.",
          "Bolshakov S.",
          "Borkova D.",
          "Botchan M.R.",
          "Bouck J.",
          "Brokstein P.",
          "Brottier P.",
          "Burtis K.C.",
          "Busam D.A.",
          "Butler H.",
          "Cadieu E.",
          "Center A.",
          "Chandra I.",
          "Cherry J.M.",
          "Cawley S.",
          "Dahlke C.",
          "Davenport L.B.",
          "Davies P.",
          "de Pablos B.",
          "Delcher A.",
          "Deng Z.",
          "Mays A.D.",
          "Dew I.",
          "Dietz S.M.",
          "Dodson K.",
          "Doup L.E.",
          "Downes M.",
          "Dugan-Rocha S.",
          "Dunkov B.C.",
          "Dunn P.",
          "Durbin K.J.",
          "Evangelista C.C.",
          "Ferraz C.",
          "Ferriera S.",
          "Fleischmann W.",
          "Fosler C.",
          "Gabrielian A.E.",
          "Garg N.S.",
          "Gelbart W.M.",
          "Glasser K.",
          "Glodek A.",
          "Gong F.",
          "Gorrell J.H.",
          "Gu Z.",
          "Guan P.",
          "Harris M.",
          "Harris N.L.",
          "Harvey D.",
          "Heiman T.J.",
          "Hernandez J.R.",
          "Houck J.",
          "Hostin D.",
          "Houston K.A.",
          "Howland T.J.",
          "Wei M.H.",
          "Ibegwam C.",
          "Jalali M.",
          "Kalush F.",
          "Karpen G.H.",
          "Ke Z.",
          "Kennison J.A.",
          "Ketchum K.A.",
          "Kimmel B.E.",
          "Kodira C.D.",
          "Kraft C.",
          "Kravitz S.",
          "Kulp D.",
          "Lai Z.",
          "Lasko P.",
          "Lei Y.",
          "Levitsky A.A.",
          "Li J.",
          "Li Z.",
          "Liang Y.",
          "Lin X.",
          "Liu X.",
          "Mattei B.",
          "McIntosh T.C.",
          "McLeod M.P.",
          "McPherson D.",
          "Merkulov G.",
          "Milshina N.V.",
          "Mobarry C.",
          "Morris J.",
          "Moshrefi A.",
          "Mount S.M.",
          "Moy M.",
          "Murphy B.",
          "Murphy L.",
          "Muzny D.M.",
          "Nelson D.L.",
          "Nelson D.R.",
          "Nelson K.A.",
          "Nixon K.",
          "Nusskern D.R.",
          "Pacleb J.M.",
          "Palazzolo M.",
          "Pittman G.S.",
          "Pan S.",
          "Pollard J.",
          "Puri V.",
          "Reese M.G.",
          "Reinert K.",
          "Remington K.",
          "Saunders R.D.",
          "Scheeler F.",
          "Shen H.",
          "Shue B.C.",
          "Siden-Kiamos I.",
          "Simpson M.",
          "Skupski M.P.",
          "Smith T.",
          "Spier E.",
          "Spradling A.C.",
          "Stapleton M.",
          "Strong R.",
          "Sun E.",
          "Svirskas R.",
          "Tector C.",
          "Turner R.",
          "Venter E.",
          "Wang A.H.",
          "Wang X.",
          "Wang Z.Y.",
          "Wassarman D.A.",
          "Weinstock G.M.",
          "Weissenbach J.",
          "Williams S.M.",
          "WoodageT",
          "Worley K.C.",
          "Wu D.",
          "Yang S.",
          "Yao Q.A.",
          "Ye J.",
          "Yeh R.F.",
          "Zaveri J.S.",
          "Zhan M.",
          "Zhang G.",
          "Zhao Q.",
          "Zheng L.",
          "Zheng X.H.",
          "Zhong F.N.",
          "Zhong W.",
          "Zhou X.",
          "Zhu S.",
          "Zhu X.",
          "Smith H.O.",
          "Gibbs R.A.",
          "Myers E.W.",
          "Rubin G.M.",
          "Venter J.C."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "10731132"
          },
          {
            "database": "DOI",
            "id": "10.1126/science.287.5461.2185"
          }
        ],
        "citationType": "journal article",
        "firstPage": "2185",
        "id": "10731132",
        "journal": "Science",
        "lastPage": "2195",
        "publicationDate": "2000",
        "title": "The genome sequence of Drosophila melanogaster.",
        "volume": "287"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 1,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Celniker S.E.",
          "Wheeler D.A.",
          "Kronmiller B.",
          "Carlson J.W.",
          "Halpern A.",
          "Patel S.",
          "Adams M.",
          "Champe M.",
          "Dugan S.P.",
          "Frise E.",
          "Hodgson A.",
          "George R.A.",
          "Hoskins R.A.",
          "Laverty T.",
          "Muzny D.M.",
          "Nelson C.R.",
          "Pacleb J.M.",
          "Park S.",
          "Pfeiffer B.D.",
          "Richards S.",
          "Sodergren E.J.",
          "Svirskas R.",
          "Tabor P.E.",
          "Wan K.",
          "Stapleton M.",
          "Sutton G.G.",
          "Venter C.",
          "Weinstock G.",
          "Scherer S.E.",
          "Myers E.W.",
          "Gibbs R.A.",
          "Rubin G.M."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "12537568"
          }
        ],
        "citationType": "journal article",
        "firstPage": "RESEARCH0079",
        "id": "12537568",
        "journal": "Genome Biol.",
        "lastPage": "RESEARCH0079",
        "publicationDate": "2002",
        "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.",
        "volume": "3"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 2,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Misra S.",
          "Crosby M.A.",
          "Mungall C.J.",
          "Matthews B.B.",
          "Campbell K.S.",
          "Hradecky P.",
          "Huang Y.",
          "Kaminker J.S.",
          "Millburn G.H.",
          "Prochnik S.E.",
          "Smith C.D.",
          "Tupy J.L.",
          "Whitfied E.J.",
          "Bayraktaroglu L.",
          "Berman B.P.",
          "Bettencourt B.R.",
          "Celniker S.E.",
          "de Grey A.D.",
          "Drysdale R.A.",
          "Harris N.L.",
          "Richter J.",
          "Russo S.",
          "Schroeder A.J.",
          "Shu S.Q.",
          "Stapleton M.",
          "Yamada C.",
          "Ashburner M.",
          "Gelbart W.M.",
          "Rubin G.M.",
          "Lewis S.E."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "12537572"
          },
          {
            "database": "DOI",
            "id": "10.1186/gb-2002-3-12-research0083"
          }
        ],
        "citationType": "journal article",
        "firstPage": "RESEARCH0083.1",
        "id": "12537572",
        "journal": "Genome Biol.",
        "lastPage": "RESEARCH0083.22",
        "publicationDate": "2002",
        "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
        "volume": "3"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 3,
      "referencePositions": [
        "GENOME REANNOTATION"
      ]
    },
    {
      "citation": {
        "authors": [
          "Kaminker J.S.",
          "Bergman C.M.",
          "Kronmiller B.",
          "Carlson J.",
          "Svirskas R.",
          "Patel S.",
          "Frise E.",
          "Wheeler D.A.",
          "Lewis S.E.",
          "Rubin G.M.",
          "Ashburner M.",
          "Celniker S.E."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "12537573"
          }
        ],
        "citationType": "journal article",
        "firstPage": "RESEARCH0084.1",
        "id": "12537573",
        "journal": "Genome Biol.",
        "lastPage": "RESEARCH0084.20",
        "publicationDate": "2002",
        "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.",
        "volume": "3"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 4,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Hoskins R.A.",
          "Smith C.D.",
          "Carlson J.W.",
          "Carvalho A.B.",
          "Halpern A.",
          "Kaminker J.S.",
          "Kennedy C.",
          "Mungall C.J.",
          "Sullivan B.A.",
          "Sutton G.G.",
          "Yasuhara J.C.",
          "Wakimoto B.T.",
          "Myers E.W.",
          "Celniker S.E.",
          "Rubin G.M.",
          "Karpen G.H."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "12537574"
          }
        ],
        "citationType": "journal article",
        "firstPage": "RESEARCH0085",
        "id": "12537574",
        "journal": "Genome Biol.",
        "lastPage": "RESEARCH0085",
        "publicationDate": "2002",
        "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.",
        "volume": "3"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 5,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Quesneville H.",
          "Bergman C.M.",
          "Andrieu O.",
          "Autard D.",
          "Nouaud D.",
          "Ashburner M.",
          "Anxolabehere D."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "16110336"
          },
          {
            "database": "DOI",
            "id": "10.1371/journal.pcbi.0010022"
          }
        ],
        "citationType": "journal article",
        "firstPage": "166",
        "id": "16110336",
        "journal": "PLoS Comput. Biol.",
        "lastPage": "175",
        "publicationDate": "2005",
        "title": "Combined evidence annotation of transposable elements in genome sequences.",
        "volume": "1"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 6,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Smith C.D.",
          "Shu S.",
          "Mungall C.J.",
          "Karpen G.H."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "17569856"
          },
          {
            "database": "DOI",
            "id": "10.1126/science.1139815"
          }
        ],
        "citationType": "journal article",
        "firstPage": "1586",
        "id": "17569856",
        "journal": "Science",
        "lastPage": "1591",
        "publicationDate": "2007",
        "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.",
        "volume": "316"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 7,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Hoskins R.A.",
          "Carlson J.W.",
          "Kennedy C.",
          "Acevedo D.",
          "Evans-Holm M.",
          "Frise E.",
          "Wan K.H.",
          "Park S.",
          "Mendez-Lago M.",
          "Rossi F.",
          "Villasante A.",
          "Dimitri P.",
          "Karpen G.H.",
          "Celniker S.E."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "17569867"
          },
          {
            "database": "DOI",
            "id": "10.1126/science.1139816"
          }
        ],
        "citationType": "journal article",
        "firstPage": "1625",
        "id": "17569867",
        "journal": "Science",
        "lastPage": "1628",
        "publicationDate": "2007",
        "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.",
        "volume": "316"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 8,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authoringGroup": [
          "FlyBase Consortium"
        ],
        "authors": [
          "Matthews B.B.",
          "Dos Santos G.",
          "Crosby M.A.",
          "Emmert D.B.",
          "St Pierre S.E.",
          "Gramates L.S.",
          "Zhou P.",
          "Schroeder A.J.",
          "Falls K.",
          "Strelets V.",
          "Russo S.M.",
          "Gelbart W.M.",
          "null"
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "26109357"
          },
          {
            "database": "DOI",
            "id": ".1534/g3.115.018929"
          }
        ],
        "citationType": "journal article",
        "firstPage": "1721",
        "id": "26109357",
        "journal": "G3 (Bethesda)",
        "lastPage": "1736",
        "publicationDate": "2015",
        "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.",
        "volume": "5"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 9,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authoringGroup": [
          "FlyBase Consortium"
        ],
        "authors": [
          "Crosby M.A.",
          "Gramates L.S.",
          "Dos Santos G.",
          "Matthews B.B.",
          "St Pierre S.E.",
          "Zhou P.",
          "Schroeder A.J.",
          "Falls K.",
          "Emmert D.B.",
          "Russo S.M.",
          "Gelbart W.M.",
          "null"
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "26109356"
          },
          {
            "database": "DOI",
            "id": ".1534/g3.115.018937"
          }
        ],
        "citationType": "journal article",
        "firstPage": "1737",
        "id": "26109356",
        "journal": "G3 (Bethesda)",
        "lastPage": "1749",
        "publicationDate": "2015",
        "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.",
        "volume": "5"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 10,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    },
    {
      "citation": {
        "authors": [
          "Hoskins R.A.",
          "Carlson J.W.",
          "Wan K.H.",
          "Park S.",
          "Mendez I.",
          "Galle S.E.",
          "Booth B.W.",
          "Pfeiffer B.D.",
          "George R.A.",
          "Svirskas R.",
          "Krzywinski M.",
          "Schein J.",
          "Accardo M.C.",
          "Damia E.",
          "Messina G.",
          "Mendez-Lago M.",
          "de Pablos B.",
          "Demakova O.V.",
          "Andreyeva E.N.",
          "Boldyreva L.V.",
          "Marra M.",
          "Carvalho A.B.",
          "Dimitri P.",
          "Villasante A.",
          "Zhimulev I.F.",
          "Rubin G.M.",
          "Karpen G.H.",
          "Celniker S.E."
        ],
        "citationCrossReferences": [
          {
            "database": "PubMed",
            "id": "25589440"
          }
        ],
        "citationType": "journal article",
        "firstPage": "445",
        "id": "25589440",
        "journal": "Genome Res.",
        "lastPage": "458",
        "publicationDate": "2015",
        "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.",
        "volume": "25"
      },
      "evidences": [
        {
          "evidenceCode": "ECO:0000313",
          "id": "AAN10922.2",
          "source": "EMBL"
        },
        {
          "evidenceCode": "ECO:0000313",
          "id": "UP000000803",
          "source": "Proteomes"
        }
      ],
      "referenceComments": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000313",
              "id": "UP000000803",
              "source": "Proteomes"
            }
          ],
          "type": "STRAIN",
          "value": "Berkeley"
        }
      ],
      "referenceNumber": 11,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"
      ]
    }
  ],
  "sequence": {
    "crc64": "19B0218FD5DAEDF2",
    "length": 910,
    "md5": "B66B1C2932CD4D09F504CC7E450EABA5",
    "molWeight": 97522,
    "value": "MDRLSILLLVLGFSRIQALFCGGSMAKECVQRNRCRIGTETGRPIIDFRGLNNGNQGCESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSSTKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICLPPPNRNFIHNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGPYGKDFILDNSLICAGGEPGKDTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCGGPLPAAYTDVSQIRSWIDNCIQAEAVHYSPQLGNVGQSPAPLDRYIPNIGLETQNEVHSPVQGSLHNVVYQTGGVGYIRGMGQGTAFQGPVQVGELIPNEGTVSGGLVYDSNEIQKFNQGGIYIPHVGQGNSDNRYYPNPEIGAVPVGNPIPNEGNAFGGRGYDFNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNRYDLNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKELLKIGGNIPNVGQGNRGNIYDPNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNIYDPNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNRYDPNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNRYDLNPEIGHATFGATGTGMQGNNIDNPYKNNLGDRAENELERFPLENPNRDHVIRLSDFLITTPTPSAPIKLVIEKI"
  },
  "uniProtKBCrossReferences": [
    {
      "database": "EMBL",
      "id": "AE014134",
      "properties": [
        {
          "key": "ProteinId",
          "value": "AAN10922.2"
        },
        {
          "key": "Status",
          "value": "-"
        },
        {
          "key": "MoleculeType",
          "value": "Genomic_DNA"
        }
      ]
    },
    {
      "database": "RefSeq",
      "id": "NP_723941.2",
      "properties": [
        {
          "key": "NucleotideSequenceId",
          "value": "NM_165139.3"
        }
      ]
    },
    {
      "database": "AlphaFoldDB",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "SMR",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "FunCoup",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Number of interactors",
          "value": "8"
        }
      ]
    },
    {
      "database": "IntAct",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Interactions",
          "value": "1"
        }
      ]
    },
    {
      "database": "STRING",
      "id": "7227.FBpp0289839",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "MEROPS",
      "id": "S01.960",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "GlyGen",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "glycosylation",
          "value": "1 site"
        }
      ]
    },
    {
      "database": "PaxDb",
      "id": "7227-FBpp0289839",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "PeptideAtlas",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "DNASU",
      "id": "34941",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "GeneID",
      "id": "34941",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "KEGG",
      "id": "dme:Dmel_CG4793",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "UCSC",
      "id": "CG4793-RC",
      "properties": [
        {
          "key": "OrganismName",
          "value": "d. melanogaster"
        }
      ]
    },
    {
      "database": "AGR",
      "id": "FB:FBgn0028514",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "FlyBase",
      "id": "FBgn0028514",
      "properties": [
        {
          "key": "GeneName",
          "value": "CG4793"
        }
      ]
    },
    {
      "database": "VEuPathDB",
      "id": "VectorBase:FBgn0028514",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "eggNOG",
      "id": "KOG3627",
      "properties": [
        {
          "key": "ToxonomicScope",
          "value": "Eukaryota"
        }
      ]
    },
    {
      "database": "HOGENOM",
      "id": "CLU_319400_0_0_1",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "InParanoid",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "OrthoDB",
      "id": "6261922at2759",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "PhylomeDB",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "Description",
          "value": "-"
        }
      ]
    },
    {
      "database": "BioGRID-ORCS",
      "id": "34941",
      "properties": [
        {
          "key": "hits",
          "value": "0 hits in 1 CRISPR screen"
        }
      ]
    },
    {
      "database": "Proteomes",
      "id": "UP000000803",
      "properties": [
        {
          "key": "Component",
          "value": "Chromosome 2L"
        }
      ]
    },
    {
      "database": "Bgee",
      "id": "FBgn0028514",
      "properties": [
        {
          "key": "ExpressionPatterns",
          "value": "Expressed in arthropod fat body and 3 other cell types or tissues"
        }
      ]
    },
    {
      "database": "ExpressionAtlas",
      "id": "Q8IP30",
      "properties": [
        {
          "key": "ExpressionPatterns",
          "value": "baseline and differential"
        }
      ]
    },
    {
      "database": "GO",
      "evidences": [
        {
          "evidenceCode": "ECO:0000316",
          "id": "20168330",
          "source": "PubMed"
        }
      ],
      "id": "GO:0035208",
      "properties": [
        {
          "key": "GoTerm",
          "value": "P:positive regulation of hemocyte proliferation"
        },
        {
          "key": "GoEvidenceType",
          "value": "IGI:FlyBase"
        }
      ]
    },
    {
      "database": "GO",
      "id": "GO:0006508",
      "properties": [
        {
          "key": "GoTerm",
          "value": "P:proteolysis"
        },
        {
          "key": "GoEvidenceType",
          "value": "IBA:GO_Central"
        }
      ]
    },
    {
      "database": "CDD",
      "id": "cd00190",
      "properties": [
        {
          "key": "EntryName",
          "value": "Tryp_SPc"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    },
    {
      "database": "FunFam",
      "id": "2.40.10.10:FF:000002",
      "properties": [
        {
          "key": "EntryName",
          "value": "Transmembrane protease serine"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    },
    {
      "database": "Gene3D",
      "id": "2.40.10.10",
      "properties": [
        {
          "key": "EntryName",
          "value": "Trypsin-like serine proteases"
        },
        {
          "key": "MatchStatus",
          "value": "2"
        }
      ]
    },
    {
      "database": "InterPro",
      "id": "IPR009003",
      "properties": [
        {
          "key": "EntryName",
          "value": "Peptidase_S1_PA"
        }
      ]
    },
    {
      "database": "InterPro",
      "id": "IPR051487",
      "properties": [
        {
          "key": "EntryName",
          "value": "Ser/Thr_Proteases_Immune/Dev"
        }
      ]
    },
    {
      "database": "InterPro",
      "id": "IPR001254",
      "properties": [
        {
          "key": "EntryName",
          "value": "Trypsin_dom"
        }
      ]
    },
    {
      "database": "PANTHER",
      "id": "PTHR24256",
      "properties": [
        {
          "key": "EntryName",
          "value": "TRYPTASE-RELATED"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    },
    {
      "database": "Pfam",
      "id": "PF00089",
      "properties": [
        {
          "key": "EntryName",
          "value": "Trypsin"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    },
    {
      "database": "SMART",
      "id": "SM00020",
      "properties": [
        {
          "key": "EntryName",
          "value": "Tryp_SPc"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    },
    {
      "database": "SUPFAM",
      "id": "SSF50494",
      "properties": [
        {
          "key": "EntryName",
          "value": "Trypsin-like serine proteases"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    },
    {
      "database": "PROSITE",
      "id": "PS50240",
      "properties": [
        {
          "key": "EntryName",
          "value": "TRYPSIN_DOM"
        },
        {
          "key": "MatchStatus",
          "value": "1"
        }
      ]
    }
  ],
  "uniProtkbId": "Q8IP30_DROME"
}
