CG5611

UniProt ID: Q9VB17
Organism: Drosophila melanogaster
Review Status: DRAFT
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Gene Description

CG5611 is a 326-residue crotonase-superfamily protein containing an enoyl-CoA hydratase/isomerase-like domain. Its specific catalytic reaction, acyl-CoA substrate range and physiological role have not been established.

Existing Annotations Review

GO Term Evidence Action Reason
GO:0003674 molecular_function
ND
GO_REF:0000015 		ACCEPT
Summary: Retain the no-data placeholder while the exact enzymatic reaction, compartment and physiological process remain unestablished.
Reason: Retain the no-data placeholder while the exact enzymatic reaction, compartment and physiological process remain unestablished. The crotonase-like domain supports family identity but does not specify a substrate or distinguish its diverse hydratase/isomerase reactions.
Supporting Evidence:
file:DROME/CG5611/CG5611-uniprot.txt
DR Pfam; PF00378; ECH_1; 1.
GO:0005575 cellular_component
ND
GO_REF:0000015 		ACCEPT
Summary: Retain the no-data placeholder while the exact enzymatic reaction, compartment and physiological process remain unestablished.
Reason: Retain the no-data placeholder while the exact enzymatic reaction, compartment and physiological process remain unestablished. The crotonase-like domain supports family identity but does not specify a substrate or distinguish its diverse hydratase/isomerase reactions.
Supporting Evidence:
file:DROME/CG5611/CG5611-uniprot.txt
DR Pfam; PF00378; ECH_1; 1.
GO:0008150 biological_process
ND
GO_REF:0000015 		ACCEPT
Summary: Retain the no-data placeholder while the exact enzymatic reaction, compartment and physiological process remain unestablished.
Reason: Retain the no-data placeholder while the exact enzymatic reaction, compartment and physiological process remain unestablished. The crotonase-like domain supports family identity but does not specify a substrate or distinguish its diverse hydratase/isomerase reactions.
Supporting Evidence:
file:DROME/CG5611/CG5611-uniprot.txt
DR Pfam; PF00378; ECH_1; 1.

References

GO_REF:0000015
Use of the ND evidence code for Gene Ontology (GO) terms
file:DROME/CG5611/CG5611-uniprot.txt
DROME/CG5611/CG5611-uniprot.txt

External Prediction Reviews

These computational predictions are reviewed separately from the GOA annotation set used for this review. The assessments below are from this project and do not constitute official GO annotations or endorsement by GO/UniProt. They are not included in the existing annotation review above.

ProtNLM External predictions

View prediction review YAML · CG5611-protnlm-predictions-review.yaml · Review status: COMPLETE

The ProtNLM2 API snapshot retrieved 2026-09-08 contains no GO-term predictions for Q9VB17. The retained enoyl-CoA hydratase/isomerase-like domain supports a crotonase-family assignment, but the available evidence establishes neither a diagnostic subfamily nor a characterized ortholog with matching substrate specificity. Consequently, no specific fatty-acid oxidation or catalytic GO omission is confidently identified. The existing ND root annotations record this lack of functional evidence; they are not missing positive predictions. The separate tentative FUNCTION claim about fatty-acid oxidation remains UNC, as does the ancillary mitochondrial localization claim in the narrative review. This completed record assesses the absence of GO output; predictions is empty because no GO or EC prediction was emitted. The narrative judgments remain in the linked function review and are not scores assigned to the omission.

Source documents: genes/DROME/CG5611/CG5611-predictions-source.json · projects/PROTNLM_EVALUATION/fly-benchmark/manifest.json · genes/DROME/CG5611/CG5611-protnlm-function-review.md · genes/DROME/CG5611/CG5611-uniprot.txt

No GO/EC predictions in the reviewed source.

Deep Research

Falcon

(CG5611-deep-research-falcon.md)

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📚 Additional Documentation

Notes

(CG5611-notes.md)

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Protnlm Function Review

(CG5611-protnlm-function-review.md)

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📄 View Raw YAML

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