Serinc-PC is a native 458-residue SERINC-family multipass membrane protein. Its extensive transmembrane architecture supports a role in membrane biology, while the family name reflects historical associations with serine incorporation into lipids. The precise lipid substrate, transport mechanism and physiological role of this fly isoform are not directly established.
| GO Term | Evidence | Action | Reason |
|---|---|---|---|
| GO:0016020 membrane | IEA GO_REF:0000120 | ACCEPT | Summary: The native Serinc-PC product is an integral membrane protein. Reason: The exact M9PCT1 accession is mapped by FlyBase to a full native Serinc isoform and contains multiple hydrophobic transmembrane segments across its length. This independently supports the broad membrane annotation without relying on ARBA or assuming a specific lipid reaction. Supporting Evidence: file:DROME/Serinc/Serinc-uniprot.txt FT TRANSMEM 38..58 file:genes/DROME/Serinc/Serinc-flybase.txt Serinc-PC FBpp0302688 49.4 458 5.57 M9PCT1 NP_001261949 AGB94642 |
Loading supporting content…
Download this section (compressed HTML)Loading supporting content…
Download this section (compressed HTML)Loading supporting content…
Download this section (compressed HTML)