ID   B4MAQ2_DROVI            Unreviewed;      1238 AA.
AC   B4MAQ2;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   10-JUN-2026, entry version 95.
DE   SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDW66311.1};
DE   SubName: Full=Uncharacterized protein, isoform B {ECO:0000313|EMBL:KRF82632.1};
GN   Name=Dvir\GJ15622 {ECO:0000313|EMBL:EDW66311.1};
GN   ORFNames=Dvir_GJ15622 {ECO:0000313|EMBL:EDW66311.1};
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW66311.1, ECO:0000313|Proteomes:UP000008792};
RN   [1] {ECO:0000313|EMBL:EDW66311.1, ECO:0000313|Proteomes:UP000008792}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TSC#15010-1051.87 {ECO:0000313|EMBL:EDW66311.1}, and Tucson
RC   15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA   Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA   Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA   Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA   Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA   Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA   Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA   David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA   Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA   Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA   Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA   Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA   Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA   Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA   Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA   Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA   Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA   Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA   Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA   Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA   McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA   Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA   Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA   Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA   Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA   Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA   Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA   Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA   Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA   Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA   Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA   Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA   Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA   Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA   Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA   Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA   Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA   Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA   Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA   Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA   Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA   Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA   D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA   Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA   Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA   Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA   Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA   Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA   McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA   Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA   Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA   Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA   Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA   Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA   Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA   Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA   Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA   Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA   Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA   Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA   Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
RN   [2] {ECO:0000313|EMBL:EDW66311.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TSC#15010-1051.87 {ECO:0000313|EMBL:EDW66311.1};
RX   PubMed=18057021; DOI=10.1093/bioinformatics/btm542;
RA   Zimin A.V., Smith D.R., Sutton G., Yorke J.A.;
RT   "Assembly reconciliation.";
RL   Bioinformatics 24:42-45(2008).
RN   [3] {ECO:0000313|EMBL:EDW66311.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TSC#15010-1051.87 {ECO:0000313|EMBL:EDW66311.1};
RG   FlyBase;
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   EMBL; CH940655; EDW66311.1; -; Genomic_DNA.
DR   EMBL; CH940655; KRF82632.1; -; Genomic_DNA.
DR   STRING; 7244.B4MAQ2; -.
DR   KEGG; dvi:6634777; -.
DR   eggNOG; KOG2020; Eukaryota.
DR   HOGENOM; CLU_002828_0_0_1; -.
DR   OMA; IAKRSWG; -.
DR   OrthoDB; 2215036at2759; -.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR   GO; GO:0005634; C:nucleus; IEA:TreeGrafter.
DR   GO; GO:0042565; C:RNA nuclear export complex; IEA:TreeGrafter.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:TreeGrafter.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   GO; GO:0006405; P:RNA export from nucleus; IEA:TreeGrafter.
DR   FunFam; 1.25.10.10:FF:000588; exportin-5 isoform X2; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR045478; Exportin-5_C.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR045065; XPO1/5.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF3; EXPORTIN-5; 1.
DR   Pfam; PF19273; Exportin-5; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT   DOMAIN          34..100
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03810"
FT   DOMAIN          114..274
FT                   /note="Exportin-1/Importin-beta-like"
FT                   /evidence="ECO:0000259|Pfam:PF08389"
FT   DOMAIN          319..1193
FT                   /note="Exportin-5 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19273"
FT   REGION          1205..1238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1208..1230
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1238 AA;  139561 MW;  700D12156B1726D8 CRC64;
     MAQHGVTEAL AAELAKAVDL IMHPLTVQQA RLEAYTACER FKEESPLCAQ VGLYLASSVQ
     FNQQVRHFGL QLIEYTIKFK WNCITHEEKV YIKDNAIKML NMGVGPAEDR SLLHLKDALS
     RIIVEMIKRE WPQQWSDLLP ELSSACNNGE AQTELVLLVF LRLVEDVALL QTIESNQRRK
     DMYQALNNNM NDIFEFFLRL VEQHVNAFRE TTRLGNYHKA NAHSRVVEMV LLTLSGFVEW
     VSINHIMSSN GKLMHFLCIL LNDKAFQCNA AECLAQITNR KGQTKERKPL LQLYGEEPLR
     YIYTASQMPA DSVSAQAIEQ QHNFLKKLIQ VLNGMVQQLV ALWGKDEGTQ RPAHLDIMFE
     ILLLLVQHPS LTIAHGAALI WQLLLKHEGC SKDYLMVNNI PKLIHTIAPR IVKIPYPSSV
     PGQPDAALNS TEAYIRLEYD SEEEFAVYFF RCRTDFLEIF RLSTLVLPLI TYGYCEQWLQ
     LRLRHAQSER ESANMSCSVL DPIYLEWDAL VCVLDGVLSR ILLVAERPAV AGGLRLLEEC
     LKLETSNPLI YSILLSCISA LFVFLSMSSC QLTPNNCVAM SGVALLPRVL DKIFRALVLK
     PPNELEKVQQ KSAKNLRRHA ASLLVKLAHK YPLLLLPVFD QINNHVECLL KEPSSPYLCR
     MMRTTLQEAL ILISNHFCDF ERQTLFIEHI VQQKRSEWLS FGEAFKSPLE FMRFVGLDKP
     PVFDLDSDPS IVNRSRILDA LHVVLGVVKR CTWPDDPDRA QRGGFVIGCT DLGNPICRNP
     ATKHVVPLLS HVLSLMRVLN ELFRPEALAG LSEGYRNIHG MLEHEKKLLM GICAIPADPL
     DTTIKKEPTA FEKMQTFMTL VTEGCYHLMG SAGPSLGRDL YQLLGLSDAI ISNVFSCMDI
     IPDYRMRPII RVFFKPFVYS CPPTFYEPVL VPLFAHLTPL MCERLTRRWI YISSLYESGQ
     LNGEVNDTQE VLEDQLNRTL TREYLDVLKI ALVGGQIGAD HVNAVGGANV VAMENEEHSM
     DSAPQSRAAQ SALLSDIISD LGGKLLRNGL IGNYILMTLL KAIAWNDGMC NMKAVNIAAP
     VMRFLAAEQL MDENMAVSAF TAVLQGMQVH GQHEANQSGL ITLGVQFYEL LRPKFPVLSD
     VLQHIPSVNA ADVQKFDEKI SVAPVKGNKV DRAKKDIFKK LTAQLVGRSV NQLFRHEVQI
     ANLPPMQPVS QKNASTNTGD IMDSNQNANL SKLFRTEK
//