P05067 APP acts_upstream_of_or_within GO:0010468 "regulation of gene expression" IMP PMID:29274751
P05067 APP contributes_to GO:0048018 "receptor ligand activity" IDA PMID:33239400
P05067 APP enables GO:0004867 "serine-type endopeptidase inhibitor activity" IDA PMID:10652580
P05067 APP enables GO:0005102 "signaling receptor binding" IPI PMID:19849849
P05067 APP enables GO:0005515 "protein binding" IPI PMID:10049767
P05067 APP enables GO:0005515 "protein binding" IPI PMID:10081969
P05067 APP enables GO:0005515 "protein binding" IPI PMID:10677483
P05067 APP enables GO:0005515 "protein binding" IPI PMID:10681545
P05067 APP enables GO:0005515 "protein binding" IPI PMID:11238726
P05067 APP enables GO:0005515 "protein binding" IPI PMID:11278849
P05067 APP enables GO:0005515 "protein binding" IPI PMID:11297421
P05067 APP enables GO:0005515 "protein binding" IPI PMID:11724784
P05067 APP enables GO:0005515 "protein binding" IPI PMID:11877420
P05067 APP enables GO:0005515 "protein binding" IPI PMID:12054541
P05067 APP enables GO:0005515 "protein binding" IPI PMID:12901838
P05067 APP enables GO:0005515 "protein binding" IPI PMID:14527950
P05067 APP enables GO:0005515 "protein binding" IPI PMID:14557245
P05067 APP enables GO:0005515 "protein binding" IPI PMID:15896298
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16027166
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16049941
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16174740
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16286452
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16374483
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16407538
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16446437
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16480949
P05067 APP enables GO:0005515 "protein binding" IPI PMID:16554819
P05067 APP enables GO:0005515 "protein binding" IPI PMID:17112520
P05067 APP enables GO:0005515 "protein binding" IPI PMID:17709753
P05067 APP enables GO:0005515 "protein binding" IPI PMID:18026102
P05067 APP enables GO:0005515 "protein binding" IPI PMID:18468999
P05067 APP enables GO:0005515 "protein binding" IPI PMID:18509662
P05067 APP enables GO:0005515 "protein binding" IPI PMID:19849849
P05067 APP enables GO:0005515 "protein binding" IPI PMID:19901339
P05067 APP enables GO:0005515 "protein binding" IPI PMID:20195357
P05067 APP enables GO:0005515 "protein binding" IPI PMID:20811458
P05067 APP enables GO:0005515 "protein binding" IPI PMID:20817278
P05067 APP enables GO:0005515 "protein binding" IPI PMID:21163940
P05067 APP enables GO:0005515 "protein binding" IPI PMID:2119582
P05067 APP enables GO:0005515 "protein binding" IPI PMID:21293490
P05067 APP enables GO:0005515 "protein binding" IPI PMID:22730553
P05067 APP enables GO:0005515 "protein binding" IPI PMID:22801501
P05067 APP enables GO:0005515 "protein binding" IPI PMID:23585889
P05067 APP enables GO:0005515 "protein binding" IPI PMID:23973487
P05067 APP enables GO:0005515 "protein binding" IPI PMID:24028865
P05067 APP enables GO:0005515 "protein binding" IPI PMID:24284412
P05067 APP enables GO:0005515 "protein binding" IPI PMID:24336208
P05067 APP enables GO:0005515 "protein binding" IPI PMID:24867889
P05067 APP enables GO:0005515 "protein binding" IPI PMID:25241761
P05067 APP enables GO:0005515 "protein binding" IPI PMID:25959826
P05067 APP enables GO:0005515 "protein binding" IPI PMID:26496610
P05067 APP enables GO:0005515 "protein binding" IPI PMID:28720718
P05067 APP enables GO:0005515 "protein binding" IPI PMID:29423001
P05067 APP enables GO:0005515 "protein binding" IPI PMID:29578633
P05067 APP enables GO:0005515 "protein binding" IPI PMID:30086173
P05067 APP enables GO:0005515 "protein binding" IPI PMID:30538620
P05067 APP enables GO:0005515 "protein binding" IPI PMID:31413325
P05067 APP enables GO:0005515 "protein binding" IPI PMID:32814053
P05067 APP enables GO:0005515 "protein binding" IPI PMID:33961781
P05067 APP enables GO:0005515 "protein binding" IPI PMID:34446781
P05067 APP enables GO:0005515 "protein binding" IPI PMID:35063084
P05067 APP enables GO:0005515 "protein binding" IPI PMID:35914814
P05067 APP enables GO:0005515 "protein binding" IPI PMID:35922511
P05067 APP enables GO:0005515 "protein binding" IPI PMID:40205054
P05067 APP enables GO:0005515 "protein binding" IPI PMID:8626687
P05067 APP enables GO:0005515 "protein binding" IPI PMID:8855266
P05067 APP enables GO:0005515 "protein binding" IPI PMID:8887653
P05067 APP enables GO:0005515 "protein binding" IPI PMID:9223340
P05067 APP enables GO:0005515 "protein binding" IPI PMID:9338779
P05067 APP enables GO:0005515 "protein binding" IPI PMID:9461550
P05067 APP enables GO:0005515 "protein binding" IPI PMID:9774383
P05067 APP enables GO:0019899 "enzyme binding" IPI PMID:17112471
P05067 APP enables GO:0019899 "enzyme binding" IPI PMID:24499793
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:16286452
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:18805418
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:19549187
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:19754881
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:20573181
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:20818335
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:21113149
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:21205198
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:21320494
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:21527912
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:22200570
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:22584060
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:23103738
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:23353684
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:23416305
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:23551356
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:23603391
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:23907009
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:24065130
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:24720730
P05067 APP enables GO:0042802 "identical protein binding" IPI PMID:28882996
P05067 APP enables GO:0048018 "receptor ligand activity" IDA PMID:16174740
P05067 APP enables GO:0048018 "receptor ligand activity" IDA PMID:29518356
P05067 APP enables GO:0051425 "PTB domain binding" IPI PMID:12805363
P05067 APP enables GO:0120283 "protein serine/threonine kinase binding" IPI PMID:24305806
P05067 APP involved_in GO:0001774 "microglial cell activation" IGI PMID:15457210
P05067 APP involved_in GO:0001774 "microglial cell activation" IGI PMID:22406537
P05067 APP involved_in GO:0002265 "astrocyte activation involved in immune response" IGI PMID:23152628
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:15457210
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:19587288
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:20164328
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:20445063
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:21113149
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:24012003
P05067 APP involved_in GO:0007611 "learning or memory" IGI PMID:24052308
P05067 APP involved_in GO:0007611 "learning or memory" IMP PMID:11880515
P05067 APP involved_in GO:0007611 "learning or memory" IMP PMID:15457210
P05067 APP involved_in GO:0007612 "learning" IMP PMID:11140684
P05067 APP involved_in GO:0008285 "negative regulation of cell population proliferation" IDA PMID:22944668
P05067 APP involved_in GO:0010468 "regulation of gene expression" IGI PMID:21857966
P05067 APP involved_in GO:0010468 "regulation of gene expression" IGI PMID:26200696
P05067 APP involved_in GO:0010628 "positive regulation of gene expression" IGI PMID:22198949
P05067 APP involved_in GO:0010628 "positive regulation of gene expression" IGI PMID:27853422
P05067 APP involved_in GO:0010628 "positive regulation of gene expression" IGI PMID:28008308
P05067 APP involved_in GO:0010628 "positive regulation of gene expression" IGI PMID:29061364
P05067 APP involved_in GO:0010628 "positive regulation of gene expression" IMP PMID:15457210
P05067 APP involved_in GO:0010628 "positive regulation of gene expression" IMP PMID:23164821
P05067 APP involved_in GO:0010629 "negative regulation of gene expression" IGI PMID:22198949
P05067 APP involved_in GO:0010629 "negative regulation of gene expression" IGI PMID:27853422
P05067 APP involved_in GO:0010629 "negative regulation of gene expression" IGI PMID:28008308
P05067 APP involved_in GO:0010629 "negative regulation of gene expression" IGI PMID:29061364
P05067 APP involved_in GO:0014005 "microglia development" IGI PMID:22198949
P05067 APP involved_in GO:0032224 "positive regulation of synaptic transmission, cholinergic" IDA PMID:33239400
P05067 APP involved_in GO:0032722 "positive regulation of chemokine production" IGI PMID:22406537
P05067 APP involved_in GO:0032731 "positive regulation of interleukin-1 beta production" IGI PMID:22406537
P05067 APP involved_in GO:0032755 "positive regulation of interleukin-6 production" IGI PMID:22406537
P05067 APP involved_in GO:0032760 "positive regulation of tumor necrosis factor production" IGI PMID:22198949
P05067 APP involved_in GO:0032760 "positive regulation of tumor necrosis factor production" IGI PMID:22406537
P05067 APP involved_in GO:0032760 "positive regulation of tumor necrosis factor production" IGI PMID:29061364
P05067 APP involved_in GO:0045821 "positive regulation of glycolysis" IGI PMID:29061364
P05067 APP involved_in GO:0045944 "positive regulation of transcription by RNA polymerase II" IGI PMID:23921129
P05067 APP involved_in GO:0046330 "positive regulation of JNK cascade" IGI PMID:23921129
P05067 APP involved_in GO:0048143 "astrocyte activation" IGI PMID:15457210
P05067 APP involved_in GO:0048143 "astrocyte activation" IGI PMID:20445063
P05067 APP involved_in GO:0048169 "regulation of long-term neuronal synaptic plasticity" IGI PMID:23921129
P05067 APP involved_in GO:0050729 "positive regulation of inflammatory response" IMP PMID:29961672
P05067 APP involved_in GO:0050808 "synapse organization" IGI PMID:19587288
P05067 APP involved_in GO:0050808 "synapse organization" IGI PMID:24012003
P05067 APP involved_in GO:0050850 "positive regulation of calcium-mediated signaling" IGI PMID:22500019
P05067 APP involved_in GO:0051247 "positive regulation of protein metabolic process" IMP PMID:11404397
P05067 APP involved_in GO:0070374 "positive regulation of ERK1 and ERK2 cascade" IGI PMID:15457210
P05067 APP involved_in GO:0098815 "modulation of excitatory postsynaptic potential" IGI PMID:20974225
P05067 APP involved_in GO:0150003 "regulation of spontaneous synaptic transmission" IGI PMID:15457210
P05067 APP involved_in GO:1900272 "negative regulation of long-term synaptic potentiation" IGI PMID:15457210
P05067 APP involved_in GO:1900272 "negative regulation of long-term synaptic potentiation" IGI PMID:16636059
P05067 APP involved_in GO:1900273 "positive regulation of long-term synaptic potentiation" IGI PMID:20974225
P05067 APP involved_in GO:1901224 "positive regulation of non-canonical NF-kappaB signal transduction" IGI PMID:15457210
P05067 APP involved_in GO:1901224 "positive regulation of non-canonical NF-kappaB signal transduction" IMP PMID:29961672
P05067 APP involved_in GO:1904646 "cellular response to amyloid-beta" IDA PMID:29518356
P05067 APP involved_in GO:1904646 "cellular response to amyloid-beta" IGI PMID:23152628
P05067 APP involved_in GO:1905606 "regulation of presynapse assembly" IDA PMID:19726636
P05067 APP involved_in GO:1905606 "regulation of presynapse assembly" IMP PMID:19726636
P05067 APP involved_in GO:1905908 "positive regulation of amyloid fibril formation" IMP PMID:19660551
P05067 APP involved_in GO:1990000 "amyloid fibril formation" EXP PMID:26138908
P05067 APP involved_in GO:1990000 "amyloid fibril formation" EXP PMID:9737846
P05067 APP involved_in GO:1990000 "amyloid fibril formation" IMP PMID:25620700
P05067 APP involved_in GO:1990535 "neuron projection maintenance" IGI PMID:20445063
P05067 APP involved_in GO:2000406 "positive regulation of T cell migration" IMP PMID:19660551
P05067 APP is_active_in GO:0005576 "extracellular region" IDA PMID:29518356
P05067 APP is_active_in GO:0030425 "dendrite" IDA PMID:24012003
P05067 APP is_active_in GO:0031901 "early endosome membrane" IDA PMID:16174740
P05067 APP located_in GO:0005576 "extracellular region" EXP PMID:10656250
P05067 APP located_in GO:0005576 "extracellular region" EXP PMID:2649245
P05067 APP located_in GO:0005576 "extracellular region" HDA PMID:16502470
P05067 APP located_in GO:0005576 "extracellular region" IDA PMID:23921129
P05067 APP located_in GO:0005634 "nucleus" EXP PMID:11544248
P05067 APP located_in GO:0005641 "nuclear envelope lumen" IDA PMID:21989385
P05067 APP located_in GO:0005737 "cytoplasm" EXP PMID:11544248
P05067 APP located_in GO:0005737 "cytoplasm" IDA PMID:18509662
P05067 APP located_in GO:0005768 "endosome" IDA PMID:18353773
P05067 APP located_in GO:0005769 "early endosome" EXP PMID:20580937
P05067 APP located_in GO:0005769 "early endosome" IDA PMID:14527950
P05067 APP located_in GO:0005783 "endoplasmic reticulum" IDA PMID:14527950
P05067 APP located_in GO:0005794 "Golgi apparatus" IDA GO_REF:0000052
P05067 APP located_in GO:0005794 "Golgi apparatus" IDA PMID:14527950
P05067 APP located_in GO:0005794 "Golgi apparatus" IDA PMID:20427278
P05067 APP located_in GO:0005886 "plasma membrane" EXP PMID:10383380
P05067 APP located_in GO:0005886 "plasma membrane" EXP PMID:20580937
P05067 APP located_in GO:0005886 "plasma membrane" EXP PMID:2649245
P05067 APP located_in GO:0005886 "plasma membrane" IDA PMID:12805363
P05067 APP located_in GO:0005886 "plasma membrane" IDA PMID:20164328
P05067 APP located_in GO:0005886 "plasma membrane" IDA PMID:20427278
P05067 APP located_in GO:0005886 "plasma membrane" IDA PMID:28164773
P05067 APP located_in GO:0005886 "plasma membrane" IDA PMID:28855300
P05067 APP located_in GO:0009986 "cell surface" EXP PMID:11689470
P05067 APP located_in GO:0009986 "cell surface" EXP PMID:16154999
P05067 APP located_in GO:0009986 "cell surface" IDA PMID:18353773
P05067 APP located_in GO:0009986 "cell surface" IDA PMID:7593229
P05067 APP located_in GO:0016020 "membrane" EXP PMID:2900137
P05067 APP located_in GO:0031410 "cytoplasmic vesicle" EXP PMID:20580937
P05067 APP located_in GO:0031410 "cytoplasmic vesicle" EXP PMID:25122912
P05067 APP located_in GO:0043197 "dendritic spine" IDA PMID:11988176
P05067 APP located_in GO:0043198 "dendritic shaft" IDA PMID:11988176
P05067 APP located_in GO:0043204 "perikaryon" EXP PMID:10341243
P05067 APP located_in GO:0045121 "membrane raft" IDA PMID:24499793
P05067 APP located_in GO:0045202 "synapse" IDA PMID:11988176
P05067 APP located_in GO:0048471 "perinuclear region of cytoplasm" IDA PMID:20427278
P05067 APP located_in GO:0070062 "extracellular exosome" HDA PMID:19199708
P05067 APP part_of GO:0043235 "signaling receptor complex" IDA PMID:23382219
P05067 APP part_of GO:0106003 "amyloid-beta complex" IDA PMID:33239400
P05067-PRO_0000000093 APP NOT|colocalizes_with GO:0030425 "dendrite" IDA PMID:17251419
P05067-PRO_0000000093 APP NOT|colocalizes_with GO:0097060 "synaptic membrane" IDA PMID:17308309
P05067-PRO_0000000093 APP colocalizes_with GO:0005764 "lysosome" IDA PMID:23152628
P05067-PRO_0000000093 APP enables GO:0005109 "frizzled binding" IPI PMID:18234671
P05067-PRO_0000000093 APP enables GO:0005178 "integrin binding" IDA PMID:21126803
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:10673326
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:11756426
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:15615705
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:17051221
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:17116874
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:18806802
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:22179788
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:22528093
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:23585889
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:24931469
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:25643321
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:25897080
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:26618561
P05067-PRO_0000000093 APP enables GO:0005515 "protein binding" IPI PMID:30158114
P05067-PRO_0000000093 APP enables GO:0034185 "apolipoprotein binding" IPI PMID:22138302
P05067-PRO_0000000093 APP enables GO:0034185 "apolipoprotein binding" IPI PMID:9211985
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:17116874
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:18059284
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:18483195
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:18499799
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:19304802
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:19458258
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:19706468
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:19706519
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:19841277
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:20133839
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:22036569
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:22179788
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:25543257
P05067-PRO_0000000093 APP enables GO:0042802 "identical protein binding" IPI PMID:30158114
P05067-PRO_0000000093 APP enables GO:0042803 "protein homodimerization activity" IPI PMID:15447668
P05067-PRO_0000000093 APP enables GO:0042803 "protein homodimerization activity" IPI PMID:22179788
P05067-PRO_0000000093 APP enables GO:0043395 "heparan sulfate proteoglycan binding" IMP PMID:21289173
P05067-PRO_0000000093 APP enables GO:0046982 "protein heterodimerization activity" IPI PMID:18568035
P05067-PRO_0000000093 APP enables GO:0046982 "protein heterodimerization activity" IPI PMID:19660551
P05067-PRO_0000000093 APP enables GO:0050786 "RAGE receptor binding" IPI PMID:22406537
P05067-PRO_0000000093 APP enables GO:0051087 "protein-folding chaperone binding" IPI PMID:23106396
P05067-PRO_0000000093 APP enables GO:0051087 "protein-folding chaperone binding" IPI PMID:9228033
P05067-PRO_0000000093 APP involved_in GO:0010628 "positive regulation of gene expression" IDA PMID:26006083
P05067-PRO_0000000093 APP involved_in GO:0010628 "positive regulation of gene expression" IGI PMID:23164821
P05067-PRO_0000000093 APP involved_in GO:0010628 "positive regulation of gene expression" IMP PMID:27853422
P05067-PRO_0000000093 APP involved_in GO:0010629 "negative regulation of gene expression" IDA PMID:26006083
P05067-PRO_0000000093 APP involved_in GO:0010629 "negative regulation of gene expression" IGI PMID:18234671
P05067-PRO_0000000093 APP involved_in GO:0032729 "positive regulation of type II interferon production" IGI PMID:17255335
P05067-PRO_0000000093 APP involved_in GO:0032760 "positive regulation of tumor necrosis factor production" IGI PMID:12808450
P05067-PRO_0000000093 APP involved_in GO:0043525 "positive regulation of neuron apoptotic process" IGI PMID:23164821
P05067-PRO_0000000093 APP involved_in GO:0051260 "protein homooligomerization" IPI PMID:15447668
P05067-PRO_0000000093 APP involved_in GO:0051260 "protein homooligomerization" IPI PMID:18602473
P05067-PRO_0000000093 APP involved_in GO:0051260 "protein homooligomerization" IPI PMID:22179788
P05067-PRO_0000000093 APP involved_in GO:0051262 "protein tetramerization" IPI PMID:19660551
P05067-PRO_0000000093 APP involved_in GO:0055096 "low-density lipoprotein particle mediated signaling" IDA PMID:26005850
P05067-PRO_0000000093 APP involved_in GO:0070206 "protein trimerization" IPI PMID:19660551
P05067-PRO_0000000093 APP involved_in GO:0090090 "negative regulation of canonical Wnt signaling pathway" IDA PMID:18234671
P05067-PRO_0000000093 APP involved_in GO:1900181 "negative regulation of protein localization to nucleus" IGI PMID:18234671
P05067-PRO_0000000093 APP involved_in GO:1900272 "negative regulation of long-term synaptic potentiation" IDA PMID:18568035
P05067-PRO_0000000093 APP involved_in GO:1900454 "positive regulation of long-term synaptic depression" IDA PMID:18568035
P05067-PRO_0000000093 APP involved_in GO:1901224 "positive regulation of non-canonical NF-kappaB signal transduction" IDA PMID:22406537
P05067-PRO_0000000093 APP involved_in GO:1902951 "negative regulation of dendritic spine maintenance" IDA PMID:18568035
P05067-PRO_0000000093 APP involved_in GO:1902993 "positive regulation of amyloid precursor protein catabolic process" IGI PMID:22406537
P05067-PRO_0000000093 APP involved_in GO:1903523 "negative regulation of blood circulation" IGI PMID:12808450
P05067-PRO_0000000093 APP involved_in GO:1904472 "positive regulation of endothelin production" IGI PMID:12808450
P05067-PRO_0000000093 APP involved_in GO:1904591 "positive regulation of protein import" IDA PMID:23164821
P05067-PRO_0000000093 APP located_in GO:0005576 "extracellular region" IDA PMID:26005850
P05067-PRO_0000000093 APP located_in GO:0005576 "extracellular region" IMP PMID:23640054
P05067-PRO_0000000093 APP located_in GO:0005739 "mitochondrion" IDA PMID:23525105
P05067-PRO_0000000093 APP located_in GO:0005769 "early endosome" IDA PMID:26005850
P05067-PRO_0000000093 APP located_in GO:0070381 "endosome to plasma membrane transport vesicle" IDA PMID:26005850
P05067-PRO_0000000093 APP part_of GO:0032991 "protein-containing complex" IDA PMID:9228033
P05067-PRO_0000000093 APP part_of GO:0032991 "protein-containing complex" IPI PMID:18568035
P05067-PRO_0000000093 APP part_of GO:0034361 "very-low-density lipoprotein particle" IPI PMID:9211985
P05067-PRO_0000000093 APP part_of GO:0034362 "low-density lipoprotein particle" IPI PMID:9211985
P05067-PRO_0000000093 APP part_of GO:0034363 "intermediate-density lipoprotein particle" IDA PMID:22138302
P05067-PRO_0000000093 APP part_of GO:0034363 "intermediate-density lipoprotein particle" IPI PMID:9211985
P05067-PRO_0000000093 APP part_of GO:0034364 "high-density lipoprotein particle" IDA PMID:22138302
P05067-PRO_0000000093 APP part_of GO:0034364 "high-density lipoprotein particle" IPI PMID:9211985
P05067-PRO_0000000093 APP part_of GO:0106003 "amyloid-beta complex" IMP PMID:23640054
P05067-PRO_0000000093 APP part_of GO:0106003 "amyloid-beta complex" IPI PMID:18568035
P05067-PRO_0000000093 APP part_of GO:0106003 "amyloid-beta complex" IPI PMID:22036569
P05067-PRO_0000000093 APP part_of GO:0106003 "amyloid-beta complex" IPI PMID:22179788
P05067-PRO_0000000093 APP part_of GO:1990777 "lipoprotein particle" IDA PMID:22138302
P05067-PRO_0000000096 APP involved_in GO:0001878 "response to yeast" IMP PMID:20209079
P05067-PRO_0000000096 APP involved_in GO:0019731 "antibacterial humoral response" IDA PMID:20209079
P05067-PRO_0000000096 APP involved_in GO:0019732 "antifungal humoral response" IMP PMID:20209079
P05067-PRO_0000000096 APP involved_in GO:0045087 "innate immune response" IMP PMID:20209079
P05067-PRO_0000000096 APP involved_in GO:0050829 "defense response to Gram-negative bacterium" IDA PMID:20209079
P05067-PRO_0000000096 APP involved_in GO:0050830 "defense response to Gram-positive bacterium" IDA PMID:20209079
P05067-PRO_0000000096 APP involved_in GO:0061844 "antimicrobial humoral immune response mediated by antimicrobial peptide" IMP PMID:20209079
P08592 App NOT|located_in GO:0008021 "synaptic vesicle" IDA PMID:8987743
P08592 App enables GO:0008270 "zinc ion binding" EXP PMID:22225807
P08592 App enables GO:0016504 "peptidase activator activity" IDA PMID:12493564
P08592 App enables GO:0070851 "growth factor receptor binding" IPI PMID:19334058
P08592 App involved_in GO:0006816 "calcium ion transport" IDA PMID:18291427
P08592 App involved_in GO:0007611 "learning or memory" IEP PMID:35317728
P08592 App involved_in GO:0010288 "response to lead ion" IEP PMID:16230335
P08592 App involved_in GO:0010288 "response to lead ion" IEP PMID:29908845
P08592 App involved_in GO:0036269 "swimming behavior" IEP PMID:33574912
P08592 App involved_in GO:0043523 "regulation of neuron apoptotic process" IEP PMID:33574912
P08592 App involved_in GO:0045471 "response to ethanol" IEP PMID:24595328
P08592 App involved_in GO:0051247 "positive regulation of protein metabolic process" IDA PMID:11404397
P08592 App involved_in GO:0070555 "response to interleukin-1" IDA PMID:20395292
P08592 App involved_in GO:0071280 "cellular response to copper ion" IEP PMID:18583042
P08592 App involved_in GO:0071287 "cellular response to manganese ion" IEP PMID:18583042
P08592 App involved_in GO:0071320 "cellular response to cAMP" IEP PMID:9144253
P08592 App involved_in GO:0071874 "cellular response to norepinephrine stimulus" IMP PMID:9144253
P08592 App involved_in GO:0110088 "hippocampal neuron apoptotic process" IDA PMID:18291427
P08592 App involved_in GO:1990090 "cellular response to nerve growth factor stimulus" IEP PMID:10821917
P08592 App involved_in GO:1990418 "response to insulin-like growth factor stimulus" IEP PMID:33574912
P08592 App is_active_in GO:0098992 "neuronal dense core vesicle" IDA PMID:29577889
P08592 App located_in GO:0005576 "extracellular region" IDA PMID:14615045
P08592 App located_in GO:0005737 "cytoplasm" IDA PMID:24595328
P08592 App located_in GO:0009986 "cell surface" IDA PMID:29914798
P08592 App located_in GO:0009986 "cell surface" IDA PMID:8987743
P08592 App located_in GO:0030424 "axon" IDA PMID:8987743
P08592 App located_in GO:0030426 "growth cone" IDA PMID:12843239
P08592 App located_in GO:0043195 "terminal bouton" HDA PMID:24876496
P08592 App located_in GO:0043204 "perikaryon" EXP PMID:10341243
P08592 App located_in GO:0044304 "main axon" IDA PMID:12843239
P08592 App located_in GO:0097449 "astrocyte projection" IDA PMID:8097074
P08592 App located_in GO:1990761 "growth cone lamellipodium" IDA PMID:12843239
P08592 App located_in GO:1990812 "growth cone filopodium" IDA PMID:12843239
P12023 App acts_upstream_of_or_within GO:0001967 "suckling behavior" IGI PMID:9461064
P12023 App acts_upstream_of_or_within GO:0006417 "regulation of translation" IDA PMID:16314516
P12023 App acts_upstream_of_or_within GO:0006468 "protein phosphorylation" IMP PMID:16025111
P12023 App acts_upstream_of_or_within GO:0006878 "intracellular copper ion homeostasis" IGI PMID:15447675
P12023 App acts_upstream_of_or_within GO:0006878 "intracellular copper ion homeostasis" IMP PMID:10526140
P12023 App acts_upstream_of_or_within GO:0006897 "endocytosis" IMP PMID:16025111
P12023 App acts_upstream_of_or_within GO:0006979 "response to oxidative stress" IGI PMID:16478525
P12023 App acts_upstream_of_or_within GO:0007409 "axonogenesis" IMP PMID:9390996
P12023 App acts_upstream_of_or_within GO:0007617 "mating behavior" IGI PMID:9461064
P12023 App acts_upstream_of_or_within GO:0007626 "locomotory behavior" IGI PMID:9461064
P12023 App acts_upstream_of_or_within GO:0008088 "axo-dendritic transport" IGI PMID:20829454
P12023 App acts_upstream_of_or_within GO:0008088 "axo-dendritic transport" IMP PMID:11740561
P12023 App acts_upstream_of_or_within GO:0008203 "cholesterol metabolic process" IGI PMID:17920016
P12023 App acts_upstream_of_or_within GO:0008203 "cholesterol metabolic process" IMP PMID:17920016
P12023 App acts_upstream_of_or_within GO:0008344 "adult locomotory behavior" IMP PMID:10188929
P12023 App acts_upstream_of_or_within GO:0008344 "adult locomotory behavior" IMP PMID:7758106
P12023 App acts_upstream_of_or_within GO:0008344 "adult locomotory behavior" IMP PMID:8001115
P12023 App acts_upstream_of_or_within GO:0008344 "adult locomotory behavior" IMP PMID:9754878
P12023 App acts_upstream_of_or_within GO:0008542 "visual learning" IMP PMID:10338291
P12023 App acts_upstream_of_or_within GO:0010467 "gene expression" IMP PMID:30902970
P12023 App acts_upstream_of_or_within GO:0010468 "regulation of gene expression" IDA PMID:12074840
P12023 App acts_upstream_of_or_within GO:0010971 "positive regulation of G2/M transition of mitotic cell cycle" IMP PMID:15561424
P12023 App acts_upstream_of_or_within GO:0016199 "axon midline choice point recognition" IMP PMID:8001115
P12023 App acts_upstream_of_or_within GO:0016322 "neuron remodeling" IMP PMID:10219973
P12023 App acts_upstream_of_or_within GO:0016358 "dendrite development" IGI PMID:15689559
P12023 App acts_upstream_of_or_within GO:0016358 "dendrite development" IMP PMID:10188929
P12023 App acts_upstream_of_or_within GO:0016358 "dendrite development" IMP PMID:9390996
P12023 App acts_upstream_of_or_within GO:0030198 "extracellular matrix organization" IGI PMID:15385965
P12023 App acts_upstream_of_or_within GO:0030900 "forebrain development" IGI PMID:15385965
P12023 App acts_upstream_of_or_within GO:0030900 "forebrain development" IMP PMID:10200318
P12023 App acts_upstream_of_or_within GO:0030900 "forebrain development" IMP PMID:8001115
P12023 App acts_upstream_of_or_within GO:0031175 "neuron projection development" IDA PMID:8083748
P12023 App acts_upstream_of_or_within GO:0035235 "ionotropic glutamate receptor signaling pathway" IMP PMID:16025111
P12023 App acts_upstream_of_or_within GO:0040014 "regulation of multicellular organism growth" IMP PMID:9754878
P12023 App acts_upstream_of_or_within GO:0045665 "negative regulation of neuron differentiation" IDA PMID:18278038
P12023 App acts_upstream_of_or_within GO:0045665 "negative regulation of neuron differentiation" IGI PMID:18278038
P12023 App acts_upstream_of_or_within GO:0045931 "positive regulation of mitotic cell cycle" IMP PMID:15561424
P12023 App acts_upstream_of_or_within GO:0045944 "positive regulation of transcription by RNA polymerase II" IDA PMID:15944124
P12023 App acts_upstream_of_or_within GO:0045944 "positive regulation of transcription by RNA polymerase II" IGI PMID:15944124
P12023 App acts_upstream_of_or_within GO:0048669 "collateral sprouting in absence of injury" IGI PMID:15689559
P12023 App acts_upstream_of_or_within GO:0050803 "regulation of synapse structure or activity" IMP PMID:10219973
P12023 App acts_upstream_of_or_within GO:0050885 "neuromuscular process controlling balance" IGI PMID:9461064
P12023 App acts_upstream_of_or_within GO:0050890 "cognition" IDA PMID:25592972
P12023 App acts_upstream_of_or_within GO:0051124 "synaptic assembly at neuromuscular junction" IGI PMID:15689559
P12023 App acts_upstream_of_or_within GO:0051402 "neuron apoptotic process" IGI PMID:16478525
P12023 App acts_upstream_of_or_within GO:0051563 "smooth endoplasmic reticulum calcium ion homeostasis" IGI PMID:12431992
P12023 App acts_upstream_of_or_within GO:0180011 "cytosolic mRNA polyadenylation" IDA PMID:16314516
P12023 App acts_upstream_of_or_within GO:1905607 "negative regulation of presynapse assembly" IMP PMID:30902970
P12023 App enables GO:0000978 "RNA polymerase II cis-regulatory region sequence-specific DNA binding" IDA PMID:15944124
P12023 App enables GO:0005515 "protein binding" IPI PMID:10460257
P12023 App enables GO:0005515 "protein binding" IPI PMID:11517249
P12023 App enables GO:0005515 "protein binding" IPI PMID:11877420
P12023 App enables GO:0005515 "protein binding" IPI PMID:12826668
P12023 App enables GO:0005515 "protein binding" IPI PMID:16193067
P12023 App enables GO:0005515 "protein binding" IPI PMID:16227578
P12023 App enables GO:0005515 "protein binding" IPI PMID:16227582
P12023 App enables GO:0005515 "protein binding" IPI PMID:16314516
P12023 App enables GO:0005515 "protein binding" IPI PMID:16407538
P12023 App enables GO:0005515 "protein binding" IPI PMID:17121854
P12023 App enables GO:0005515 "protein binding" IPI PMID:17727637
P12023 App enables GO:0005515 "protein binding" IPI PMID:17934213
P12023 App enables GO:0005515 "protein binding" IPI PMID:18278038
P12023 App enables GO:0005515 "protein binding" IPI PMID:18650440
P12023 App enables GO:0005515 "protein binding" IPI PMID:20497468
P12023 App enables GO:0005515 "protein binding" IPI PMID:20573181
P12023 App enables GO:0005515 "protein binding" IPI PMID:20637285
P12023 App enables GO:0005515 "protein binding" IPI PMID:20817278
P12023 App enables GO:0005515 "protein binding" IPI PMID:20925061
P12023 App enables GO:0005515 "protein binding" IPI PMID:21084623
P12023 App enables GO:0005515 "protein binding" IPI PMID:21368882
P12023 App enables GO:0005515 "protein binding" IPI PMID:21795536
P12023 App enables GO:0005515 "protein binding" IPI PMID:22685302
P12023 App enables GO:0005515 "protein binding" IPI PMID:23283322
P12023 App enables GO:0005515 "protein binding" IPI PMID:23585889
P12023 App enables GO:0005515 "protein binding" IPI PMID:23719799
P12023 App enables GO:0005515 "protein binding" IPI PMID:24305806
P12023 App enables GO:0005515 "protein binding" IPI PMID:26960425
P12023 App enables GO:0005515 "protein binding" IPI PMID:27460146
P12023 App enables GO:0005515 "protein binding" IPI PMID:30902970
P12023 App enables GO:0019901 "protein kinase binding" IPI PMID:24305806
P12023 App enables GO:0019904 "protein domain specific binding" IDA PMID:30902970
P12023 App enables GO:0030546 "signaling receptor activator activity" IDA PMID:11316806
P12023 App is_active_in GO:0009986 "cell surface" IDA PMID:30902970
P12023 App is_active_in GO:0030424 "axon" IMP PMID:30902970
P12023 App is_active_in GO:0048786 "presynaptic active zone" IDA PMID:23815291
P12023 App is_active_in GO:0048786 "presynaptic active zone" IEP PMID:23815291
P12023 App is_active_in GO:0097708 "intracellular vesicle" IDA PMID:30902970
P12023 App located_in GO:0005634 "nucleus" EXP PMID:28720718
P12023 App located_in GO:0005737 "cytoplasm" IDA PMID:10845772
P12023 App located_in GO:0005769 "early endosome" EXP PMID:26260791
P12023 App located_in GO:0005769 "early endosome" IDA PMID:25592972
P12023 App located_in GO:0005794 "Golgi apparatus" IDA PMID:16018997
P12023 App located_in GO:0005798 "Golgi-associated vesicle" IDA PMID:23931995
P12023 App located_in GO:0005886 "plasma membrane" EXP PMID:26260791
P12023 App located_in GO:0005886 "plasma membrane" IDA PMID:15009636
P12023 App located_in GO:0005911 "cell-cell junction" IDA PMID:23793062
P12023 App located_in GO:0008021 "synaptic vesicle" IDA PMID:25438880
P12023 App located_in GO:0009986 "cell surface" IDA PMID:16227578
P12023 App located_in GO:0016020 "membrane" IDA PMID:10845772
P12023 App located_in GO:0016020 "membrane" IDA PMID:12927782
P12023 App located_in GO:0016020 "membrane" IDA PMID:15886206
P12023 App located_in GO:0016020 "membrane" IDA PMID:9535056
P12023 App located_in GO:0030134 "COPII-coated ER to Golgi transport vesicle" IDA PMID:19966784
P12023 App located_in GO:0030424 "axon" IDA PMID:11740561
P12023 App located_in GO:0030424 "axon" IDA PMID:15745965
P12023 App located_in GO:0030424 "axon" IDA PMID:25631124
P12023 App located_in GO:0031410 "cytoplasmic vesicle" IDA PMID:11740561
P12023 App located_in GO:0031410 "cytoplasmic vesicle" IDA PMID:15745965
P12023 App located_in GO:0031594 "neuromuscular junction" IDA PMID:10845772
P12023 App located_in GO:0035253 "ciliary rootlet" IDA PMID:16018997
P12023 App located_in GO:0043005 "neuron projection" IDA PMID:16301330
P12023 App located_in GO:0045177 "apical part of cell" IDA PMID:15561424
P12023 App located_in GO:0048471 "perinuclear region of cytoplasm" IDA PMID:8207383
P12023 App located_in GO:0051233 "spindle midzone" IDA PMID:15561424
P12023 App located_in GO:0055037 "recycling endosome" IDA PMID:23931995
P12023-PRO_0000000118 App enables GO:0005515 "protein binding" IPI PMID:19242475
P12023-PRO_0000000118 App enables GO:0005515 "protein binding" IPI PMID:20133875
P12023-PRO_0000000118 App enables GO:0005515 "protein binding" IPI PMID:21113149
P12023-PRO_0000000118 App involved_in GO:0043408 "regulation of MAPK cascade" IDA PMID:15190117
P12023-PRO_0000000118 App involved_in GO:0045666 "positive regulation of neuron differentiation" IDA PMID:15190117
P12023-PRO_0000000118 App involved_in GO:1900272 "negative regulation of long-term synaptic potentiation" IDA PMID:18568035
P12023-PRO_0000000119 App enables GO:0050750 "low-density lipoprotein particle receptor binding" IPI PMID:22383525
P12023-PRO_0000000119 App involved_in GO:0032760 "positive regulation of tumor necrosis factor production" IGI PMID:12808450
P12023-PRO_0000000119 App involved_in GO:1900272 "negative regulation of long-term synaptic potentiation" IDA PMID:18568035
P12023-PRO_0000000119 App involved_in GO:1903523 "negative regulation of blood circulation" IGI PMID:12808450
P12023-PRO_0000000119 App involved_in GO:1904472 "positive regulation of endothelin production" IGI PMID:12808450