ID A0A9L0IJ72_EQUAS Unreviewed; 481 AA. AC A0A9L0IJ72; DT 13-SEP-2023, integrated into UniProtKB/TrEMBL. DT 13-SEP-2023, sequence version 1. DT 02-SEP-2026, entry version 14. DE RecName: Full=Nuclear distribution protein nudE-like 1 {ECO:0000256|ARBA:ARBA00017587}; GN Name=NDEL1 {ECO:0000313|Ensembl:ENSEASP00005040207.1}; OS Equus asinus (Donkey) (Equus africanus asinus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. OX NCBI_TaxID=9793 {ECO:0000313|Ensembl:ENSEASP00005040207.1, ECO:0000313|Proteomes:UP000694387}; RN [1] {ECO:0000313|Ensembl:ENSEASP00005040207.1, ECO:0000313|Proteomes:UP000694387} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=33293529; RA Wang, C., Li, H., Guo, Y., Huang, J., Sun, Y., Min, J., Wang, J., Fang, X., RA Zhao, Z., Wang, S., Zhang, Y., Liu, Q., Jiang, Q., Wang, X., Guo, Y., Yang, RA C., Wang, Y., Tian, F., Zhuang, G., Fan, Y., Gao, Q., Li, Y., Ju, Z., Li, RA J., Li, R., Hou, M., Yang, G., Liu, G., Liu, W., Guo, J., Pan, S., Fan, G., RA Zhang, W., Zhang, R., Yu, J., Zhang, X., Yin, Q., Ji, C., Jin, Y., Yue, G., RA Liu, M., Xu, J., Liu, S., Jordana, J., Noce, A., Amills, M., Wu, D.D., Li, RA S., Zhou, X. and Zhong, J.; RT "Donkey genomes provide new insights into domestication and selection for RT coat color."; RL Nat. Commun. 11:6014-6014(2020). RN [2] {ECO:0000313|Ensembl:ENSEASP00005040207.1} RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2026) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore CC {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton, microtubule CC organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. CC Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. CC -!- SIMILARITY: Belongs to the nudE family. CC {ECO:0000256|ARBA:ARBA00007429}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; A0A9L0IJ72; -. DR Ensembl; ENSEAST00005052565.1; ENSEASP00005040207.1; ENSEASG00005019855.2. DR GeneTree; ENSGT00390000000111; -. DR Proteomes; UP000694387; Chromosome 13. DR GO; GO:0043203; C:axon hillock; IEA:Ensembl. DR GO; GO:0031252; C:cell leading edge; IEA:Ensembl. DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell. DR GO; GO:0005871; C:kinesin complex; IEA:TreeGrafter. DR GO; GO:0000776; C:kinetochore; IEA:Ensembl. DR GO; GO:0060053; C:neurofilament cytoskeleton; IEA:Ensembl. DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell. DR GO; GO:0008021; C:synaptic vesicle; IEA:Ensembl. DR GO; GO:0043014; F:alpha-tubulin binding; IEA:Ensembl. DR GO; GO:0048487; F:beta-tubulin binding; IEA:Ensembl. DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl. DR GO; GO:0008017; F:microtubule binding; IEA:Ensembl. DR GO; GO:0051642; P:centrosome localization; IEA:TreeGrafter. DR GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl. DR GO; GO:0007059; P:chromosome segregation; IEA:Ensembl. DR GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:TreeGrafter. DR GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl. DR GO; GO:0032418; P:lysosome localization; IEA:Ensembl. DR GO; GO:0007020; P:microtubule nucleation; IEA:TreeGrafter. DR GO; GO:0007100; P:mitotic centrosome separation; IEA:TreeGrafter. DR GO; GO:1900029; P:positive regulation of ruffle assembly; IEA:Ensembl. DR GO; GO:0033157; P:regulation of intracellular protein transport; IEA:Ensembl. DR GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl. DR GO; GO:0047496; P:vesicle transport along microtubule; IEA:TreeGrafter. DR Gene3D; 6.10.250.1080; -; 1. DR InterPro; IPR033494; NUDE. DR InterPro; IPR006964; NUDE_dom. DR PANTHER; PTHR10921; NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1; 1. DR PANTHER; PTHR10921:SF0; NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1; 1. DR Pfam; PF04880; NUDE_C; 1. PE 3: Inferred from homology; KW Centromere {ECO:0000256|ARBA:ARBA00023328}; KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}; KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212}; KW Kinetochore {ECO:0000256|ARBA:ARBA00022838}; KW Microtubule {ECO:0000256|ARBA:ARBA00022701}; KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Reference proteome {ECO:0000313|Proteomes:UP000694387}; KW Transport {ECO:0000256|ARBA:ARBA00022448}. FT DOMAIN 135..307 FT /note="NUDE" FT /evidence="ECO:0000259|Pfam:PF04880" FT REGION 314..344 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 356..418 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 30..187 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 329..339 FT /note="Low complexity" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 376..387 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 481 AA; 53274 MW; D1A9F0EC197B4B45 CRC64; MDGEDIPDFS SLKEETAYWK ELSLKYKQSF QEARDELVEF QEGSRELEAE LEAQLVQAEQ RNRDLQADNQ RLKYEVEALK EKLEHQYAQS YKQVSVLEDD LSQTRAIKEQ LHKYVRELEQ ANDDLERAKR ATIVSLEDFE QRLNQAIERN AFLESELDEK ESLLVSVQRL KDEARDLRQE LAVRERQQEV TRKSAPSSPT LDCEKMDSAV QASLSLPATP VGKGTENSFP SPKAIPNGFG TSPLTPSARI SALNIVGDLL RKVGALESKL AACRNFAKDQ ASRKSYISGN VNCGVMNSNG TKFSRSGHTS FFDKGAVNGF DPAPPPPGLG SSRPSSAPAT SFREPTLHQS WQQCGGEGLR TQEGRPAFDP GSVNCQERED TQKDNIKKNI PSHKESKHIH SIPARPRGRA QQTPGDALPP SLTGVPAELR WCPECPPALF SELPVPHSSP FSAFLPCSGK PSQIQSLPGV QRFGLVALAQ L //