ID   A0A9L0J901_EQUAS        Unreviewed;       289 AA.
AC   A0A9L0J901;
DT   13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2023, sequence version 1.
DT   02-SEP-2026, entry version 14.
DE   RecName: Full=Syntaxin-3 {ECO:0000256|ARBA:ARBA00072670};
GN   Name=STX3 {ECO:0000313|Ensembl:ENSEASP00005048853.1};
OS   Equus asinus (Donkey) (Equus africanus asinus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9793 {ECO:0000313|Ensembl:ENSEASP00005048853.1, ECO:0000313|Proteomes:UP000694387};
RN   [1] {ECO:0000313|Ensembl:ENSEASP00005048853.1, ECO:0000313|Proteomes:UP000694387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=33293529;
RA   Wang, C., Li, H., Guo, Y., Huang, J., Sun, Y., Min, J., Wang, J., Fang, X.,
RA   Zhao, Z., Wang, S., Zhang, Y., Liu, Q., Jiang, Q., Wang, X., Guo, Y., Yang,
RA   C., Wang, Y., Tian, F., Zhuang, G., Fan, Y., Gao, Q., Li, Y., Ju, Z., Li,
RA   J., Li, R., Hou, M., Yang, G., Liu, G., Liu, W., Guo, J., Pan, S., Fan, G.,
RA   Zhang, W., Zhang, R., Yu, J., Zhang, X., Yin, Q., Ji, C., Jin, Y., Yue, G.,
RA   Liu, M., Xu, J., Liu, S., Jordana, J., Noce, A., Amills, M., Wu, D.D., Li,
RA   S., Zhou, X. and Zhong, J.;
RT   "Donkey genomes provide new insights into domestication and selection for
RT   coat color.";
RL   Nat. Commun. 11:6014-6014(2020).
RN   [2] {ECO:0000313|Ensembl:ENSEASP00005048853.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2026) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC       pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC   -!- SIMILARITY: Belongs to the syntaxin family.
CC       {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR   AlphaFoldDB; A0A9L0J901; -.
DR   Ensembl; ENSEAST00005047497.1; ENSEASP00005048853.1; ENSEASG00005007989.2.
DR   GeneTree; ENSGT01030000234627; -.
DR   Proteomes; UP000694387; Chromosome 17.
DR   GO; GO:0012505; C:endomembrane system; IEA:TreeGrafter.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-ARBA.
DR   GO; GO:0120025; C:plasma membrane bounded cell projection; IEA:UniProtKB-ARBA.
DR   GO; GO:0098794; C:postsynapse; IEA:TreeGrafter.
DR   GO; GO:0031201; C:SNARE complex; IEA:TreeGrafter.
DR   GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR   GO; GO:0000149; F:SNARE binding; IEA:TreeGrafter.
DR   GO; GO:0098967; P:exocytic insertion of neurotransmitter receptor to postsynaptic membrane; IEA:TreeGrafter.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0048278; P:vesicle docking; IEA:TreeGrafter.
DR   GO; GO:0006906; P:vesicle fusion; IEA:TreeGrafter.
DR   CDD; cd00179; SynN; 1.
DR   FunFam; 1.20.5.110:FF:000023; Syntaxin 3; 1.
DR   FunFam; 1.20.58.70:FF:000001; Syntaxin 3; 1.
DR   Gene3D; 1.20.5.110; -; 1.
DR   Gene3D; 1.20.58.70; -; 1.
DR   InterPro; IPR010989; SNARE.
DR   InterPro; IPR045242; Syntaxin.
DR   InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR   InterPro; IPR006011; Syntaxin_N.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR19957; SYNTAXIN; 1.
DR   PANTHER; PTHR19957:SF34; SYNTAXIN-3; 1.
DR   Pfam; PF05739; SNARE; 1.
DR   Pfam; PF00804; Syntaxin; 1.
DR   SMART; SM00503; SynN; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   SUPFAM; SSF47661; t-snare proteins; 1.
DR   PROSITE; PS00914; SYNTAXIN; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW   ProRule:PRU00202};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694387};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        264..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          191..253
FT                   /note="T-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50192"
FT   COILED          39..108
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   289 AA;  33083 MW;  3E1A9431436F681C CRC64;
     MKDRLEQLKA KQLTQDDDAD EVEIAIDNTA FMDEFFSEIE ETRLNIDKIS EHVEEAKKLY
     SIILSAPIPE PKTKDDLEQL TTEIKKRANN VRNKLKSMER HIEEDEVRSS ADLRIRKSQH
     SVLSRKFVEV MTKYNEAQVD FRERSKGRIQ RQLEITGKKT TDEELEEMLE SGNPAIFTSG
     IIDSQISKQA LSEIEGRHKD IVRLESSIKE LHDMFMDIAM LVENQGAMID RIENNMDQSV
     GFVERAVADT KKAVKYQSEA RRKLIIIIVI VVVLLGILAL VIGLSVGLK
//