ID   A0A8C5FPT8_GADMO        Unreviewed;       709 AA.
AC   A0A8C5FPT8;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   08-OCT-2025, sequence version 2.
DT   10-JUN-2026, entry version 19.
DE   RecName: Full=Rab-GAP TBC domain-containing protein {ECO:0000259|PROSITE:PS50086};
GN   Name=tbc1d14 {ECO:0000313|Ensembl:ENSGMOP00000052581.1};
OS   Gadus morhua (Atlantic cod).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus.
OX   NCBI_TaxID=8049 {ECO:0000313|Ensembl:ENSGMOP00000052581.1, ECO:0000313|Proteomes:UP000694546};
RN   [1] {ECO:0000313|Ensembl:ENSGMOP00000052581.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSGMOP00000052581.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
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DR   AlphaFoldDB; A0A8C5FPT8; -.
DR   Ensembl; ENSGMOT00000039892.1; ENSGMOP00000052581.1; ENSGMOG00000018292.2.
DR   GeneTree; ENSGT00940000157250; -.
DR   Proteomes; UP000694546; Chromosome 17.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:TreeGrafter.
DR   GO; GO:0031267; F:small GTPase binding; IEA:TreeGrafter.
DR   FunFam; 1.10.8.270:FF:000008; Putative TBC1 domain family member 14; 1.
DR   FunFam; 1.10.10.750:FF:000005; TBC1 domain family member 14; 1.
DR   FunFam; 1.10.472.80:FF:000006; TBC1 domain family member 14; 1.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   InterPro; IPR050302; Rab_GAP_TBC_domain.
DR   PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR   PANTHER; PTHR47219:SF15; TBC1 DOMAIN FAMILY MEMBER 12 ISOFORM X1; 1.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694546}.
FT   DOMAIN          388..596
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   REGION          24..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          254..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          315..357
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        24..35
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..283
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   709 AA;  78977 MW;  28CBFB48F4D343DF CRC64;
     MHFFLTRNYL LTGRASFWLT HSSSSRSLPS YQPSPSSVPP SPTPIYYSSP RRLSLADPDP
     GGDRHSLASQ DSGLPTLEVS HPEAHTWPFG LPPLPAAATD DSPATLPLHP PSNGAVRKSS
     TFPRGCYDAA ARAGRAGPPS DGGSVCSASS MSTERSVSND DALDFVVASD SSVIVALETD
     ESCGIRHDDG RGGGGAGGSS QFSEVSLSSL GDLPRDVWSP NRRAGLTLGE PRQTRLAPLA
     NFFARSLFTK RVKEEPAEQK EAPGWNLFGK QPPRGGPVSP PSPRQNVRKS LAFEPLSTTA
     LILEDRPPNL PAKPAEEALK HRQQYEEMVA QAKKRELKEA QKRRKQQEQR CKLEESIGTA
     VQTWNQDILP NWTTTCTTRR VRDLWWQGVP PSVRGKVWSL AVGNELNITH ELYNICLARA
     KEKWKSLPTP SSHTEPEDLG SSDRESSLEL IKLDISRTFP HLCIFQQGGP YHDVLHSVLG
     AYTCYRPDVG YVQGMSFIAA VLILNLETAD AFIAFSNLLN KPCQMAFFRV DHSLMLTYFA
     AFEVFFEENL PKLFAHFKKN SLTPDIYLID WIFTLYSKSL PLDLACRVWD VFCRDGEEFL
     FRTALGLLHR YQDALQGMDF IQMAQLLTRL PDLVPGEQLF QHIAAVHMTC RAGKWPQVRT
     DRDGRTDGRG MAVTRFYFVS CDLRFGLRVW ERLSVFIICM RVFYGGLAT
//