id: F7A4N8
gene_symbol: CTDSP2
taxon:
  id: NCBITaxon:9796
  label: Equus caballus
status: COMPLETE
description: Kinase activity is unsupported for the selected short CTDSP2 protein model. Its sequence
  lacks the canonical human CTDSP2 catalytic region, so neither a normal phosphatase function nor a definitive
  alternative catalytic verdict can be transferred from the gene symbol.
source_documents:
- genes/HORSE/CTDSP2/CTDSP2-uniprot.txt
- genes/HORSE/CTDSP2/CTDSP2-bioinformatics/RESULTS.md
- genes/HORSE/CTDSP2/CTDSP2-bioinformatics/alignment.txt
- genes/human/CTDSP2/CTDSP2-uniprot.txt
predictions:
- source_method: ProtNLM2
  source_version: UniProt API snapshot 2026-09-08
  predicted_term:
    id: GO:0016301
    label: kinase activity
  predicted_term_type: GO_MF
  review:
    assessment: UNC
    confidence_score: 1
    summary: No kinase mechanism is supported for F7A4N8. The selected 174-residue sequence matches the
      N-terminal portion of human CTDSP2 but diverges before the FCP1 catalytic domain and lacks its conserved
      catalytic aspartates. A phosphatase-versus-kinase contradiction based only on the CTDSP2 gene name
      would therefore overstate the evidence for this exact input. The current sequence and domain record
      argue against an ordinary protein kinase but do not provide a structural or biochemical assessment
      sufficient to exclude every kinase activity. Resolve the protein model and inspect its structure
      before a definitive catalytic adjudication; no target GOA overlap exists.
    supported_by:
    - reference_id: file:HORSE/CTDSP2/CTDSP2-uniprot.txt
      supporting_text: ID   F7A4N8_HORSE            Unreviewed;       174 AA.
    - reference_id: file:human/CTDSP2/CTDSP2-uniprot.txt
      supporting_text: FT   ACT_SITE        107
    - reference_id: file:HORSE/CTDSP2/CTDSP2-bioinformatics/RESULTS.md
      supporting_text: Global alignment of cached UniProt sequences gives **97/170 identical paired residues
        (57.1%)**.
references:
- id: file:HORSE/CTDSP2/CTDSP2-uniprot.txt
  title: 'UniProtKB F7A4N8: selected horse CTDSP2 protein model'
- id: file:human/CTDSP2/CTDSP2-uniprot.txt
  title: 'UniProtKB O14595: human CTDSP2 catalytic features'
- id: file:HORSE/CTDSP2/CTDSP2-bioinformatics/RESULTS.md
  title: CTDSP2 human–horse sequence comparison