ndhA

Core Functions

Contributes a membrane-sector subunit to plastid NDH-1, supporting quinone-linked NADH dehydrogenase activity and proton-coupled electron transport.

Molecular Function:

quinone binding

Directly Involved In:

electron transport coupled proton transport

Cellular Locations:

chloroplast thylakoid membrane

In Complex:

NADH dehydrogenase complex

Supporting Evidence:

file:MISSI/ndhA/ndhA-uniprot.txt
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
file:MISSI/ndhA/ndhA-uniprot.txt
This subunit may bind ubiquinone.

References

file:MISSI/ndhA/ndhA-uniprot.txt

UniProtKB entry for Miscanthus sinensis ndhA

Suggested Experiments

Experiment: Measure NDH complex abundance and quinone reduction-linked electron transport in ndhA perturbation material.

Type: targeted functional assay

📚 Additional Documentation

Notes

(ndhA-notes.md)

Curation notes

QuickGO export is header-only; therefore no UniProt DR/InterPro/HAMAP-derived terms are listed as existing_annotations or proposed as NEW.
Core function uses broad quinone binding rather than the bacterial/mitochondrial ubiquinone wording because chloroplast NDH acts through plastoquinone.

📄 View Raw YAML

id: A0A0S2RMT7
gene_symbol: ndhA
product_type: PROTEIN
status: INITIALIZED
taxon:
  id: NCBITaxon:62337
  label: Miscanthus sinensis
description: Chloroplast NDH complex subunit A/H, a membrane-sector NADH-quinone oxidoreductase component that may bind quinone and supports proton-coupled electron transport.
existing_annotations: []
references:
- id: file:MISSI/ndhA/ndhA-uniprot.txt
  title: UniProtKB entry for Miscanthus sinensis ndhA
  findings: []
core_functions:
- description: Contributes a membrane-sector subunit to plastid NDH-1, supporting quinone-linked NADH dehydrogenase activity and proton-coupled electron transport.
  molecular_function:
    id: GO:0048038
    label: quinone binding
  contributes_to_molecular_function:
    id: GO:0016655
    label: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
  directly_involved_in:
  - id: GO:0015990
    label: electron transport coupled proton transport
  locations:
  - id: GO:0009535
    label: chloroplast thylakoid membrane
  in_complex:
    id: GO:0030964
    label: NADH dehydrogenase complex
  supported_by:
  - reference_id: file:MISSI/ndhA/ndhA-uniprot.txt
    supporting_text: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
  - reference_id: file:MISSI/ndhA/ndhA-uniprot.txt
    supporting_text: This subunit may bind ubiquinone.
proposed_new_terms: []
suggested_questions:
- question: Does Miscanthus ndhA affect plastid NDH stability or quinone-site function?
suggested_experiments:
- description: Measure NDH complex abundance and quinone reduction-linked electron transport in ndhA perturbation material.
  experiment_type: targeted functional assay

Gene Description