ID   Q1K6K5_NEUCR            Unreviewed;       516 AA.
AC   Q1K6K5;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   10-JUN-2026, entry version 62.
DE   RecName: Full=DNA-directed RNA polymerase III RPC4 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NCU01245 {ECO:0000313|EMBL:EAA31412.1};
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA31412.1, ECO:0000313|Proteomes:UP000001805};
RN   [1] {ECO:0000313|EMBL:EAA31412.1, ECO:0000313|Proteomes:UP000001805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC   {ECO:0000313|Proteomes:UP000001805};
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA   FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA   Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA   Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA   Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA   Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA   Lander E.S., Nusbaum C., Birren B.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM002240; EAA31412.1; -; Genomic_DNA.
DR   RefSeq; XP_960648.1; XM_955555.2.
DR   AlphaFoldDB; Q1K6K5; -.
DR   FunCoup; Q1K6K5; 134.
DR   STRING; 367110.Q1K6K5; -.
DR   PaxDb; 367110-Q1K6K5; -.
DR   GeneID; 3876796; -.
DR   KEGG; ncr:NCU01245; -.
DR   VEuPathDB; FungiDB:NCU01245; -.
DR   HOGENOM; CLU_033571_0_0_1; -.
DR   InParanoid; Q1K6K5; -.
DR   OMA; LQFPPMT; -.
DR   OrthoDB; 5836119at2759; -.
DR   Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR   GO; GO:0005666; C:RNA polymerase III complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0042797; P:tRNA transcription by RNA polymerase III; IBA:GO_Central.
DR   InterPro; IPR007811; RPC4.
DR   PANTHER; PTHR13408; DNA-DIRECTED RNA POLYMERASE III; 1.
DR   PANTHER; PTHR13408:SF0; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4; 1.
DR   Pfam; PF05132; RNA_pol_Rpc4; 1.
PE   4: Predicted;
KW   DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT   REGION          1..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          302..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..419
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..60
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..99
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..116
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..328
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        399..408
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        409..418
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   516 AA;  54961 MW;  9174994AA7829386 CRC64;
     MSQPPSRGRL APRGGRRPAA AAETPASGSL ATPAATPAPA SAAPSTSTSS AATPAASSAA
     KPGLKFKPKA VRRGEAERQR IAEEQQRLQD IRNEQESRRL ARANRGRGRG GGRGRGRGNF
     LMRGGRTASA AGPLSGGMGY GGGSSGGDGG GVDGFGTSNG FDANRINADM LYSLSLEDEE
     EKLENGLVRT KKKRAPMPMG IRRFEHEEEE VVMATAAEIE AQDAGVDVAA GDNDNDDDNS
     SDLFVDNGEG PVQIKDEGAV DTAVPRTIVK KEGGETEDVN MESIPEGVIK TPESPELKKK
     VMATTKEAEK PQEKKPKKPK ETEADFAQQD RERLVELFNH GTELEGHMFL FQLPVVLPPL
     KSAAPAPKVK PEPENDDVMM LDQPAMPKSS SRIDLTSEEA SKVKKENGEE ADADAEQEDM
     TREGGYVGQL VVRKSGKVEV SWGGVPLQMG LGIQANFLST AVIIKEDDVK PAQDQYTGAA
     YGMGRIQGSF VLAHTFGDEE EWVVDPSELV IADGEQ
//