id: Q7RWZ3
gene_symbol: NCU01540
locus_tag: NCU01540
taxon:
  id: NCBITaxon:367110
  label: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
status: COMPLETE
description: The GO predictions describe supported biological properties at lower specificity than the
  current supported annotations.
source_documents:
- genes/NEUCR/NCU01540/NCU01540-protnlm-source.json
- genes/NEUCR/NCU01540/NCU01540-protnlm-provenance.json
- genes/NEUCR/NCU01540/NCU01540-uniprot.txt
predictions:
- source_method: ProtNLM2
  source_version: UniProt API snapshot 2026-09-09
  source_reference_id: file:NEUCR/NCU01540/NCU01540-protnlm-source.json
  predicted_term:
    id: GO:0022857
    label: transmembrane transporter activity
  predicted_term_type: GO_MF
  review:
    assessment: LSP
    confidence_score: 2
    summary: The SPX-permease architecture and PANTHER Pho91 subfamily placement support phosphate transport
      by transfer from characterized fungal Pho87/Pho90/Pho91 transporters (PMID:17804816). The existing
      phosphate-transporter IBA is biologically supported and more specific than the prediction. The unresolved
      plasma versus vacuolar location does not undermine generic transmembrane transport.
    supported_by:
    - reference_id: file:NEUCR/NCU01540/NCU01540-uniprot.txt
      supporting_text: DR   PANTHER; PTHR10283:SF92; LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91; 1.
    - reference_id: PMID:17804816
      supporting_text: 'the low-affinity transporter Pho91 limits poly P accumulation in a strain

        lacking PHO85. This phenotype was not caused by a regulatory effect on the PHO

        pathway, but can be attributed to the unexpected localization of Pho91 in the

        vacuolar membrane.'
references:
- id: PMID:17804816
  title: Pho91 Is a vacuolar phosphate transporter that regulates phosphate and polyphosphate metabolism
    in Saccharomyces cerevisiae.
  findings: []
  full_text_unavailable: true
- id: file:NEUCR/NCU01540/NCU01540-uniprot.txt
  title: NCU01540-uniprot.txt
  findings: []
