ID   Q1K772_NEUCR            Unreviewed;       157 AA.
AC   Q1K772;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   02-SEP-2026, entry version 83.
DE   RecName: Full=SUMO-conjugating enzyme UBC9 {ECO:0000256|ARBA:ARBA00039165};
DE            EC=2.3.2.23 {ECO:0000256|ARBA:ARBA00012486};
DE   AltName: Full=Ubiquitin carrier protein 9 {ECO:0000256|ARBA:ARBA00044296};
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-18 kDa {ECO:0000256|ARBA:ARBA00081544};
GN   ORFNames=NCU04302 {ECO:0000313|EMBL:EAA31856.1};
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA31856.1, ECO:0000313|Proteomes:UP000001805};
RN   [1] {ECO:0000313|EMBL:EAA31856.1, ECO:0000313|Proteomes:UP000001805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC   {ECO:0000313|Proteomes:UP000001805};
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA   FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA   Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA   Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA   Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA   Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA   Lander E.S., Nusbaum C., Birren B.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- PATHWAY: Protein modification; protein sumoylation.
CC       {ECO:0000256|ARBA:ARBA00004718}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC       {ECO:0000256|ARBA:ARBA00094595, ECO:0000256|PROSITE-ProRule:PRU00388,
CC       ECO:0000256|RuleBase:RU362109}.
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DR   EMBL; CM002240; EAA31856.1; -; Genomic_DNA.
DR   RefSeq; XP_961092.1; XM_955999.2.
DR   AlphaFoldDB; Q1K772; -.
DR   SMR; Q1K772; -.
DR   FunCoup; Q1K772; 1158.
DR   STRING; 367110.Q1K772; -.
DR   PaxDb; 367110-Q1K772; -.
DR   GeneID; 3877214; -.
DR   KEGG; ncr:NCU04302; -.
DR   VEuPathDB; FungiDB:NCU04302; -.
DR   HOGENOM; CLU_030988_12_0_1; -.
DR   InParanoid; Q1K772; -.
DR   OMA; TWECGIP; -.
DR   OrthoDB; 6600758at2759; -.
DR   Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR   GO; GO:0000792; C:heterochromatin; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0106068; C:SUMO ligase complex; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0061656; F:SUMO conjugating enzyme activity; IBA:GO_Central.
DR   GO; GO:0061631; F:ubiquitin conjugating enzyme activity; IEA:UniProtKB-EC.
DR   GO; GO:0006281; P:DNA repair; IEA:EnsemblFungi.
DR   GO; GO:0016925; P:protein sumoylation; IEA:EnsemblFungi.
DR   CDD; cd23798; UBCc_UBE2I; 1.
DR   FunFam; 3.10.110.10:FF:000035; SUMO-conjugating enzyme ubc9; 1.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR050113; Ub_conjugating_enzyme-E2-like.
DR   InterPro; IPR000608; UBC.
DR   InterPro; IPR023313; UBQ-conjugating_AS.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   PANTHER; PTHR24067; UBIQUITIN-CONJUGATING ENZYME E2; 1.
DR   Pfam; PF00179; UQ_con; 1.
DR   SMART; SM00212; UBCc; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS00183; UBC_1; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU00388};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW   ECO:0000256|PROSITE-ProRule:PRU00388}.
FT   DOMAIN          3..156
FT                   /note="UBC core"
FT                   /evidence="ECO:0000259|PROSITE:PS50127"
FT   ACT_SITE        92
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10133"
SQ   SEQUENCE   157 AA;  18280 MW;  3AF90795036E3DAE CRC64;
     MALCQNRLQE ERKQWRKDHP FGFYARPQKN QQGVLDLKIW ECGIPGKEKT IWEGGLFKLT
     VTFPDEYPTK PPKCKFVPPL FHPNVYPSGT VCLSILNEEE AWKPAITMKQ ILLGIQDLLN
     DPNPESPAQA EAYNLFKKDR QEYERRIKRV VRENAAP
//