ID   Q7SCN3_NEUCR            Unreviewed;       341 AA.
AC   Q7SCN3;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   02-SEP-2026, entry version 96.
DE   RecName: Full=Ribosome production factor 2 homolog {ECO:0000256|RuleBase:RU367086};
DE   AltName: Full=Ribosome biogenesis protein RPF2 homolog {ECO:0000256|RuleBase:RU367086};
GN   ORFNames=NCU08595 {ECO:0000313|EMBL:EAA34504.1};
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA34504.1, ECO:0000313|Proteomes:UP000001805};
RN   [1] {ECO:0000313|EMBL:EAA34504.1, ECO:0000313|Proteomes:UP000001805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC   {ECO:0000313|Proteomes:UP000001805};
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA   FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA   Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA   Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA   Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA   Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA   Lander E.S., Nusbaum C., Birren B.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU367086}.
CC   -!- SIMILARITY: Belongs to the RPF2 family. {ECO:0000256|ARBA:ARBA00010782,
CC       ECO:0000256|RuleBase:RU367086}.
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DR   EMBL; CM002236; EAA34504.1; -; Genomic_DNA.
DR   RefSeq; XP_963740.1; XM_958647.3.
DR   AlphaFoldDB; Q7SCN3; -.
DR   SMR; Q7SCN3; -.
DR   FunCoup; Q7SCN3; 936.
DR   STRING; 367110.Q7SCN3; -.
DR   PaxDb; 367110-Q7SCN3; -.
DR   GeneID; 3879889; -.
DR   KEGG; ncr:NCU08595; -.
DR   VEuPathDB; FungiDB:NCU08595; -.
DR   HOGENOM; CLU_049783_0_0_1; -.
DR   InParanoid; Q7SCN3; -.
DR   OMA; VGLKPMF; -.
DR   OrthoDB; 407658at2759; -.
DR   Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:InterPro.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR039770; Rpf2.
DR   PANTHER; PTHR12728; BRIX DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12728:SF0; RIBOSOME PRODUCTION FACTOR 2 HOMOLOG; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367086};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT   DOMAIN          28..249
FT                   /note="Brix"
FT                   /evidence="ECO:0000259|PROSITE:PS50833"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..13
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   341 AA;  38897 MW;  4689EFA1037FCDE8 CRC64;
     MLRQVKPRTA RSKRALEKRA PKVNENPKTA LFLRGTTCSQ VTQDAMQDLY SLRQTHAKRF
     HKKNPVHPFE DASSLTFFSE KNDTSLILFG SSSKKRPHTI TFCRTFDYKM LDMLEFYLDP
     ETFRSIAQFK TKKVPVGTKP LMVFAGTAFE SPVPNAFTTA KSMLIDFFRG EPSDKIDVEG
     LQYCVVVSAD EPTSSSTDPS DPSTKPTLHL RAYLIRTKRS GQKLPRVEVE EHGPRMDFRL
     GRLQQPDADM LKAAMRKPKT NEERTKKNIS MDSIGDKIGR IHMGKLDLSE LQTRKMKGLK
     RSRDVVDEDF DDADMPMEGV KEVSDRIVGP RKKKARDVVE F
//