Gene Description

con-6 (conidiation-specific protein 6) is a small protein whose gene is expressed specifically during the late stages of macroconidiation in Neurospora crassa and is present in mature conidia. Its biochemical function is not established; it may protect dormant spores from desiccation.

Existing Annotations Review

GO Term	Evidence	Action	Reason
GO:0005737 cytoplasm	IBA GO_REF:0000033	ACCEPT	Summary: Accept: cytoplasm. Reason: Consistent with CON-6 being a conidiation-specific protein of the macroconidiation program.

Core Functions

Conidiation-specific protein expressed late in macroconidiation and retained in mature conidia; proposed to protect dormant spores from desiccation. Biochemical activity uncharacterized, and no process involvement is asserted here - con-6 is a temporal marker of the conidiation program rather than a demonstrated participant in it.

Supporting Evidence:

PMID:8224542
The gene con-6 of Neurospora crassa is expressed during the formation of asexual spores (conidia), but it is not expressed in mycelium.
file:NEUCR/con-6/con-6-uniprot.txt
May protect dormant spores from desiccation

References

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📚 Additional Documentation

Notes

(con-6-notes.md)

con-6 (Neurospora crassa) — curation notes

UniProt P34762. Conidiation-specific protein 6. Neurospora variant, structural-output tier.
- Expressed late in macroconidiation, present in mature conidia; may protect dormant spores from desiccation. [file:NEUCR/con-6/con-6-uniprot.txt "May protect dormant spores from desiccation"]. Biochemical function uncharacterized; single GOA annotation (cytoplasm, IBA).

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