id: B8BAB0
gene_symbol: B8BAB0
taxon:
  id: NCBITaxon:39946
  label: Oryza sativa subsp. indica
status: COMPLETE
description: >-
  The secretory, PG-associated BURP architecture does not establish a pollen-maturation role.
source_documents:
  - genes/ORYSI/B8BAB0/B8BAB0-uniprot.txt
  - genes/ORYSI/B8BAB0/B8BAB0-goa.tsv
  - genes/ORYSI/B8BAB0/B8BAB0-hypotheses/prediction-pollen-maturation/openscientist.md
predictions:
  - source_method: ProtNLM2
    source_version: UniProt 2024_06 pilot
    predicted_term:
      id: GO:0010152
      label: pollen maturation
    predicted_term_type: GO_BP
    review:
      assessment: PLI
      confidence_score: 0
      error_type: PARALOG_OVERANNOTATION
      summary: >-
        The target has a signal peptide and a PG-associated BURP-domain assignment, but the focused BURP
        comparison places B8BAB0 in the PG1beta-like cell-wall clade rather than the cereal anther RAFTIN/BURP-VII
        clade that supplies the reproductive-development precedent. The inspected evidence therefore supports
        an extracellular PG1beta-like protein, with candidate cell-wall leads needing separate verification,
        not a pollen-maturation role. ProtNLM2 appears to have over-transferred a pollen label across nonisofunctional
        BURP paralog clades.
      supported_by:
        - reference_id: file:ORYSI/B8BAB0/B8BAB0-uniprot.txt
          supporting_text: >-
            ID   B8BAB0_ORYSI            Unreviewed;       623 AA. ... DR   InterPro; IPR004873; BURP_dom.
            ... DR   InterPro; IPR051897; PG-associated_BURP. ... DR   PANTHER; PTHR31458:SF2; POLYGALACTURONASE
            1 BETA-LIKE PROTEIN 2; 1. ... FT   SIGNAL          1..21 ... FT   DOMAIN          384..595
            ... FT                   /note="BURP"
        - reference_id: file:ORYSI/B8BAB0/B8BAB0-hypotheses/prediction-pollen-maturation/openscientist.md
          supporting_text: >-
            is **not** a member of the cereal anther-specific **RAFTIN / BURP-VII** clade
references:
  - id: file:ORYSI/B8BAB0/B8BAB0-uniprot.txt
    title: B8BAB0-uniprot.txt
  - id: file:ORYSI/B8BAB0/B8BAB0-hypotheses/prediction-pollen-maturation/openscientist.md
    title: openscientist.md