FliF is the integral membrane structural subunit that oligomerizes to form the flagellar MS ring. The ring anchors the export apparatus and cytoplasmic switch complex during basal-body assembly; FliF is not itself a motor enzyme.
| GO Term | Evidence | Action | Reason |
|---|---|---|---|
| GO:0003774 cytoskeletal motor activity | IEA GO_REF:0000002 | MODIFY | Summary: FliF forms the MS-ring rotor scaffold and contributes to motor activity as part of the assembled flagellar motor. Reason: The activity is a property of the assembled motor; use the specific GO:0140605 term with contributes_to semantics for FliF. Proposed replacements: proton motive force-driven motor activity |
| GO:0005886 plasma membrane | IEA GO_REF:0000044 | ACCEPT | Summary: The FliF MS ring is embedded in the cytoplasmic membrane. Reason: Correct membrane localization. |
| GO:0009425 bacterial-type flagellum basal body | IEA GO_REF:0000044 | ACCEPT | Summary: FliF is a structural component of the basal body. Reason: Correct broader component annotation. |
| GO:0009431 bacterial-type flagellum basal body, MS ring | IEA GO_REF:0000002 | ACCEPT | Summary: FliF oligomers form the MS ring. Reason: This is the most specific and informative component annotation. |
| GO:0071973 bacterial-type flagellum-dependent cell motility | IEA GO_REF:0000002 | KEEP AS NON CORE | Summary: The FliF scaffold is required to construct a functional motility organelle. Reason: Correct downstream process, while basal-body assembly is the direct role. |
| GO:0005198 structural molecule activity | ISS file:PSEPK/fliF/fliF-uniprot.txt | NEW | Summary: FliF oligomerizes to form the structural MS ring of the flagellar basal body. Reason: Structural molecule activity captures the direct molecular role of this ring-forming subunit. Supporting Evidence: file:PSEPK/fliF/fliF-uniprot.txt The M ring is integral to the inner membrane of the cell file:PSEPK/fliF/fliF-deep-research-openscientist.md FliF is the flagellar M-ring/MS-ring protein of *Pseudomonas putida* KT2440 |
| GO:0044780 bacterial-type flagellum assembly | ISS file:PSEPK/fliF/fliF-uniprot.txt | NEW | Summary: FliF forms the MS ring during bacterial flagellum assembly. Reason: The structural role is a direct required step in basal-body assembly. Supporting Evidence: file:PSEPK/fliF/fliF-uniprot.txt The M ring is integral to the inner membrane of the cell file:PSEPK/fliF/fliF-deep-research-openscientist.md FliF is the flagellar M-ring/MS-ring protein of *Pseudomonas putida* KT2440 |
Loading supporting content…
Download this section (compressed HTML)Loading supporting content…
Download this section (compressed HTML)Loading supporting content…
Download this section (compressed HTML)Loading supporting content…
Download this section (compressed HTML)