fliP

UniProt ID: Q88EU8
Organism: Pseudomonas putida KT2440
Review Status: COMPLETE
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Gene Description

FliP is a conserved integral membrane subunit of the flagellar type III export gate. It contributes structurally to the export channel used to deliver rod, hook, and filament substrates during flagellum assembly.

Existing Annotations Review

GO Term Evidence Action Reason
GO:0005886 plasma membrane
IEA
GO_REF:0000120
ACCEPT
Summary: FliP is an integral component of the cytoplasmic membrane export gate.
Reason: Conserved topology supports this localization.
GO:0009306 protein secretion
IEA
GO_REF:0000120
MODIFY
Summary: The FliP-containing gate exports flagellar assembly substrates.
Reason: GO:0030254 specifically captures secretion through the type III export gate containing FliP.
Supporting Evidence:
file:PSEPK/fliP/fliP-deep-research-openscientist.md
FliP is a deeply conserved core component of the flagellar T3SS.
GO:0009425 bacterial-type flagellum basal body
IEA
GO_REF:0000120
ACCEPT
Summary: FliP is part of the basal-body-associated flagellar export apparatus.
Reason: This component localization is consistent with its conserved structural role.
Supporting Evidence:
file:PSEPK/fliP/fliP-deep-research-openscientist.md
FliP is therefore the major, most abundant subunit of the export-gate core.
GO:0016020 membrane
IEA
GO_REF:0000120
KEEP AS NON CORE
Summary: FliP is membrane embedded, but plasma membrane is more specific.
Reason: Correct but redundant broad localization.
GO:0044781 bacterial-type flagellum organization
IEA
GO_REF:0000104
MODIFY
Summary: FliP-dependent substrate export supports flagellar organization and assembly.
Reason: GO:0044780 bacterial-type flagellum assembly is the more direct and specific process for export-gate-dependent construction.
Supporting Evidence:
file:PSEPK/fliP/fliP-deep-research-openscientist.md
This apparatus is the machine that exports the structural subunits of the flagellum during its assembly.

Core Functions

Structural membrane-gate subunit required for export of flagellar assembly substrates.

References

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Deep Research

OpenScientist

(fliP-deep-research-openscientist.md)

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