FliP is a conserved integral membrane subunit of the flagellar type III export gate. It contributes structurally to the export channel used to deliver rod, hook, and filament substrates during flagellum assembly.
| GO Term | Evidence | Action | Reason |
|---|---|---|---|
| GO:0005886 plasma membrane | IEA GO_REF:0000120 | ACCEPT | Summary: FliP is an integral component of the cytoplasmic membrane export gate. Reason: Conserved topology supports this localization. |
| GO:0009306 protein secretion | IEA GO_REF:0000120 | MODIFY | Summary: The FliP-containing gate exports flagellar assembly substrates. Reason: GO:0030254 specifically captures secretion through the type III export gate containing FliP. Proposed replacements: protein secretion by the type III secretion system Supporting Evidence: file:PSEPK/fliP/fliP-deep-research-openscientist.md FliP is a deeply conserved core component of the flagellar T3SS. |
| GO:0009425 bacterial-type flagellum basal body | IEA GO_REF:0000120 | ACCEPT | Summary: FliP is part of the basal-body-associated flagellar export apparatus. Reason: This component localization is consistent with its conserved structural role. Supporting Evidence: file:PSEPK/fliP/fliP-deep-research-openscientist.md FliP is therefore the major, most abundant subunit of the export-gate core. |
| GO:0016020 membrane | IEA GO_REF:0000120 | KEEP AS NON CORE | Summary: FliP is membrane embedded, but plasma membrane is more specific. Reason: Correct but redundant broad localization. |
| GO:0044781 bacterial-type flagellum organization | IEA GO_REF:0000104 | MODIFY | Summary: FliP-dependent substrate export supports flagellar organization and assembly. Reason: GO:0044780 bacterial-type flagellum assembly is the more direct and specific process for export-gate-dependent construction. Proposed replacements: bacterial-type flagellum assembly Supporting Evidence: file:PSEPK/fliP/fliP-deep-research-openscientist.md This apparatus is the machine that exports the structural subunits of the flagellum during its assembly. |
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