id: O94400
gene_symbol: asr1
taxon:
  id: NCBITaxon:284812
  label: Schizosaccharomyces pombe (strain 972 / ATCC 24843)
status: COMPLETE
description: Metal binding is supported by the target zinc-finger architecture and is less precise than
  its existing zinc-specific annotation.
source_documents:
- genes/SCHPO/asr1/asr1-protnlm-source.xml
- genes/SCHPO/asr1/asr1-uniprot-source.json
- genes/SCHPO/asr1/asr1-uniprot.txt
predictions:
- source_method: ProtNLM2
  source_version: pre-release post-processed-2026_02_28k.xml
  source_reference_id: file:SCHPO/asr1/asr1-protnlm-source.xml
  predicted_term:
    id: GO:0046872
    label: metal ion binding
  predicted_term_type: GO_MF
  review:
    assessment: LSP
    confidence_score: 2
    summary: Metal ion binding is a credible consequence of the target zinc-finger architecture. The reviewed
      sequence record identifies a PHD finger at residues 122-170 through PROSITE-ProRule PRU00146 and
      an atypical RING region; the actual PHD sequence retains its cysteine/histidine-rich ligand pattern.
      This is a sequence/domain-based inference, with no direct target zinc-binding assay. Zinc and zinc-finger
      annotations already provide the more specific metal identity, and the XML itself records hydration
      from GO:0008270. The broad metal-ion prediction therefore recovers a known, less precise property
      rather than a novel function.
    supported_by:
    - reference_id: file:SCHPO/asr1/asr1-uniprot.txt
      supporting_text: 'FT   ZN_FING         122..170

        FT                   /note="PHD-type"

        FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00146"'
    - reference_id: file:SCHPO/asr1/asr1-uniprot.txt
      supporting_text: '     ETCRCVICGR SDHAEVLLLC DGCDDAYHTY CLNMDAVPIE EFYCPNCVLL'
references:
- id: file:SCHPO/asr1/asr1-uniprot.txt
  title: Frozen source record used for prediction assessment
  findings: []