ID   YQF7_SCHPO              Reviewed;         571 AA.
AC   O94400;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   02-SEP-2026, entry version 145.
DE   RecName: Full=PHD and RING finger domain-containing protein C126.07c;
GN   ORFNames=SPCC126.07c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329672; CAA22476.1; -; Genomic_DNA.
DR   PIR; T40911; T40911.
DR   AlphaFoldDB; O94400; -.
DR   SMR; O94400; -.
DR   BioGRID; 275631; 7.
DR   STRING; 284812.O94400; -.
DR   iPTMnet; O94400; -.
DR   PaxDb; 284812-O94400; -.
DR   KEGG; spo:2539058; -.
DR   PomBase; SPCC126.07c; -.
DR   VEuPathDB; FungiDB:SPCC126.07c; -.
DR   eggNOG; KOG0825; Eukaryota.
DR   HOGENOM; CLU_026721_0_0_1; -.
DR   InParanoid; O94400; -.
DR   OMA; GDWYCME; -.
DR   PhylomeDB; O94400; -.
DR   PRO; PR:O94400; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0000785; C:chromatin; IEA:UniProtKB-ARBA.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProtKB-ARBA.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; ISO:PomBase.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:UniProtKB-ARBA.
DR   CDD; cd15536; PHD_PHRF1; 1.
DR   CDD; cd16448; RING-H2; 1.
DR   FunFam; 3.30.40.10:FF:001789; PHD and RING finger domain-containing protein C126.07c; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR   InterPro; IPR047157; PHRF1/Atg35.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR12618; PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR12618:SF20; PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00628; PHD; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00184; RING; 2.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..571
FT                   /note="PHD and RING finger domain-containing protein
FT                   C126.07c"
FT                   /id="PRO_0000303919"
FT   ZN_FING         18..79
FT                   /note="RING-type 1; atypical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   ZN_FING         122..170
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00146"
FT   ZN_FING         125..168
FT                   /note="RING-type 2; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          305..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..324
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..356
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..377
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   571 AA;  64468 MW;  34C23259CA54E6CB CRC64;
     MNAEEDPKPA DSDSSEECII CLSNLPNCPL DQWDSSSVPA SISSTLDGLR IAKIPCGHYF
     HNHCLESWCR VANTCPLCRT EFLKVDVLEF VKGPWYRAYP VEEKTQSVAN AGEPFEDEGS
     ETCRCVICGR SDHAEVLLLC DGCDDAYHTY CLNMDAVPIE EFYCPNCVLL NYQENETLSS
     RISLSRRGQT RRRRVGAAAR ASRVSQQQQR AWTRAWNAIR NRAWDALNSD LSYYGMQQER
     LPARDVSSEL LRRRIESARL RSNQLNEPVE QPRVVQTPVT NASEQQAWND FDEILHANSS
     VHSVATEATI SNPRPSSGRF QQTPIEEHHQ QDTRFVNDPN STSHDRRQKR PTRRHIPCSN
     KSSGSSTVLG NNSSSKSENS FLASLISNIN QPSTSRIDTS FMLSLQHEIK NSHSEASDGT
     SDVHLTPLFS NLSPRPSHVP LSPREISNDN LDDHLIELSE PGEIVDNHLV NDTSMHQRRT
     SGRHDLVHSS KKVSYETKYR IERLVNAALK PYYREAKISK DQFALFNKNI CRSVYTALSD
     GTLSLEGPQQ HKISKTIREK VVNCIQSLSN D
//