{
  "annotationScore": 3.0,
  "comments": [
    {
      "commentType": "FUNCTION",
      "texts": [
        {
          "evidences": [
            {
              "evidenceCode": "ECO:0000269",
              "id": "9237993",
              "source": "PubMed"
            }
          ],
          "value": "Binds to centromeric K-type repeat DNA and ARS3002 DNA. The CBH-binding consensus sequence is Py-Pu-A-T-A-T-Py-Pu-T-A"
        }
      ]
    },
    {
      "commentType": "SUBCELLULAR LOCATION",
      "subcellularLocations": [
        {
          "location": {
            "id": "SL-0191",
            "value": "Nucleus"
          }
        },
        {
          "location": {
            "id": "SL-0047",
            "value": "Chromosome, centromere"
          }
        }
      ]
    }
  ],
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    "entryVersion": 164,
    "firstPublicDate": "2001-01-11",
    "lastAnnotationUpdateDate": "2026-09-02",
    "lastSequenceUpdateDate": "2000-10-01",
    "sequenceVersion": 2
  },
  "entryType": "UniProtKB reviewed (Swiss-Prot)",
  "extraAttributes": {
    "countByCommentType": {
      "FUNCTION": 1,
      "SUBCELLULAR LOCATION": 1
    },
    "countByFeatureType": {
      "Chain": 1,
      "Domain": 1,
      "Sequence conflict": 1
    },
    "uniParcId": "UPI000012718C"
  },
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    {
      "description": "CENP-B homolog protein 1",
      "featureId": "PRO_0000126134",
      "location": {
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          "modifier": "EXACT",
          "value": 514
        },
        "start": {
          "modifier": "EXACT",
          "value": 1
        }
      },
      "type": "Chain"
    },
    {
      "description": "HTH CENPB-type",
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        {
          "evidenceCode": "ECO:0000255",
          "id": "PRU00583",
          "source": "PROSITE-ProRule"
        }
      ],
      "location": {
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          "modifier": "EXACT",
          "value": 144
        },
        "start": {
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          "value": 69
        }
      },
      "type": "Domain"
    },
    {
      "alternativeSequence": {
        "alternativeSequences": [
          "M"
        ],
        "originalSequence": "I"
      },
      "description": "in Ref. 1; AAB80698",
      "evidences": [
        {
          "evidenceCode": "ECO:0000305"
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        "start": {
          "modifier": "EXACT",
          "value": 168
        }
      },
      "type": "Sequence conflict"
    }
  ],
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    {
      "geneName": {
        "value": "cbh1"
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        {
          "value": "SPAC9E9.10c"
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        {
          "value": "cbh"
        }
      ]
    }
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    {
      "category": "Cellular component",
      "id": "KW-0137",
      "name": "Centromere"
    },
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    },
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      "category": "Technical term",
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      "name": "Direct protein sequencing"
    },
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      "category": "Molecular function",
      "id": "KW-0238",
      "name": "DNA-binding"
    },
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      "category": "Cellular component",
      "id": "KW-0539",
      "name": "Nucleus"
    },
    {
      "category": "Technical term",
      "id": "KW-1185",
      "name": "Reference proteome"
    }
  ],
  "organism": {
    "commonName": "Fission yeast",
    "lineage": [
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      "Fungi",
      "Dikarya",
      "Ascomycota",
      "Taphrinomycotina",
      "Schizosaccharomycetes",
      "Schizosaccharomycetales",
      "Schizosaccharomycetaceae",
      "Schizosaccharomyces"
    ],
    "scientificName": "Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
    "taxonId": 284812
  },
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      "fullName": {
        "value": "CENP-B homolog protein 1"
      },
      "shortNames": [
        {
          "value": "CBHP-1"
        }
      ]
    }
  },
  "proteinExistence": "1: Evidence at protein level",
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    {
      "citation": {
        "authors": [
          "Lee J.-K.",
          "Huberman J.A.",
          "Hurwitz J."
        ],
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          {
            "database": "PubMed",
            "id": "9237993"
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          {
            "database": "DOI",
            "id": "10.1073/pnas.94.16.8427"
          }
        ],
        "citationType": "journal article",
        "firstPage": "8427",
        "id": "9237993",
        "journal": "Proc. Natl. Acad. Sci. U.S.A.",
        "lastPage": "8432",
        "publicationDate": "1997",
        "title": "Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe.",
        "volume": "94"
      },
      "referenceComments": [
        {
          "type": "STRAIN",
          "value": "972 / ATCC 24843"
        }
      ],
      "referenceNumber": 1,
      "referencePositions": [
        "NUCLEOTIDE SEQUENCE [MRNA]",
        "PARTIAL PROTEIN SEQUENCE",
        "FUNCTION"
      ]
    },
    {
      "citation": {
        "authors": [
          "Wood V.",
          "Gwilliam R.",
          "Rajandream M.A.",
          "Lyne M.H.",
          "Lyne R.",
          "Stewart A.",
          "Sgouros J.G.",
          "Peat N.",
          "Hayles J.",
          "Baker S.G.",
          "Basham D.",
          "Bowman S.",
          "Brooks K.",
          "Brown D.",
          "Brown S.",
          "Chillingworth T.",
          "Churcher C.M.",
          "Collins M.",
          "Connor R.",
          "Cronin A.",
          "Davis P.",
          "Feltwell T.",
          "Fraser A.",
          "Gentles S.",
          "Goble A.",
          "Hamlin N.",
          "Harris D.E.",
          "Hidalgo J.",
          "Hodgson G.",
          "Holroyd S.",
          "Hornsby T.",
          "Howarth S.",
          "Huckle E.J.",
          "Hunt S.",
          "Jagels K.",
          "James K.D.",
          "Jones L.",
          "Jones M.",
          "Leather S.",
          "McDonald S.",
          "McLean J.",
          "Mooney P.",
          "Moule S.",
          "Mungall K.L.",
          "Murphy L.D.",
          "Niblett D.",
          "Odell C.",
          "Oliver K.",
          "O'Neil S.",
          "Pearson D.",
          "Quail M.A.",
          "Rabbinowitsch E.",
          "Rutherford K.M.",
          "Rutter S.",
          "Saunders D.",
          "Seeger K.",
          "Sharp S.",
          "Skelton J.",
          "Simmonds M.N.",
          "Squares R.",
          "Squares S.",
          "Stevens K.",
          "Taylor K.",
          "Taylor R.G.",
          "Tivey A.",
          "Walsh S.V.",
          "Warren T.",
          "Whitehead S.",
          "Woodward J.R.",
          "Volckaert G.",
          "Aert R.",
          "Robben J.",
          "Grymonprez B.",
          "Weltjens I.",
          "Vanstreels E.",
          "Rieger M.",
          "Schaefer M.",
          "Mueller-Auer S.",
          "Gabel C.",
          "Fuchs M.",
          "Duesterhoeft A.",
          "Fritzc C.",
          "Holzer E.",
          "Moestl D.",
          "Hilbert H.",
          "Borzym K.",
          "Langer I.",
          "Beck A.",
          "Lehrach H.",
          "Reinhardt R.",
          "Pohl T.M.",
          "Eger P.",
          "Zimmermann W.",
          "Wedler H.",
          "Wambutt R.",
          "Purnelle B.",
          "Goffeau A.",
          "Cadieu E.",
          "Dreano S.",
          "Gloux S.",
          "Lelaure V.",
          "Mottier S.",
          "Galibert F.",
          "Aves S.J.",
          "Xiang Z.",
          "Hunt C.",
          "Moore K.",
          "Hurst S.M.",
          "Lucas M.",
          "Rochet M.",
          "Gaillardin C.",
          "Tallada V.A.",
          "Garzon A.",
          "Thode G.",
          "Daga R.R.",
          "Cruzado L.",
          "Jimenez J.",
          "Sanchez M.",
          "del Rey F.",
          "Benito J.",
          "Dominguez A.",
          "Revuelta J.L.",
          "Moreno S.",
          "Armstrong J.",
          "Forsburg S.L.",
          "Cerutti L.",
          "Lowe T.",
          "McCombie W.R.",
          "Paulsen I.",
          "Potashkin J.",
          "Shpakovski G.V.",
          "Ussery D.",
          "Barrell B.G.",
          "Nurse P."
        ],
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          {
            "database": "PubMed",
            "id": "11859360"
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          {
            "database": "DOI",
            "id": "10.1038/nature724"
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        "id": "11859360",
        "journal": "Nature",
        "lastPage": "880",
        "publicationDate": "2002",
        "title": "The genome sequence of Schizosaccharomyces pombe.",
        "volume": "415"
      },
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        {
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          "value": "972 / ATCC 24843"
        }
      ],
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      ]
    }
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    "length": 514,
    "md5": "DB4D11D03CED9D24E1FD9DB60058D36E",
    "molWeight": 59865,
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      ]
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    },
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    {
      "database": "RefSeq",
      "id": "NP_594583.1",
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        {
          "key": "NucleotideSequenceId",
          "value": "NM_001020012.3"
        }
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    },
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    {
      "database": "PomBase",
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    },
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    {
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    {
      "database": "OMA",
      "id": "WIKTEWP",
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          "key": "Fingerprint",
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    {
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}
