ID   A0A8J0SCI2_XENTR        Unreviewed;       265 AA.
AC   A0A8J0SCI2;
DT   25-MAY-2022, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 1.
DT   10-JUN-2026, entry version 20.
DE   SubName: Full=Gastrula zinc finger protein XlCGF17.1-like {ECO:0000313|RefSeq:XP_012810399.1};
GN   Name=LOC101732730 {ECO:0000313|RefSeq:XP_012810399.1,
GN   ECO:0000313|Xenbase:XB-GENE-29086363};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|Proteomes:UP000008143, ECO:0000313|RefSeq:XP_012810399.1};
RN   [1] {ECO:0000313|RefSeq:XP_012810399.1}
RP   IDENTIFICATION.
RC   STRAIN=Nigerian {ECO:0000313|RefSeq:XP_012810399.1};
RC   TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_012810399.1};
RG   RefSeq;
RL   Submitted (JAN-2026) to UniProtKB.
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC       {ECO:0000256|ARBA:ARBA00003767}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000256|ARBA:ARBA00006991}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_012810399.1; XM_012954945.3.
DR   AlphaFoldDB; A0A8J0SCI2; -.
DR   GeneID; 101732730; -.
DR   KEGG; xtr:101732730; -.
DR   AGR; Xenbase:XB-GENE-29086363; -.
DR   Xenbase; XB-GENE-29086363; LOC101732730.
DR   OMA; RETFHVY; -.
DR   OrthoDB; 8113227at2759; -.
DR   Proteomes; UP000008143; Chromosome 9.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   FunFam; 3.30.160.60:FF:001007; Zinc finger protein 1184; 3.
DR   FunFam; 3.30.160.60:FF:002592; Zinc finger protein 527; 3.
DR   FunFam; 3.30.160.60:FF:000936; Zinc finger protein 577; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24381:SF440; OOCYTE ZINC FINGER PROTEIN XLCOF7.1-LIKE; 1.
DR   PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR   Pfam; PF00096; zf-C2H2; 5.
DR   SMART; SM00355; ZnF_C2H2; 8.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   DOMAIN          37..64
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          65..92
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          93..120
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          121..148
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          149..176
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          177..204
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          205..232
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          233..260
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..12
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   265 AA;  31205 MW;  101140846C59E501 CRC64;
     MGSSQNTLQM MDNNHDENSH QSLHKSHITN NKLRRKYSCN ECQKHFNNKR DFHIHQRSHK
     REKPFSCSEC GKCFSYQSRL NHHQRTHTGE KPFSCSECGK CFSRKFYRDC HQRTHTGEKP
     FSCSECGKCF SYQSRLSRHQ RTHTGEKPFS CPECGKCFSR KVYRDCHQRT HTGEKPFSCS
     ECGKCFSSKF YRDCHQRTHT GEKPFSCSEC GKCFSQQSDL KIHYKTHTGE KPFSCSECGK
     CFLRKSQLDR HERTHKGEKP FSYSK
//