GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB P07550 ADRB2 is_active_in GO:0005886 plasma membrane cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0004514|FB:FBgn0035538|FB:FBgn0038063|FB:FBgn0038541|FB:FBgn0038542|FB:FBgn0038980|FB:FBgn0250910|MGI:MGI:87938|MGI:MGI:94924|MGI:MGI:94925|MGI:MGI:94927|MGI:MGI:99578|PANTHER:PTN002798190|RGD:2054|RGD:2055|RGD:2056|RGD:2058|RGD:2059|RGD:2060|RGD:2520|RGD:2521|RGD:2523|UniProtKB:P07550|UniProtKB:P08588|UniProtKB:P08913|UniProtKB:P13945|UniProtKB:P14416|UniProtKB:P18089|UniProtKB:P18825|UniProtKB:P18871|UniProtKB:P21728|UniProtKB:P21918|UniProtKB:P35348|UniProtKB:P35368|UniProtKB:P35462|UniProtKB:P56489|WB:WBGene00004777 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20250903 UniProtKB P07550 ADRB2 involved_in GO:0043410 positive regulation of MAPK cascade biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0035538|MGI:MGI:104773|MGI:MGI:87939|PANTHER:PTN001205212|RGD:2055|UniProtKB:P07550|UniProtKB:P13945|UniProtKB:P35348|UniProtKB:P35368 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20250903 UniProtKB P07550 ADRB2 involved_in GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:87938|MGI:MGI:87939|PANTHER:PTN001205212|RGD:2061|UniProtKB:P07550|UniProtKB:P08588|UniProtKB:P13945 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20250903 UniProtKB P07550 ADRB2 involved_in GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:87938|PANTHER:PTN002798499 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20200330 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000318 IBA GO_REF:0000033 MGI:MGI:87938|PANTHER:PTN002798499|RGD:2060|UniProtKB:P07550 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20200330 UniProtKB P07550 ADRB2 enables GO:0051380 norepinephrine binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002798499|UniProtKB:P07550 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20200330 UniProtKB P07550 ADRB2 enables GO:0004930 G protein-coupled receptor activity molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000276 9606 Homo sapiens InterPro Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 enables GO:0004935 adrenergic receptor activity molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR002233 9606 Homo sapiens InterPro Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 enables GO:0004939 beta-adrenergic receptor activity molecular_function ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00089398 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:P18762|ensembl:ENSMUSP00000062256|InterPro:IPR000332 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 located_in GO:0005794 Golgi apparatus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0132 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0039 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 involved_in GO:0006940 regulation of smooth muscle contraction biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000332 9606 Homo sapiens InterPro Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 involved_in GO:0007186 G protein-coupled receptor signaling pathway biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000276|InterPro:IPR002233 9606 Homo sapiens InterPro Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 involved_in GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000332 9606 Homo sapiens InterPro Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 located_in GO:0016020 membrane cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:P18762|ensembl:ENSMUSP00000062256|InterPro:IPR000276|InterPro:IPR000332|InterPro:IPR002233|InterPro:IPR017452 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 involved_in GO:0097746 blood vessel diameter maintenance biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000332 9606 Homo sapiens InterPro Beta-2 adrenergic receptor 20260428 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17148612 UniProtKB:P32121 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17170700 UniProtKB:P12931 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20353789 UniProtKB:Q5TCQ9 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23208550 UniProtKB:P32121 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23208550 UniProtKB:Q96B67 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23236378 UniProtKB:Q96B67 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23291003 UniProtKB:P30542 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28298427 UniProtKB:P61978 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28298427 UniProtKB:Q99685 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:A0AVK6 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O00472 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q13573 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q15486 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q15910-2 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q5M9N0-2 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q5T0J7-2 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q658K8 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8N0U2 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8WVD3 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9H0X6 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NR21-5 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NSI6-4 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9UII2 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9ULD4-2 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:A4D2P6 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:O75970 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:P78352 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q07157 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q12959 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q14005 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q14160 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q15700 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q5TCQ9 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q68DX3 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q86UL8 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q86UT5 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q8N448 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q8NI35 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q8TBB1 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q92796 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q96QZ7 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q99767 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q9C0E4 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q9P202 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36115835 UniProtKB:Q9Y3R0 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:39083597 UniProtKB:O60894 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:39083597 UniProtKB:O60896 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:9671706 UniProtKB:O14745 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:15518545 UniProtKB:P07550 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:19763081 UniProtKB:P07550 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:20590567 UniProtKB:P07550 9606 Homo sapiens IntAct Beta-2 adrenergic receptor 20260425 UniProtKB P07550 ADRB2 located_in GO:0005634 nucleus cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 enables GO:0008179 adenylate cyclase binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0010666 positive regulation of cardiac muscle cell apoptotic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0010667 negative regulation of cardiac muscle cell apoptotic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 located_in GO:0016324 apical plasma membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 enables GO:0019899 enzyme binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0061885 positive regulation of mini excitatory postsynaptic potential biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 is_active_in GO:0098992 neuronal dense core vesicle cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0106134 positive regulation of cardiac muscle cell contraction biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:0120162 positive regulation of cold-induced thermogenesis biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 involved_in GO:1904646 cellular response to amyloid-beta biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P18762|ensembl:ENSMUSP00000062256 9606 Homo sapiens Ensembl Beta-2 adrenergic receptor 20260422 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Beta-2 adrenergic receptor 20251115 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000269 EXP PMID:20559325 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20251027 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000269 EXP PMID:25220262 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20251027 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000269 EXP PMID:2831218 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20251027 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000269 EXP PMID:7915137 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20251027 UniProtKB P07550 ADRB2 involved_in GO:0071875 adrenergic receptor signaling pathway biological_process ECO:0000316 IGI PMID:20395454 ComplexPortal:CPX-1070 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20250915 UniProtKB P07550 ADRB2 involved_in GO:1900451 positive regulation of glutamate receptor signaling pathway biological_process ECO:0000316 IGI PMID:20395454 ComplexPortal:CPX-1070 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20250915 UniProtKB P07550 ADRB2 involved_in GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process ECO:0000316 IGI PMID:20395454 ComplexPortal:CPX-1070|UniProtKB:P18762 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20250905 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000250 ISS GO_REF:0000024 MGI:MGI:87938 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000315 IMP PMID:2831218 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 is_active_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:19584355 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 involved_in GO:0010666 positive regulation of cardiac muscle cell apoptotic process biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P18762 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 involved_in GO:0010667 negative regulation of cardiac muscle cell apoptotic process biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P18762 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 involved_in GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process ECO:0000305 IC PMID:2831218 GO:0004941 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 involved_in GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P18762 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 involved_in GO:0106134 positive regulation of cardiac muscle cell contraction biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P18762 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20250516 UniProtKB P07550 ADRB2 enables GO:0042803 protein homodimerization activity molecular_function ECO:0000353 IPI PMID:15123695 UniProtKB:P07550 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20250125 UniProtKB P07550 ADRB2 enables GO:0044877 protein-containing complex binding molecular_function ECO:0000353 IPI PMID:20395454 ComplexPortal:CPX-1070 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20240924 UniProtKB P07550 ADRB2 involved_in GO:0098990 AMPA selective glutamate receptor signaling pathway biological_process ECO:0000316 IGI PMID:20395454 ComplexPortal:CPX-1070 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20240719 UniProtKB P07550 ADRB2 involved_in GO:0045744 negative regulation of G protein-coupled receptor signaling pathway biological_process ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20240215 UniProtKB P07550 ADRB2 involved_in GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20240215 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23166351 UniProtKB:P46934 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20210818 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23166351 UniProtKB:Q8TEY7 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20210818 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23166351 UniProtKB:Q9P0N8 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20210818 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23166351 UniProtKB:Q9Y2K6 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20210818 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:23166351 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20210818 UniProtKB P07550 ADRB2 located_in GO:0005794 Golgi apparatus cellular_component ECO:0000314 IDA PMID:27481942 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20200707 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:27481942 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20200707 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868658 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868659 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868660 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868661 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8869438 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8871193 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 located_in GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8871194 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20190206 UniProtKB P07550 ADRB2 involved_in GO:0120162 positive regulation of cold-induced thermogenesis biological_process ECO:0000250 ISS PMID:12387862 UniProtKB:P18762 9606 Homo sapiens YuBioLab Beta-2 adrenergic receptor 20180612 UniProtKB P07550 ADRB2 enables GO:0001540 amyloid-beta binding molecular_function ECO:0000314 IDA PMID:20395454 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20170525 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000303 NAS PMID:20395454 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20170525 UniProtKB P07550 ADRB2 located_in GO:0016020 membrane cellular_component ECO:0000303 NAS PMID:20395454 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20170525 UniProtKB P07550 ADRB2 involved_in GO:1904646 cellular response to amyloid-beta biological_process ECO:0000316 IGI PMID:20395454 ComplexPortal:CPX-1070|UniProtKB:P18762 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20170525 UniProtKB P07550 ADRB2 involved_in GO:1990911 response to psychosocial stress biological_process ECO:0000304 TAS PMID:20395454 9606 Homo sapiens ARUK-UCL Beta-2 adrenergic receptor 20170525 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000314 IDA PMID:19710023 9606 Homo sapiens CAFA Beta-2 adrenergic receptor 20161024 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:19710023 9606 Homo sapiens CAFA Beta-2 adrenergic receptor 20161024 UniProtKB P07550 ADRB2 involved_in GO:0071875 adrenergic receptor signaling pathway biological_process ECO:0000314 IDA PMID:19710023 9606 Homo sapiens CAFA Beta-2 adrenergic receptor 20161024 UniProtKB P07550 ADRB2 located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-5696968 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160519 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8851797 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8852167 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866269 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866283 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8867754 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8867756 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868071 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868072 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868230 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868236 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868648 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868651 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8868661 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8982641 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20160113 UniProtKB P07550 ADRB2 involved_in GO:1901098 positive regulation of autophagosome maturation biological_process ECO:0000314 IDA PMID:23708524 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20150813 UniProtKB P07550 ADRB2 involved_in GO:1904504 positive regulation of lipophagy biological_process ECO:0000314 IDA PMID:23708524 9606 Homo sapiens GO_Central Beta-2 adrenergic receptor 20150813 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24405750 UniProtKB:Q9P003 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20150225 UniProtKB P07550 ADRB2 part_of GO:0043235 signaling receptor complex cellular_component ECO:0000314 IDA PMID:23382219 9606 Homo sapiens MGI Beta-2 adrenergic receptor 20131224 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20733053 UniProtKB:Q96L92 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20130716 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-379044 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-744886 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-744887 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8982645 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9609310 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9611751 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9611851 9606 Homo sapiens Reactome Beta-2 adrenergic receptor 20130528 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19584355 UniProtKB:P40337 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20111114 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19584355 UniProtKB:Q9H6Z9 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20111114 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19424180 UniProtKB:Q8TEY7 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20091115 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19424180 UniProtKB:Q9Y2K6 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20091115 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:12297500 9606 Homo sapiens BHF-UCL Beta-2 adrenergic receptor 20080903 UniProtKB P07550 ADRB2 enables GO:0015459 potassium channel regulator activity molecular_function ECO:0000314 IDA PMID:12297500 9606 Homo sapiens BHF-UCL Beta-2 adrenergic receptor 20080903 UniProtKB P07550 ADRB2 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:9235896 9606 Homo sapiens MGI Beta-2 adrenergic receptor 20060921 UniProtKB P07550 ADRB2 enables GO:0004941 beta2-adrenergic receptor activity molecular_function ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20060628 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15123695 UniProtKB:P13945 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20060628 UniProtKB P07550 ADRB2 involved_in GO:0006898 receptor-mediated endocytosis biological_process ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20060628 UniProtKB P07550 ADRB2 part_of GO:0043235 signaling receptor complex cellular_component ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20060628 UniProtKB P07550 ADRB2 involved_in GO:0043410 positive regulation of MAPK cascade biological_process ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20060628 UniProtKB P07550 ADRB2 enables GO:0051380 norepinephrine binding molecular_function ECO:0000314 IDA PMID:15123695 9606 Homo sapiens HGNC-UCL Beta-2 adrenergic receptor 20060628 UniProtKB P07550 ADRB2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:9560162 UniProtKB:O14745 9606 Homo sapiens UniProt Beta-2 adrenergic receptor 20051215 UniProtKB P07550 ADRB2 located_in GO:0005764 lysosome cellular_component ECO:0000304 TAS PMID:9507004 9606 Homo sapiens PINC Beta-2 adrenergic receptor 20030904 UniProtKB P07550 ADRB2 located_in GO:0005768 endosome cellular_component ECO:0000304 TAS PMID:10734107 9606 Homo sapiens PINC Beta-2 adrenergic receptor 20030904 UniProtKB P07550 ADRB2 involved_in GO:0007166 cell surface receptor signaling pathway biological_process ECO:0000304 TAS PMID:1371121 9606 Homo sapiens PINC Beta-2 adrenergic receptor 20030904 UniProtKB P07550 ADRB2 involved_in GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway biological_process ECO:0000304 TAS PMID:2823249 9606 Homo sapiens PINC Beta-2 adrenergic receptor 20030904 UniProtKB P07550 ADRB2 involved_in GO:0008333 endosome to lysosome transport biological_process ECO:0000304 TAS PMID:9507004 9606 Homo sapiens PINC Beta-2 adrenergic receptor 20030904