GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q8N3C0 ASCC3 enables GO:0003723 RNA binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN001940172|UniProtKB:Q38E01 9606 Homo sapiens GO_Central Activating signal cointegrator 1 complex subunit 3 20250903 UniProtKB Q8N3C0 ASCC3 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002375404|UniProtKB:Q8N3C0 9606 Homo sapiens GO_Central Activating signal cointegrator 1 complex subunit 3 20250412 UniProtKB Q8N3C0 ASCC3 enables GO:0043138 3'-5' DNA helicase activity molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002375404|UniProtKB:Q8N3C0 9606 Homo sapiens GO_Central Activating signal cointegrator 1 complex subunit 3 20171201 UniProtKB Q8N3C0 ASCC3 enables GO:0003676 nucleic acid binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR011545 9606 Homo sapiens InterPro Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 enables GO:0004386 helicase activity molecular_function ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00026537 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 enables GO:0005524 ATP binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR011545 9606 Homo sapiens InterPro Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 located_in GO:0005829 cytosol cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0091 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 located_in GO:0016607 nuclear speck cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0186 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 enables GO:0016887 ATP hydrolysis activity molecular_function ECO:0007322 IEA GO_REF:0000116 RHEA:13065 9606 Homo sapiens RHEA Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 enables GO:0043138 3'-5' DNA helicase activity molecular_function ECO:0000501 IEA GO_REF:0000003 EC:5.6.2.4 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 part_of GO:0180022 RQC-trigger complex cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00091275 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20260428 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:P53701 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q8N9N2-2 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q9H1I8 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29997253 UniProtKB:Q8N9N2 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29997253 UniProtKB:Q8N9N2-2 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29997253 UniProtKB:Q9H1I8 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P53701 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q8N9N2 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9H1I8 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:Q8N9N2 9606 Homo sapiens IntAct Activating signal cointegrator 1 complex subunit 3 20260425 UniProtKB Q8N3C0 ASCC3 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Activating signal cointegrator 1 complex subunit 3 20251115 UniProtKB Q8N3C0 ASCC3 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000304 TAS Reactome:R-HSA-9948299 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20251113 UniProtKB Q8N3C0 ASCC3 located_in GO:0005634 nucleus cellular_component ECO:0000269 EXP PMID:29144457 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20251027 UniProtKB Q8N3C0 ASCC3 located_in GO:0016607 nuclear speck cellular_component ECO:0000269 EXP PMID:29144457 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20251027 UniProtKB Q8N3C0 ASCC3 located_in GO:0016607 nuclear speck cellular_component ECO:0000269 EXP PMID:29997253 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20251027 UniProtKB Q8N3C0 ASCC3 enables GO:0016887 ATP hydrolysis activity molecular_function ECO:0000304 TAS Reactome:R-HSA-9948300 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20250608 UniProtKB Q8N3C0 ASCC3 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948291 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20250519 UniProtKB Q8N3C0 ASCC3 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948300 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20250519 UniProtKB Q8N3C0 ASCC3 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:29997253 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 complex subunit 3 20240823 UniProtKB Q8N3C0 ASCC3 involved_in GO:0006260 DNA replication biological_process ECO:0005547 NAS PMID:29997253 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 complex subunit 3 20240823 UniProtKB Q8N3C0 ASCC3 involved_in GO:0006307 DNA alkylation repair biological_process ECO:0005547 NAS PMID:29997253 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 complex subunit 3 20240823 UniProtKB Q8N3C0 ASCC3 involved_in GO:0032790 ribosome disassembly biological_process ECO:0005547 NAS PMID:32099016 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 complex subunit 3 20240823 UniProtKB Q8N3C0 ASCC3 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:32099016 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 complex subunit 3 20240823 UniProtKB Q8N3C0 ASCC3 part_of GO:1990391 DNA repair complex cellular_component ECO:0000353 IPI PMID:29997253 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 complex subunit 3 20240823 UniProtKB Q8N3C0 ASCC3 enables GO:0016887 ATP hydrolysis activity molecular_function ECO:0000314 IDA PMID:32579943 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 enables GO:0016887 ATP hydrolysis activity molecular_function ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 is_active_in GO:0022626 cytosolic ribosome cellular_component ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 involved_in GO:0032790 ribosome disassembly biological_process ECO:0000314 IDA PMID:32579943 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 involved_in GO:0032790 ribosome disassembly biological_process ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:32579943 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20230215 UniProtKB Q8N3C0 ASCC3 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000315 IMP PMID:32099016 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20210527 UniProtKB Q8N3C0 ASCC3 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:32099016 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20210527 UniProtKB Q8N3C0 ASCC3 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA PMID:28757607 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20210526 UniProtKB Q8N3C0 ASCC3 part_of GO:0180022 RQC-trigger complex cellular_component ECO:0000314 IDA PMID:12077347 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20160822 UniProtKB Q8N3C0 ASCC3 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:12077347 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20160526 UniProtKB Q8N3C0 ASCC3 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-112123 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20141212 UniProtKB Q8N3C0 ASCC3 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-112124 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20141212 UniProtKB Q8N3C0 ASCC3 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-112125 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20141212 UniProtKB Q8N3C0 ASCC3 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5657617 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20141212 UniProtKB Q8N3C0 ASCC3 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5657637 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20141212 UniProtKB Q8N3C0 ASCC3 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5657642 9606 Homo sapiens Reactome Activating signal cointegrator 1 complex subunit 3 20141212 UniProtKB Q8N3C0 ASCC3 located_in GO:0016020 membrane cellular_component ECO:0007005 HDA PMID:19946888 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20140627 UniProtKB Q8N3C0 ASCC3 enables GO:0003723 RNA binding molecular_function ECO:0007005 HDA PMID:22681889 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20140203 UniProtKB Q8N3C0 ASCC3 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22055184 UniProtKB:Q96Q83 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20120228 UniProtKB Q8N3C0 ASCC3 located_in GO:0005634 nucleus cellular_component ECO:0000304 TAS PMID:22055184 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20120228 UniProtKB Q8N3C0 ASCC3 involved_in GO:0006307 DNA alkylation repair biological_process ECO:0000314 IDA PMID:22055184 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20120228 UniProtKB Q8N3C0 ASCC3 enables GO:0043138 3'-5' DNA helicase activity molecular_function ECO:0000314 IDA PMID:22055184 9606 Homo sapiens UniProt Activating signal cointegrator 1 complex subunit 3 20120228