GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB O75787 ATP6AP2 is_active_in GO:0009897 external side of plasma membrane cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN001000649|UniProtKB:O75787 9606 Homo sapiens GO_Central Renin receptor 20231109 UniProtKB O75787 ATP6AP2 involved_in GO:0030177 positive regulation of Wnt signaling pathway biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1917745|PANTHER:PTN000331504|UniProtKB:O75787 9606 Homo sapiens GO_Central Renin receptor 20231109 UniProtKB O75787 ATP6AP2 located_in GO:0000421 autophagosome membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0022 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0005737 cytoplasm cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00026971 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0005765 lysosomal membrane cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:Q9CYN9|ensembl:ENSMUSP00000033313|UniProtKB-SubCell:SL-0157 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0097 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0010008 endosome membrane cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:Q9CYN9|ensembl:ENSMUSP00000033313|UniProtKB-SubCell:SL-0100 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0016020 membrane cellular_component ECO:0000256 IEA GO_REF:0000002 InterPro:IPR012493 9606 Homo sapiens InterPro Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0030424 axon cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0279 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0030665 clathrin-coated vesicle membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0071 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0030672 synaptic vesicle membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0260 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0032591 dendritic spine membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0285 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 enables GO:0038023 signaling receptor activity molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR012493 9606 Homo sapiens InterPro Renin receptor 20260428 UniProtKB O75787 ATP6AP2 located_in GO:0098588 bounding membrane of organelle cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027281 9606 Homo sapiens UniProt Renin receptor 20260428 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:O00526 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:O95183 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P21854 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P42857 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P53801 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q01453 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q16617 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q5BJF2 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q969S6 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q96IW7 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9NPL8 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:O00526 9606 Homo sapiens IntAct Renin receptor 20260425 UniProtKB O75787 ATP6AP2 involved_in GO:0021626 central nervous system maturation biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9CYN9|ensembl:ENSMUSP00000033313 9606 Homo sapiens Ensembl Renin receptor 20260422 UniProtKB O75787 ATP6AP2 involved_in GO:0030177 positive regulation of Wnt signaling pathway biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9CYN9|ensembl:ENSMUSP00000033313 9606 Homo sapiens Ensembl Renin receptor 20260422 UniProtKB O75787 ATP6AP2 involved_in GO:0097401 synaptic vesicle lumen acidification biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9CYN9|ensembl:ENSMUSP00000033313 9606 Homo sapiens Ensembl Renin receptor 20260422 UniProtKB O75787 ATP6AP2 located_in GO:0005765 lysosomal membrane cellular_component ECO:0000269 EXP PMID:29127204 9606 Homo sapiens UniProt Renin receptor 20251027 UniProtKB O75787 ATP6AP2 located_in GO:0010008 endosome membrane cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9CYN9 9606 Homo sapiens UniProt Renin receptor 20251027 UniProtKB O75787 ATP6AP2 located_in GO:0000139 Golgi membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 located_in GO:0005765 lysosomal membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 located_in GO:0005886 plasma membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:0007035 vacuolar acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:0007042 lysosomal lumen acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:0007042 lysosomal lumen acidification biological_process ECO:0005547 NAS PMID:33065002 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 located_in GO:0010008 endosome membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 located_in GO:0016020 membrane cellular_component ECO:0000314 IDA PMID:33065002 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 part_of GO:0033176 proton-transporting V-type ATPase complex cellular_component ECO:0005547 NAS PMID:33065002 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:0048388 endosomal lumen acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:0051452 intracellular pH reduction biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:0061795 Golgi lumen acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 involved_in GO:1902600 proton transmembrane transport biological_process ECO:0005547 NAS PMID:33065002 9606 Homo sapiens ComplexPortal Renin receptor 20240902 UniProtKB O75787 ATP6AP2 part_of GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:P81134 9606 Homo sapiens UniProt Renin receptor 20210916 UniProtKB O75787 ATP6AP2 part_of GO:0016471 vacuolar proton-transporting V-type ATPase complex cellular_component ECO:0000315 IMP PMID:30985297 9606 Homo sapiens UniProt Renin receptor 20201008 UniProtKB O75787 ATP6AP2 located_in GO:0005765 lysosomal membrane cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9CYN9 9606 Homo sapiens UniProt Renin receptor 20201005 UniProtKB O75787 ATP6AP2 located_in GO:0010008 endosome membrane cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9CYN9 9606 Homo sapiens UniProt Renin receptor 20201005 UniProtKB O75787 ATP6AP2 involved_in GO:0021626 central nervous system maturation biological_process ECO:0000315 IMP PMID:30985297 9606 Homo sapiens UniProt Renin receptor 20201001 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30374053 UniProtKB:P61421 9606 Homo sapiens UniProt Renin receptor 20200625 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30374053 UniProtKB:Q9P0T7 9606 Homo sapiens UniProt Renin receptor 20200625 UniProtKB O75787 ATP6AP2 involved_in GO:0090263 positive regulation of canonical Wnt signaling pathway biological_process ECO:0000315 IMP PMID:30374053 9606 Homo sapiens UniProt Renin receptor 20200625 UniProtKB O75787 ATP6AP2 involved_in GO:0007042 lysosomal lumen acidification biological_process ECO:0000315 IMP PMID:32276428 9606 Homo sapiens UniProt Renin receptor 20200422 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29127204 UniProtKB:Q15904 9606 Homo sapiens UniProt Renin receptor 20190606 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29127204 UniProtKB:Q3ZAQ7 9606 Homo sapiens UniProt Renin receptor 20190606 UniProtKB O75787 ATP6AP2 located_in GO:0005764 lysosome cellular_component ECO:0000314 IDA PMID:29127204 9606 Homo sapiens UniProt Renin receptor 20190606 UniProtKB O75787 ATP6AP2 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:29127204 9606 Homo sapiens UniProt Renin receptor 20190606 UniProtKB O75787 ATP6AP2 part_of GO:0016471 vacuolar proton-transporting V-type ATPase complex cellular_component ECO:0000315 IMP PMID:29127204 9606 Homo sapiens UniProt Renin receptor 20190606 UniProtKB O75787 ATP6AP2 located_in GO:0070821 tertiary granule membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-6798747 9606 Homo sapiens Reactome Renin receptor 20160716 UniProtKB O75787 ATP6AP2 located_in GO:0101003 ficolin-1-rich granule membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-6800426 9606 Homo sapiens Reactome Renin receptor 20160716 UniProtKB O75787 ATP6AP2 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:23533145 9606 Homo sapiens UniProt Renin receptor 20140714 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20093472 UniProtKB:O75581 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20093472 UniProtKB:P27449 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20093472 UniProtKB:P61421 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 involved_in GO:0021903 rostrocaudal neural tube patterning biological_process ECO:0000315 IMP PMID:20093472 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 involved_in GO:0030177 positive regulation of Wnt signaling pathway biological_process ECO:0000315 IMP PMID:20093472 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 involved_in GO:0048069 eye pigmentation biological_process ECO:0000315 IMP PMID:20093472 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 involved_in GO:0060323 head morphogenesis biological_process ECO:0000315 IMP PMID:20093472 9606 Homo sapiens UniProt Renin receptor 20140528 UniProtKB O75787 ATP6AP2 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19199708 9606 Homo sapiens UniProt Renin receptor 20131029 UniProtKB O75787 ATP6AP2 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19056867 9606 Homo sapiens UniProt Renin receptor 20131024 UniProtKB O75787 ATP6AP2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-2022403 9606 Homo sapiens Reactome Renin receptor 20130528 UniProtKB O75787 ATP6AP2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-2065357 9606 Homo sapiens Reactome Renin receptor 20130528 UniProtKB O75787 ATP6AP2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-6798747 9606 Homo sapiens Reactome Renin receptor 20130528 UniProtKB O75787 ATP6AP2 located_in GO:0005886 plasma membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-6800426 9606 Homo sapiens Reactome Renin receptor 20130528 UniProtKB O75787 ATP6AP2 involved_in GO:0032914 positive regulation of transforming growth factor beta1 production biological_process ECO:0000314 IDA PMID:16374430 9606 Homo sapiens HGNC-UCL Renin receptor 20070306 UniProtKB O75787 ATP6AP2 involved_in GO:0002003 angiotensin maturation biological_process ECO:0000314 IDA PMID:15746149 9606 Homo sapiens HGNC-UCL Renin receptor 20070129 UniProtKB O75787 ATP6AP2 located_in GO:0009897 external side of plasma membrane cellular_component ECO:0000314 IDA PMID:15746149 9606 Homo sapiens HGNC-UCL Renin receptor 20070129 UniProtKB O75787 ATP6AP2 involved_in GO:0043408 regulation of MAPK cascade biological_process ECO:0000314 IDA PMID:15746149 9606 Homo sapiens HGNC-UCL Renin receptor 20070129 UniProtKB O75787 ATP6AP2 involved_in GO:0002003 angiotensin maturation biological_process ECO:0000314 IDA PMID:12045255 9606 Homo sapiens HGNC-UCL Renin receptor 20070105 UniProtKB O75787 ATP6AP2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12045255 UniProtKB:P00797 9606 Homo sapiens HGNC-UCL Renin receptor 20070105 UniProtKB O75787 ATP6AP2 located_in GO:0009897 external side of plasma membrane cellular_component ECO:0000314 IDA PMID:12045255 9606 Homo sapiens HGNC-UCL Renin receptor 20070105 UniProtKB O75787 ATP6AP2 involved_in GO:0043408 regulation of MAPK cascade biological_process ECO:0000314 IDA PMID:12045255 9606 Homo sapiens HGNC-UCL Renin receptor 20070105