GENE PRODUCT DB	GENE PRODUCT ID	SYMBOL	QUALIFIER	GO TERM	GO NAME	GO ASPECT	ECO ID	GO EVIDENCE CODE	REFERENCE	WITH/FROM	TAXON ID	TAXON NAME	ASSIGNED BY	GENE NAME	DATE
UniProtKB	Q9Y487	ATP6V0A2	part_of	GO:0016471	vacuolar proton-transporting V-type ATPase complex	cellular_component	ECO:0000318	IBA	GO_REF:0000033	MGI:MGI:2153480|PANTHER:PTN000179505|SGD:S000004658|SGD:S000005796|UniProtKB:Q29466|UniProtKB:Q9HBG4|WB:WBGene00006768|WB:WBGene00006914|WB:WBGene00006915|dictyBase:DDB_G0291858	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 2	20250902
UniProtKB	Q9Y487	ATP6V0A2	contributes_to	GO:0046961	proton-transporting ATPase activity, rotational mechanism	molecular_function	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN000179505|SGD:S000004658|SGD:S000005796|dictyBase:DDB_G0291858	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 2	20250415
UniProtKB	Q9Y487	ATP6V0A2	is_active_in	GO:0005886	plasma membrane	cellular_component	ECO:0000318	IBA	GO_REF:0000033	FB:FBgn0028670|MGI:MGI:1350931|MGI:MGI:2153480|PANTHER:PTN000907964|RGD:1305055|UniProtKB:Q13488|UniProtKB:Q93050|UniProtKB:Q9HBG4|UniProtKB:Q9Y487|WB:WBGene00006914|WB:WBGene00006915	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 2	20220414
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:0007035	vacuolar acidification	biological_process	ECO:0000318	IBA	GO_REF:0000033	CGD:CAL0000191982|PANTHER:PTN000179505|SGD:S000004658|SGD:S000005796	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 2	20170228
UniProtKB	Q9Y487	ATP6V0A2	enables	GO:0051117	ATPase binding	molecular_function	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN000179505|UniProtKB:Q93050|UniProtKB:Q9HBG4	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 2	20170228
UniProtKB	Q9Y487	ATP6V0A2	part_of	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain	cellular_component	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR026028	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 2	20260428
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0005886	plasma membrane	cellular_component	ECO:0007322	IEA	GO_REF:0000044	UniProtKB-SubCell:SL-0039	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 2	20260428
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0007322	IEA	GO_REF:0000044	UniProtKB-SubCell:SL-0100	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 2	20260428
UniProtKB	Q9Y487	ATP6V0A2	part_of	GO:0033179	proton-transporting V-type ATPase, V0 domain	cellular_component	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:P15920|ensembl:ENSMUSP00000039737|InterPro:IPR002490	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 2	20260428
UniProtKB	Q9Y487	ATP6V0A2	enables	GO:0046961	proton-transporting ATPase activity, rotational mechanism	molecular_function	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR002490|InterPro:IPR026028	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 2	20260428
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:1902600	proton transmembrane transport	biological_process	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR002490	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 2	20260428
UniProtKB	Q9Y487	ATP6V0A2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:16415858	UniProtKB:Q99418	9606	Homo sapiens	IntAct	V-type proton ATPase 116 kDa subunit a 2	20260425
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0001669	acrosomal vesicle	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:P15920|ensembl:ENSMUSP00000039737	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 2	20260422
UniProtKB	Q9Y487	ATP6V0A2	contributes_to	GO:0015078	proton transmembrane transporter activity	molecular_function	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:P15920|ensembl:ENSMUSP00000039737	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 2	20260422
UniProtKB	Q9Y487	ATP6V0A2	part_of	GO:0033176	proton-transporting V-type ATPase complex	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:P15920|ensembl:ENSMUSP00000039737	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 2	20260422
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0048471	perinuclear region of cytoplasm	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:P15920|ensembl:ENSMUSP00000039737	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 2	20260422
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0005886	plasma membrane	cellular_component	ECO:0000314	IDA	GO_REF:0000052		9606	Homo sapiens	HPA	V-type proton ATPase 116 kDa subunit a 2	20251115
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0000139	Golgi membrane	cellular_component	ECO:0005547	NAS	PMID:32001091		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 2	20240902
UniProtKB	Q9Y487	ATP6V0A2	part_of	GO:0033176	proton-transporting V-type ATPase complex	cellular_component	ECO:0005547	NAS	PMID:33065002		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 2	20240902
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:0061795	Golgi lumen acidification	biological_process	ECO:0005547	NAS	PMID:32001091		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 2	20240902
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:1902600	proton transmembrane transport	biological_process	ECO:0005547	NAS	PMID:33065002		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 2	20240902
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:0006879	intracellular iron ion homeostasis	biological_process	ECO:0000315	IMP	PMID:28296633		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 2	20170626
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:0036295	cellular response to increased oxygen levels	biological_process	ECO:0000315	IMP	PMID:28296633		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 2	20170626
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:0016241	regulation of macroautophagy	biological_process	ECO:0000303	NAS	PMID:22982048		9606	Homo sapiens	ParkinsonsUK-UCL	V-type proton ATPase 116 kDa subunit a 2	20160215
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0005765	lysosomal membrane	cellular_component	ECO:0007005	HDA	PMID:17897319		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 2	20130924
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0030670	phagocytic vesicle membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-1222516		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 2	20110228
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-5252133		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 2	20100712
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-74723		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 2	20100712
UniProtKB	Q9Y487	ATP6V0A2	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-917841		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 2	20100712
UniProtKB	Q9Y487	ATP6V0A2	involved_in	GO:0006955	immune response	biological_process	ECO:0000304	TAS	PMID:2247090		9606	Homo sapiens	PINC	V-type proton ATPase 116 kDa subunit a 2	20030904