GENE PRODUCT DB	GENE PRODUCT ID	SYMBOL	QUALIFIER	GO TERM	GO NAME	GO ASPECT	ECO ID	GO EVIDENCE CODE	REFERENCE	WITH/FROM	TAXON ID	TAXON NAME	ASSIGNED BY	GENE NAME	DATE
UniProtKB	Q9HBG4	ATP6V0A4	part_of	GO:0016471	vacuolar proton-transporting V-type ATPase complex	cellular_component	ECO:0000318	IBA	GO_REF:0000033	MGI:MGI:2153480|PANTHER:PTN000179505|SGD:S000004658|SGD:S000005796|UniProtKB:Q29466|UniProtKB:Q9HBG4|WB:WBGene00006768|WB:WBGene00006914|WB:WBGene00006915|dictyBase:DDB_G0291858	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 4	20250902
UniProtKB	Q9HBG4	ATP6V0A4	contributes_to	GO:0046961	proton-transporting ATPase activity, rotational mechanism	molecular_function	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN000179505|SGD:S000004658|SGD:S000005796|dictyBase:DDB_G0291858	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 4	20250415
UniProtKB	Q9HBG4	ATP6V0A4	is_active_in	GO:0005886	plasma membrane	cellular_component	ECO:0000318	IBA	GO_REF:0000033	FB:FBgn0028670|MGI:MGI:1350931|MGI:MGI:2153480|PANTHER:PTN000907964|RGD:1305055|UniProtKB:Q13488|UniProtKB:Q93050|UniProtKB:Q9HBG4|UniProtKB:Q9Y487|WB:WBGene00006914|WB:WBGene00006915	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 4	20220414
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0007035	vacuolar acidification	biological_process	ECO:0000318	IBA	GO_REF:0000033	CGD:CAL0000191982|PANTHER:PTN000179505|SGD:S000004658|SGD:S000005796	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 4	20170228
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0051117	ATPase binding	molecular_function	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN000179505|UniProtKB:Q93050|UniProtKB:Q9HBG4	9606	Homo sapiens	GO_Central	V-type proton ATPase 116 kDa subunit a 4	20170228
UniProtKB	Q9HBG4	ATP6V0A4	part_of	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain	cellular_component	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR026028	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 4	20260428
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0016323	basolateral plasma membrane	cellular_component	ECO:0007322	IEA	GO_REF:0000044	UniProtKB-SubCell:SL-0026	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20260428
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0016324	apical plasma membrane	cellular_component	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:D4A1H0|ensembl:ENSRNOP00000061018|UniProtKB:Q920R6|ensembl:ENSMUSP00000039381|UniProtKB-SubCell:SL-0015	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20260428
UniProtKB	Q9HBG4	ATP6V0A4	part_of	GO:0033179	proton-transporting V-type ATPase, V0 domain	cellular_component	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR002490	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 4	20260428
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0046961	proton-transporting ATPase activity, rotational mechanism	molecular_function	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR002490|InterPro:IPR026028	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 4	20260428
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:1902600	proton transmembrane transport	biological_process	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR002490	9606	Homo sapiens	InterPro	V-type proton ATPase 116 kDa subunit a 4	20260428
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32814053	UniProtKB:P02649	9606	Homo sapiens	IntAct	V-type proton ATPase 116 kDa subunit a 4	20260425
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0005768	endosome	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q920R6|ensembl:ENSMUSP00000039381	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 4	20260422
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0005903	brush border	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q920R6|ensembl:ENSMUSP00000039381	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 4	20260422
UniProtKB	Q9HBG4	ATP6V0A4	part_of	GO:0016471	vacuolar proton-transporting V-type ATPase complex	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q920R6|ensembl:ENSMUSP00000039381	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 4	20260422
UniProtKB	Q9HBG4	ATP6V0A4	is_active_in	GO:0030672	synaptic vesicle membrane	cellular_component	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:D4A1H0|ensembl:ENSRNOP00000061018	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 4	20260422
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0045177	apical part of cell	cellular_component	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:D4A1H0|ensembl:ENSRNOP00000061018|UniProtKB:Q920R6|ensembl:ENSMUSP00000039381	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20260422
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0097401	synaptic vesicle lumen acidification	biological_process	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q920R6|ensembl:ENSMUSP00000039381	9606	Homo sapiens	Ensembl	V-type proton ATPase 116 kDa subunit a 4	20260422
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0005886	plasma membrane	cellular_component	ECO:0005547	NAS	PMID:32001091		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 4	20240902
UniProtKB	Q9HBG4	ATP6V0A4	part_of	GO:0033176	proton-transporting V-type ATPase complex	cellular_component	ECO:0005547	NAS	PMID:33065002		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 4	20240902
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0051452	intracellular pH reduction	biological_process	ECO:0005547	NAS	PMID:32001091		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 4	20240902
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:1902600	proton transmembrane transport	biological_process	ECO:0005547	NAS	PMID:33065002		9606	Homo sapiens	ComplexPortal	V-type proton ATPase 116 kDa subunit a 4	20240902
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0016323	basolateral plasma membrane	cellular_component	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q920R6	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20211209
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0097254	renal tubular secretion	biological_process	ECO:0000315	IMP	PMID:12414817		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20211117
UniProtKB	Q9HBG4	ATP6V0A4	part_of	GO:0016471	vacuolar proton-transporting V-type ATPase complex	cellular_component	ECO:0000314	IDA	PMID:10973252		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20210429
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0070062	extracellular exosome	cellular_component	ECO:0007005	HDA	PMID:19199708		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20131029
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0070062	extracellular exosome	cellular_component	ECO:0007005	HDA	PMID:19056867		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20131024
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0005765	lysosomal membrane	cellular_component	ECO:0007005	HDA	PMID:17897319		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20130924
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0030670	phagocytic vesicle membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-1222516		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 4	20110228
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-5252133		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 4	20100712
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-74723		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 4	20100712
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0010008	endosome membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-917841		9606	Homo sapiens	Reactome	V-type proton ATPase 116 kDa subunit a 4	20100712
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0045177	apical part of cell	cellular_component	ECO:0000314	IDA	PMID:14675051		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090612
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0005768	endosome	cellular_component	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q920R6	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090608
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0016324	apical plasma membrane	cellular_component	ECO:0000314	IDA	PMID:15800125		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090605
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0005886	plasma membrane	cellular_component	ECO:0000314	IDA	PMID:17360703		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090603
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0016324	apical plasma membrane	cellular_component	ECO:0000314	IDA	PMID:12649290		9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090603
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0051117	ATPase binding	molecular_function	ECO:0000353	IPI	PMID:17360703	UniProtKB:O75348	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090603
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0051117	ATPase binding	molecular_function	ECO:0000353	IPI	PMID:17360703	UniProtKB:Q96LB4	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090603
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:18632794	UniProtKB:P47859	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090428
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:18632794	UniProtKB:P00511	9606	Homo sapiens	UniProt	V-type proton ATPase 116 kDa subunit a 4	20090424
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:1902600	proton transmembrane transport	biological_process	ECO:0000315	IMP	PMID:10973252		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061024
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0001503	ossification	biological_process	ECO:0000315	IMP	PMID:10973252		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:12649290	UniProtKB:P00511	9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:12649290	UniProtKB:P08237	9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0006885	regulation of pH	biological_process	ECO:0000315	IMP	PMID:10973252		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	involved_in	GO:0007605	sensory perception of sound	biological_process	ECO:0000315	IMP	PMID:12414817		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0016324	apical plasma membrane	cellular_component	ECO:0000314	IDA	PMID:10973252		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0031526	brush border membrane	cellular_component	ECO:0000314	IDA	PMID:14638902		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012
UniProtKB	Q9HBG4	ATP6V0A4	located_in	GO:0045177	apical part of cell	cellular_component	ECO:0000314	IDA	PMID:14638902		9606	Homo sapiens	HGNC-UCL	V-type proton ATPase 116 kDa subunit a 4	20061012