GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q99437 ATP6V0B is_active_in GO:0016020 membrane cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0028662|FB:FBgn0262736|MGI:MGI:1890510|MGI:MGI:88116|PANTHER:PTN000813763|RGD:621394|SGD:S000000753|SGD:S000001068|SGD:S000006155|UniProtKB:P23956|UniProtKB:P27449|UniProtKB:Q2TA24|UniProtKB:Q99437|dictyBase:DDB_G0274381 9606 Homo sapiens GO_Central V-type proton ATPase 21 kDa proteolipid subunit c'' 20250902 UniProtKB Q99437 ATP6V0B involved_in GO:0006811 monoatomic ion transport biological_process ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0406 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B enables GO:0015078 proton transmembrane transporter activity molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:Q91V37|ensembl:ENSMUSP00000047682|InterPro:IPR002379 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B located_in GO:0030665 clathrin-coated vesicle membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0071 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B located_in GO:0031410 cytoplasmic vesicle cellular_component ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0968 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B part_of GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain cellular_component ECO:0000256 IEA GO_REF:0000002 InterPro:IPR002379 9606 Homo sapiens InterPro V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B part_of GO:0033179 proton-transporting V-type ATPase, V0 domain cellular_component ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000245 9606 Homo sapiens InterPro V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B enables GO:0046961 proton-transporting ATPase activity, rotational mechanism molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000245 9606 Homo sapiens InterPro V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B involved_in GO:1902600 proton transmembrane transport biological_process ECO:0000501 IEA GO_REF:0000120 InterPro:IPR000245|InterPro:IPR002379|UniProtKB-KW:KW-0375 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20251006 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23864651 UniProtKB:P43220 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:O15529 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P05090 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P22732 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P26715 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P27105 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P29400-2 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P30301 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P48165 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P54849 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q14973 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q3ZAQ7 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q86Y34 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8IXM6 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q96DZ7 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q96HJ5 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q96KR6 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9BZJ8 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9GZY8-5 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9HBV2 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9NWH2 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9Y5U4 9606 Homo sapiens IntAct V-type proton ATPase 21 kDa proteolipid subunit c'' 20251004 UniProtKB Q99437 ATP6V0B located_in GO:0005768 endosome cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91V37|ensembl:ENSMUSP00000047682 9606 Homo sapiens Ensembl V-type proton ATPase 21 kDa proteolipid subunit c'' 20250926 UniProtKB Q99437 ATP6V0B located_in GO:0016020 membrane cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00028763|UniProtKB:Q91V37|ensembl:ENSMUSP00000047682 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20250926 UniProtKB Q99437 ATP6V0B part_of GO:0033176 proton-transporting V-type ATPase complex cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91V37|ensembl:ENSMUSP00000047682 9606 Homo sapiens Ensembl V-type proton ATPase 21 kDa proteolipid subunit c'' 20250926 UniProtKB Q99437 ATP6V0B located_in GO:0000139 Golgi membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B located_in GO:0005886 plasma membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:0007035 vacuolar acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:0007042 lysosomal lumen acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:0007042 lysosomal lumen acidification biological_process ECO:0005547 NAS PMID:33065002 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B located_in GO:0010008 endosome membrane cellular_component ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B located_in GO:0016020 membrane cellular_component ECO:0000314 IDA PMID:33065002 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B part_of GO:0033176 proton-transporting V-type ATPase complex cellular_component ECO:0005547 NAS PMID:33065002 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:0048388 endosomal lumen acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:0051452 intracellular pH reduction biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:0061795 Golgi lumen acidification biological_process ECO:0005547 NAS PMID:32001091 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B involved_in GO:1902600 proton transmembrane transport biological_process ECO:0005547 NAS PMID:33065002 9606 Homo sapiens ComplexPortal V-type proton ATPase 21 kDa proteolipid subunit c'' 20240902 UniProtKB Q99437 ATP6V0B enables GO:0046961 proton-transporting ATPase activity, rotational mechanism molecular_function ECO:0000304 TAS PMID:9653649 9606 Homo sapiens PINC V-type proton ATPase 21 kDa proteolipid subunit c'' 20220207 UniProtKB Q99437 ATP6V0B part_of GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q2TA24 9606 Homo sapiens UniProt V-type proton ATPase 21 kDa proteolipid subunit c'' 20210916 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9639286 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9640167 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9640168 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9640175 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9640195 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9645598 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9645608 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9646468 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B located_in GO:0005765 lysosomal membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9858940 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20190323 UniProtKB Q99437 ATP6V0B involved_in GO:0016241 regulation of macroautophagy biological_process ECO:0000303 NAS PMID:22982048 9606 Homo sapiens ParkinsonsUK-UCL V-type proton ATPase 21 kDa proteolipid subunit c'' 20160215 UniProtKB Q99437 ATP6V0B located_in GO:0030670 phagocytic vesicle membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-1222516 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20110228 UniProtKB Q99437 ATP6V0B located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-5252133 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20100712 UniProtKB Q99437 ATP6V0B located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-74723 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20100712 UniProtKB Q99437 ATP6V0B located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-917841 9606 Homo sapiens Reactome V-type proton ATPase 21 kDa proteolipid subunit c'' 20100712 UniProtKB Q99437 ATP6V0B located_in GO:0016020 membrane cellular_component ECO:0000304 TAS PMID:9653649 9606 Homo sapiens PINC V-type proton ATPase 21 kDa proteolipid subunit c'' 20030904 UniProtKB Q99437 ATP6V0B involved_in GO:1902600 proton transmembrane transport biological_process ECO:0000304 TAS PMID:9653649 9606 Homo sapiens PINC V-type proton ATPase 21 kDa proteolipid subunit c'' 20030904