GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB P15313 ATP6V1B1 involved_in GO:1902600 proton transmembrane transport biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0005671|MGI:MGI:103285|MGI:MGI:109618|PANTHER:PTN000389697|SGD:S000000331|UniProtKB:P15313 9606 Homo sapiens GO_Central V-type proton ATPase subunit B, kidney isoform 20250904 UniProtKB P15313 ATP6V1B1 part_of GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000389697|RGD:620284|SGD:S000000331|UniProtKB:P15313|UniProtKB:P21281|UniProtKB:P31408 9606 Homo sapiens GO_Central V-type proton ATPase subunit B, kidney isoform 20250624 UniProtKB P15313 ATP6V1B1 is_active_in GO:0005886 plasma membrane cellular_component ECO:0000318 IBA GO_REF:0000033 CGD:CAL0000199755|FB:FBgn0005671|MGI:MGI:103285|MGI:MGI:109618|PANTHER:PTN000389697|RGD:1310619|UniProtKB:P15313|UniProtKB:P21281 9606 Homo sapiens GO_Central V-type proton ATPase subunit B, kidney isoform 20250624 UniProtKB P15313 ATP6V1B1 is_active_in GO:0016324 apical plasma membrane cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:103285|MGI:MGI:109618|PANTHER:PTN000389708|RGD:1310619|UniProtKB:P15313|UniProtKB:P21281 9606 Homo sapiens GO_Central V-type proton ATPase subunit B, kidney isoform 20250624 UniProtKB P15313 ATP6V1B1 involved_in GO:0007035 vacuolar acidification biological_process ECO:0000318 IBA GO_REF:0000033 CGD:CAL0000199755|FB:FBgn0005671|PANTHER:PTN000389698|SGD:S000000331 9606 Homo sapiens GO_Central V-type proton ATPase subunit B, kidney isoform 20220223 UniProtKB P15313 ATP6V1B1 part_of GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00090169 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 enables GO:0005524 ATP binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000194|InterPro:IPR020003 9606 Homo sapiens InterPro V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 located_in GO:0016323 basolateral plasma membrane cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:D3ZZS8|ensembl:ENSRNOP00000018302|UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431|UniProtKB-SubCell:SL-0026 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 located_in GO:0016324 apical plasma membrane cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:D3ZZS8|ensembl:ENSRNOP00000018302|UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431|UniProtKB-SubCell:SL-0015 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 part_of GO:0033180 proton-transporting V-type ATPase, V1 domain cellular_component ECO:0000256 IEA GO_REF:0000002 InterPro:IPR005723 9606 Homo sapiens InterPro V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 involved_in GO:0046034 ATP metabolic process biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR004100 9606 Homo sapiens InterPro V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 enables GO:0046961 proton-transporting ATPase activity, rotational mechanism molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR005723 9606 Homo sapiens InterPro V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 involved_in GO:1902600 proton transmembrane transport biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00027610|UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431|InterPro:IPR004100|InterPro:IPR005723 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20260601 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O14901 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O60333-2 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O75190-2 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O76024 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P02766 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P04792 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P46379-2 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q13148 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9Y3C5 9606 Homo sapiens IntAct V-type proton ATPase subunit B, kidney isoform 20260530 UniProtKB P15313 ATP6V1B1 located_in GO:0005737 cytoplasm cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 located_in GO:0005902 microvillus cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 enables GO:0015078 proton transmembrane transporter activity molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 located_in GO:0016020 membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 located_in GO:0016328 lateral plasma membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 enables GO:0044877 protein-containing complex binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:D3ZZS8|ensembl:ENSRNOP00000018302 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 involved_in GO:0097401 synaptic vesicle lumen acidification biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q91YH6|ensembl:ENSMUSP00000006431 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 is_active_in GO:0098850 extrinsic component of synaptic vesicle membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:D3ZZS8|ensembl:ENSRNOP00000018302 9606 Homo sapiens Ensembl V-type proton ATPase subunit B, kidney isoform 20260529 UniProtKB P15313 ATP6V1B1 located_in GO:0016323 basolateral plasma membrane cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q91YH6 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20240313 UniProtKB P15313 ATP6V1B1 involved_in GO:0097254 renal tubular secretion biological_process ECO:0000315 IMP PMID:12414817 9606 Homo sapiens HGNC-UCL V-type proton ATPase subunit B, kidney isoform 20211117 UniProtKB P15313 ATP6V1B1 part_of GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain cellular_component ECO:0000314 IDA PMID:33065002 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20210318 UniProtKB P15313 ATP6V1B1 located_in GO:0016324 apical plasma membrane cellular_component ECO:0000314 IDA PMID:16769747 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20210318 UniProtKB P15313 ATP6V1B1 located_in GO:0016324 apical plasma membrane cellular_component ECO:0000314 IDA PMID:29993276 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20210318 UniProtKB P15313 ATP6V1B1 involved_in GO:0045851 pH reduction biological_process ECO:0000315 IMP PMID:16769747 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20210318 UniProtKB P15313 ATP6V1B1 involved_in GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly biological_process ECO:0000315 IMP PMID:16769747 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20210318 UniProtKB P15313 ATP6V1B1 involved_in GO:1902600 proton transmembrane transport biological_process ECO:0000315 IMP PMID:16769747 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20210318 UniProtKB P15313 ATP6V1B1 involved_in GO:0016241 regulation of macroautophagy biological_process ECO:0000303 NAS PMID:22982048 9606 Homo sapiens ParkinsonsUK-UCL V-type proton ATPase subunit B, kidney isoform 20160215 UniProtKB P15313 ATP6V1B1 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:23533145 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20140714 UniProtKB P15313 ATP6V1B1 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19199708 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20131029 UniProtKB P15313 ATP6V1B1 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19056867 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20131024 UniProtKB P15313 ATP6V1B1 located_in GO:0005737 cytoplasm cellular_component ECO:0000250 ISS PMID:14585495 UniProtKB:Q91YH6 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20120228 UniProtKB P15313 ATP6V1B1 located_in GO:0005902 microvillus cellular_component ECO:0000250 ISS PMID:14585495 UniProtKB:Q91YH6 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20120228 UniProtKB P15313 ATP6V1B1 located_in GO:0016323 basolateral plasma membrane cellular_component ECO:0000250 ISS PMID:14585495 UniProtKB:Q91YH6 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20120228 UniProtKB P15313 ATP6V1B1 located_in GO:0016328 lateral plasma membrane cellular_component ECO:0000250 ISS PMID:14585495 UniProtKB:Q91YH6 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20120228 UniProtKB P15313 ATP6V1B1 enables GO:0015078 proton transmembrane transporter activity molecular_function ECO:0000250 ISS PMID:14585495 UniProtKB:Q91YH6 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20110301 UniProtKB P15313 ATP6V1B1 involved_in GO:0042472 inner ear morphogenesis biological_process ECO:0000315 IMP PMID:19639346 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20110301 UniProtKB P15313 ATP6V1B1 involved_in GO:0007605 sensory perception of sound biological_process ECO:0000315 IMP PMID:20622307 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20110228 UniProtKB P15313 ATP6V1B1 involved_in GO:0045851 pH reduction biological_process ECO:0000315 IMP PMID:20622307 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20110228 UniProtKB P15313 ATP6V1B1 involved_in GO:0055074 calcium ion homeostasis biological_process ECO:0000315 IMP PMID:20622307 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20110228 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1222516 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-5252133 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-74723 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-917841 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9639286 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9640167 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9640168 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9640175 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9640195 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9645598 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9645608 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9646468 9606 Homo sapiens Reactome V-type proton ATPase subunit B, kidney isoform 20100712 UniProtKB P15313 ATP6V1B1 located_in GO:0016324 apical plasma membrane cellular_component ECO:0000314 IDA PMID:16928804 9606 Homo sapiens UniProt V-type proton ATPase subunit B, kidney isoform 20100514 UniProtKB P15313 ATP6V1B1 involved_in GO:0001503 ossification biological_process ECO:0000315 IMP PMID:16433694 9606 Homo sapiens HGNC-UCL V-type proton ATPase subunit B, kidney isoform 20061012 UniProtKB P15313 ATP6V1B1 involved_in GO:0006885 regulation of pH biological_process ECO:0000315 IMP PMID:12414817 9606 Homo sapiens HGNC-UCL V-type proton ATPase subunit B, kidney isoform 20061012 UniProtKB P15313 ATP6V1B1 part_of GO:0016471 vacuolar proton-transporting V-type ATPase complex cellular_component ECO:0000315 IMP PMID:12414817 9606 Homo sapiens HGNC-UCL V-type proton ATPase subunit B, kidney isoform 20061012 UniProtKB P15313 ATP6V1B1 involved_in GO:1902600 proton transmembrane transport biological_process ECO:0000315 IMP PMID:12414817 9606 Homo sapiens HGNC-UCL V-type proton ATPase subunit B, kidney isoform 20061012 UniProtKB P15313 ATP6V1B1 acts_upstream_of_or_within GO:0006885 regulation of pH biological_process ECO:0000315 IMP PMID:9916796 9606 Homo sapiens MGI V-type proton ATPase subunit B, kidney isoform 20060106 UniProtKB P15313 ATP6V1B1 acts_upstream_of_or_within GO:0007605 sensory perception of sound biological_process ECO:0000315 IMP PMID:9916796 9606 Homo sapiens MGI V-type proton ATPase subunit B, kidney isoform 20060106