GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q9NR09 BIRC6 is_active_in GO:0005802 trans-Golgi network cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN001295674|UniProtKB:Q9NR09 9606 Homo sapiens GO_Central Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20240606 UniProtKB Q9NR09 BIRC6 enables GO:0061631 ubiquitin conjugating enzyme activity molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0266717|MGI:MGI:1276108|MGI:MGI:1343160|PANTHER:PTN008183954|UniProtKB:Q9C0C9 9606 Homo sapiens GO_Central Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20240606 UniProtKB Q9NR09 BIRC6 involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0266717|MGI:MGI:1276108|PANTHER:PTN000799330|UniProtKB:Q9NR09 9606 Homo sapiens GO_Central Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20211113 UniProtKB Q9NR09 BIRC6 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000799330|UniProtKB:Q9H832 9606 Homo sapiens GO_Central Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20200810 UniProtKB Q9NR09 BIRC6 located_in GO:0000922 spindle pole cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0448 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026878|InterPro:IPR022103 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0004869 cysteine-type endopeptidase inhibitor activity molecular_function ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0789 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 located_in GO:0005768 endosome cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0101 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 located_in GO:0005794 Golgi apparatus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0132 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 located_in GO:0005813 centrosome cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0048 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 involved_in GO:0006915 apoptotic process biological_process ECO:0000501 IEA GO_REF:0000120 InterPro:IPR022103|UniProtKB-KW:KW-0053 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027966 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0016740 transferase activity molecular_function ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0808 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0030414 peptidase inhibitor activity molecular_function ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0646 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 involved_in GO:0032465 regulation of cytokinesis biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR022103 9606 Homo sapiens InterPro Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 involved_in GO:0042127 regulation of cell population proliferation biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027546 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027746 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0046872 metal ion binding molecular_function ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0479 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 involved_in GO:0051301 cell division biological_process ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0132 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0061631 ubiquitin conjugating enzyme activity molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:O88738|ensembl:ENSMUSP00000138333|EC:2.3.2.24 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 located_in GO:0090543 Flemming body cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0490 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260105 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:P53350 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:Q02241 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:Q02750 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:Q96A65 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26496610 UniProtKB:P53350 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q86UB9 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q8ND61 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q99996 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9H1P3 9606 Homo sapiens IntAct Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20260103 UniProtKB Q9NR09 BIRC6 involved_in GO:0001890 placenta development biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:O88738|ensembl:ENSMUSP00000138333 9606 Homo sapiens Ensembl Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20251226 UniProtKB Q9NR09 BIRC6 located_in GO:0016020 membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:O88738|ensembl:ENSMUSP00000138333 9606 Homo sapiens Ensembl Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20251226 UniProtKB Q9NR09 BIRC6 located_in GO:0005794 Golgi apparatus cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20251115 UniProtKB Q9NR09 BIRC6 located_in GO:0072686 mitotic spindle cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20251115 UniProtKB Q9NR09 BIRC6 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9700131 9606 Homo sapiens Reactome Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20210126 UniProtKB Q9NR09 BIRC6 located_in GO:0016020 membrane cellular_component ECO:0007005 HDA PMID:19946888 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20140627 UniProtKB Q9NR09 BIRC6 involved_in GO:2001237 negative regulation of extrinsic apoptotic signaling pathway biological_process ECO:0000315 IMP PMID:14765125 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20130607 UniProtKB Q9NR09 BIRC6 located_in GO:0000922 spindle pole cellular_component ECO:0000314 IDA PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000314 IDA PMID:15200957 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0004869 cysteine-type endopeptidase inhibitor activity molecular_function ECO:0000315 IMP PMID:15200957 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15200957 UniProtKB:O43464 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15200957 UniProtKB:Q9NR28 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:O60645 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:P40818 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:P61006 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18329369 UniProtKB:P62491 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 located_in GO:0005768 endosome cellular_component ECO:0000314 IDA PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 located_in GO:0005802 trans-Golgi network cellular_component ECO:0000314 IDA PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 located_in GO:0005815 microtubule organizing center cellular_component ECO:0000314 IDA PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 involved_in GO:0006468 protein phosphorylation biological_process ECO:0000304 TAS PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000304 TAS PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 located_in GO:0030496 midbody cellular_component ECO:0000314 IDA PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 involved_in GO:0032465 regulation of cytokinesis biological_process ECO:0000315 IMP PMID:18329369 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000315 IMP PMID:15200957 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120130 UniProtKB Q9NR09 BIRC6 involved_in GO:0042127 regulation of cell population proliferation biological_process ECO:0000304 TAS PMID:18414036 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20120126 UniProtKB Q9NR09 BIRC6 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14765125 UniProtKB:Q9H4P4 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20100608 UniProtKB Q9NR09 BIRC6 involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000304 TAS PMID:10544019 9606 Homo sapiens UniProt Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 20010815