GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB P02489 CRYAA involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:88515|MGI:MGI:88516|MGI:MGI:96240|PANTHER:PTN002264124|RGD:2414|RGD:621554|UniProtKB:P02489|UniProtKB:P02511 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20241121 UniProtKB P02489 CRYAA is_active_in GO:0005737 cytoplasm cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001223|FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|FB:FBgn0011296|FB:FBgn0031037|MGI:MGI:88515|MGI:MGI:88516|MGI:MGI:96240|PANTHER:PTN000897708|RGD:2414|RGD:61306|UniProtKB:O14558|UniProtKB:P02470|UniProtKB:P02489|UniProtKB:P02511|UniProtKB:P04792|UniProtKB:Q00649|UniProtKB:Q16082|WB:WBGene00002011|WB:WBGene00002013|WB:WBGene00002015|WB:WBGene00002016|WB:WBGene00002023|WB:WBGene00004798|ZFIN:ZDB-GENE-030326-4 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20240801 UniProtKB P02489 CRYAA is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:96240|PANTHER:PTN000897708|UniProtKB:O14558|UniProtKB:P02489|UniProtKB:P02511|UniProtKB:P04792|UniProtKB:Q16082|ZFIN:ZDB-GENE-030326-4 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20230604 UniProtKB P02489 CRYAA involved_in GO:0009408 response to heat biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001223|FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|FB:FBgn0001227|FB:FBgn0001229|FB:FBgn0011296|FB:FBgn0035817|FB:FBgn0035982|PANTHER:PTN000897708|UniProtKB:Q00649|WB:WBGene00002015|WB:WBGene00002016|WB:WBGene00002018|WB:WBGene00002019|WB:WBGene00004798|ZFIN:ZDB-GENE-030326-4 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20230604 UniProtKB P02489 CRYAA involved_in GO:0042026 protein refolding biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|FB:FBgn0011296|FB:FBgn0031037|FB:FBgn0035817|PANTHER:PTN000897708 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20220316 UniProtKB P02489 CRYAA enables GO:0051082 unfolded protein binding molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001223|FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|PANTHER:PTN000897708|UniProtKB:O14558|UniProtKB:P02470|UniProtKB:P02489|UniProtKB:P02511|ZFIN:ZDB-GENE-020508-1|ZFIN:ZDB-GENE-040718-419|ZFIN:ZDB-GENE-991119-2 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20220316 UniProtKB P02489 CRYAA involved_in GO:0002088 lens development in camera-type eye biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:88515|PANTHER:PTN002900910|RGD:2413|ZFIN:ZDB-GENE-020508-1 9606 Homo sapiens GO_Central Alpha-crystallin A chain 20211209 UniProtKB P02489 CRYAA enables GO:0005198 structural molecule activity molecular_function ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027476 9606 Homo sapiens UniProt Alpha-crystallin A chain 20260105 UniProtKB P02489 CRYAA enables GO:0005212 structural constituent of eye lens molecular_function ECO:0000501 IEA GO_REF:0000120 InterPro:IPR003090|UniProtKB-KW:KW-0273 9606 Homo sapiens UniProt Alpha-crystallin A chain 20260105 UniProtKB P02489 CRYAA located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Alpha-crystallin A chain 20260105 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026971|UniProtKB:P24622|ensembl:ENSMUSP00000154747|UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt Alpha-crystallin A chain 20260105 UniProtKB P02489 CRYAA involved_in GO:0007601 visual perception biological_process ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0844 9606 Homo sapiens UniProt Alpha-crystallin A chain 20260105 UniProtKB P02489 CRYAA enables GO:0046872 metal ion binding molecular_function ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0479 9606 Homo sapiens UniProt Alpha-crystallin A chain 20260105 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P07315 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P43320 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P07315 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P43320 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19651604 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22085609 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22153508 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23188086 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:O00560 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q96HA8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9H8Y8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9NZD8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:V9HW27 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25910212 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29892012 UniProtKB:Q9H8Y8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:O00560 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:Q96HA8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:Q9H8Y8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:Q9NZD8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:O00560 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q96HA8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9H8Y8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9NZD8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O15160 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O15273 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O43464 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O60333-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O60506-4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O60636 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O60830 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O75558 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O95817 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P08865 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P15976-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P19388 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P20849 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P23588 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P26998 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P35611 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P41219 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P42858 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P47804-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P48443 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P49336-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P53801 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P57682 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P60228 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P60891 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P61289 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q06547-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q0VD86 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q13322-4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q13404 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q14005-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q14533 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q14847-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q15759 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q2NKQ1-4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q3LI72 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q3SYF9 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q495U3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q496A3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q4VB01 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q5T0L3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q5VYS8-5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6DKI2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6NXG1 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6NXG1-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6NZ36-4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6P4D5-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6ZMI0-5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q7Z783 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q86SQ7-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q86WV2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8IU80-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8IUC2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8IUR5-4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8N0Y2-2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8N488 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8N6R0 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8NC06-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8TBE0 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8TDR4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8WUU4 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8WZ73-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q92615 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q92886 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q969K3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96A04 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96A09 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96BD6 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96EF9 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96GL9 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96JB6 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96KP6 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96QH2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q99683 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q99944 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9BWF3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9BXL8 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9BXU0 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9BY12-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9C004 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9H0W9-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9H4E5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9H9P5-5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NNX6-10 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NP61 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NTN9-3 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NVA1 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NWB1-5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NX94 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NXC2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NZC7-5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9P0W2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9UQB8-6 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9Y239 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9Y266 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9Y2M5 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9Y6W6 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:O95817 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9P0W2 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:19651604 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:22085609 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin A chain 20260103 UniProtKB P02489 CRYAA located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Alpha-crystallin A chain 20251115 UniProtKB P02489 CRYAA located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Alpha-crystallin A chain 20251115 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:29259299 9606 Homo sapiens UniProt Alpha-crystallin A chain 20210226 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:26004348 9606 Homo sapiens UniProt Alpha-crystallin A chain 20210218 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:19503744 9606 Homo sapiens UniProt Alpha-crystallin A chain 20201216 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:30340470 9606 Homo sapiens UniProt Alpha-crystallin A chain 20201215 UniProtKB P02489 CRYAA enables GO:0005198 structural molecule activity molecular_function ECO:0000314 IDA PMID:16303126 9606 Homo sapiens UniProt Alpha-crystallin A chain 20191121 UniProtKB P02489 CRYAA part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:16303126 9606 Homo sapiens UniProt Alpha-crystallin A chain 20191121 UniProtKB P02489 CRYAA enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:16303126 UniProtKB:P02489 9606 Homo sapiens UniProt Alpha-crystallin A chain 20191121 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12235146 UniProtKB:P00883 9606 Homo sapiens CAFA Alpha-crystallin A chain 20170113 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12235146 UniProtKB:P11415 9606 Homo sapiens CAFA Alpha-crystallin A chain 20170113 UniProtKB P02489 CRYAA involved_in GO:0050821 protein stabilization biological_process ECO:0000315 IMP PMID:12235146 9606 Homo sapiens CAFA Alpha-crystallin A chain 20170113 UniProtKB P02489 CRYAA located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:19464326 9606 Homo sapiens UniProt Alpha-crystallin A chain 20100914 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:19464326 9606 Homo sapiens UniProt Alpha-crystallin A chain 20100914 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14752512 UniProtKB:Q07812 9606 Homo sapiens UniProt Alpha-crystallin A chain 20090317 UniProtKB P02489 CRYAA NOT|involved_in GO:0042026 protein refolding biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P02470 9606 Homo sapiens UniProt Alpha-crystallin A chain 20090227 UniProtKB P02489 CRYAA enables GO:0051082 unfolded protein binding molecular_function ECO:0000353 IPI PMID:8943244 UniProtKB:P07320 9606 Homo sapiens UniProt Alpha-crystallin A chain 20090227 UniProtKB P02489 CRYAA involved_in GO:0007601 visual perception biological_process ECO:0000315 IMP PMID:9467006 9606 Homo sapiens UniProt Alpha-crystallin A chain 20090225 UniProtKB P02489 CRYAA involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000315 IMP PMID:14512969 9606 Homo sapiens UniProt Alpha-crystallin A chain 20090225 UniProtKB P02489 CRYAA enables GO:0051082 unfolded protein binding molecular_function ECO:0000315 IMP PMID:18407550 9606 Homo sapiens UniProt Alpha-crystallin A chain 20090225 UniProtKB P02489 CRYAA enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14752512 UniProtKB:Q07817 9606 Homo sapiens HGNC-UCL Alpha-crystallin A chain 20070313 UniProtKB P02489 CRYAA located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:14752512 9606 Homo sapiens HGNC-UCL Alpha-crystallin A chain 20070313 UniProtKB P02489 CRYAA involved_in GO:0032387 negative regulation of intracellular transport biological_process ECO:0000314 IDA PMID:14752512 9606 Homo sapiens HGNC-UCL Alpha-crystallin A chain 20070313 UniProtKB P02489 CRYAA involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000314 IDA PMID:14752512 9606 Homo sapiens HGNC-UCL Alpha-crystallin A chain 20070313 UniProtKB P02489 CRYAA involved_in GO:0007601 visual perception biological_process ECO:0000315 IMP PMID:14512969 9606 Homo sapiens UniProt Alpha-crystallin A chain 20040806