GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB P02511 CRYAB involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:88515|MGI:MGI:88516|MGI:MGI:96240|PANTHER:PTN002264124|RGD:2414|RGD:621554|UniProtKB:P02489|UniProtKB:P02511 9606 Homo sapiens GO_Central Alpha-crystallin B chain 20241121 UniProtKB P02511 CRYAB is_active_in GO:0005737 cytoplasm cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001223|FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|FB:FBgn0011296|FB:FBgn0031037|MGI:MGI:88515|MGI:MGI:88516|MGI:MGI:96240|PANTHER:PTN000897708|RGD:2414|RGD:61306|UniProtKB:O14558|UniProtKB:P02470|UniProtKB:P02489|UniProtKB:P02511|UniProtKB:P04792|UniProtKB:Q00649|UniProtKB:Q16082|WB:WBGene00002011|WB:WBGene00002013|WB:WBGene00002015|WB:WBGene00002016|WB:WBGene00002023|WB:WBGene00004798|ZFIN:ZDB-GENE-030326-4 9606 Homo sapiens GO_Central Alpha-crystallin B chain 20240801 UniProtKB P02511 CRYAB is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:96240|PANTHER:PTN000897708|UniProtKB:O14558|UniProtKB:P02489|UniProtKB:P02511|UniProtKB:P04792|UniProtKB:Q16082|ZFIN:ZDB-GENE-030326-4 9606 Homo sapiens GO_Central Alpha-crystallin B chain 20230604 UniProtKB P02511 CRYAB involved_in GO:0009408 response to heat biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001223|FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|FB:FBgn0001227|FB:FBgn0001229|FB:FBgn0011296|FB:FBgn0035817|FB:FBgn0035982|PANTHER:PTN000897708|UniProtKB:Q00649|WB:WBGene00002015|WB:WBGene00002016|WB:WBGene00002018|WB:WBGene00002019|WB:WBGene00004798|ZFIN:ZDB-GENE-030326-4 9606 Homo sapiens GO_Central Alpha-crystallin B chain 20230604 UniProtKB P02511 CRYAB involved_in GO:0042026 protein refolding biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|FB:FBgn0011296|FB:FBgn0031037|FB:FBgn0035817|PANTHER:PTN000897708 9606 Homo sapiens GO_Central Alpha-crystallin B chain 20220316 UniProtKB P02511 CRYAB enables GO:0051082 unfolded protein binding molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0001223|FB:FBgn0001224|FB:FBgn0001225|FB:FBgn0001226|PANTHER:PTN000897708|UniProtKB:O14558|UniProtKB:P02470|UniProtKB:P02489|UniProtKB:P02511|ZFIN:ZDB-GENE-020508-1|ZFIN:ZDB-GENE-040718-419|ZFIN:ZDB-GENE-991119-2 9606 Homo sapiens GO_Central Alpha-crystallin B chain 20220316 UniProtKB P02511 CRYAB enables GO:0005198 structural molecule activity molecular_function ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027476 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB enables GO:0005212 structural constituent of eye lens molecular_function ECO:0000501 IEA GO_REF:0000120 InterPro:IPR003090|UniProtKB-KW:KW-0273 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB located_in GO:0005576 extracellular region cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0243 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB located_in GO:0005737 cytoplasm cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026971|UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB located_in GO:0005764 lysosome cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0158 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB involved_in GO:0009892 negative regulation of metabolic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00028100 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB enables GO:0046872 metal ion binding molecular_function ECO:0007322 IEA GO_REF:0000043 UniProtKB-KW:KW-0479 9606 Homo sapiens UniProt Alpha-crystallin B chain 20260105 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P07315 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11700327 UniProtKB:P43320 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P07315 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P43320 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16049941 UniProtKB:P05067 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17046756 UniProtKB:P05813 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18330356 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19651604 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22085609 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22153508 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22158051 UniProtKB:P35222 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23188086 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23188086 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23188086 UniProtKB:Q16082 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23542032 UniProtKB:Q3UBX0 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24183572 UniProtKB:P22914 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25910212 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26465331 UniProtKB:Q16082 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P02489 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q3LI64 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9H8Y8 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O00471 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P05067 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P09525 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P35222 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P60891 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q14194 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6QEF8-4 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q6UY14-3 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8WUY3 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96LI6-3 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:P04792 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:12601044 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:18330356 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:19651604 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:20802487 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:21464278 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:22143763 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:22153508 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:23188086 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:24183572 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:26465331 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:27226619 UniProtKB:P02511 9606 Homo sapiens IntAct Alpha-crystallin B chain 20260103 UniProtKB P02511 CRYAB located_in GO:0005739 mitochondrion cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23927|ensembl:ENSMUSP00000149803 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0005829 cytosol cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23927|ensembl:ENSMUSP00000149803 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0005886 plasma membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23927|ensembl:ENSMUSP00000149803 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0006457 protein folding biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB enables GO:0008017 microtubule binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB enables GO:0008092 cytoskeletal protein binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0009986 cell surface cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0030018 Z disc cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23927|ensembl:ENSMUSP00000149803 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0030308 negative regulation of cell growth biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0030424 axon cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0031109 microtubule polymerization or depolymerization biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0031430 M band cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0031674 I band cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0032355 response to estradiol biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0032432 actin filament bundle cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0042542 response to hydrogen peroxide biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00027746|UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens UniProt Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0043197 dendritic spine cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0043204 perikaryon cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0043292 contractile muscle fiber cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23927|ensembl:ENSMUSP00000149803 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:0051403 stress-activated MAPK cascade biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0097060 synaptic membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0097512 cardiac myofibril cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB involved_in GO:2000378 negative regulation of reactive oxygen species metabolic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P23928|ensembl:ENSRNOP00000055901 9606 Homo sapiens Ensembl Alpha-crystallin B chain 20251226 UniProtKB P02511 CRYAB located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Alpha-crystallin B chain 20251115 UniProtKB P02511 CRYAB located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Alpha-crystallin B chain 20251115 UniProtKB P02511 CRYAB acts_upstream_of_or_within GO:0043067 regulation of programmed cell death biological_process ECO:0000315 IMP PMID:23542032 9606 Homo sapiens MGI Alpha-crystallin B chain 20230206 UniProtKB P02511 CRYAB enables GO:0005198 structural molecule activity molecular_function ECO:0000314 IDA PMID:16303126 9606 Homo sapiens UniProt Alpha-crystallin B chain 20191121 UniProtKB P02511 CRYAB part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:16303126 9606 Homo sapiens UniProt Alpha-crystallin B chain 20191121 UniProtKB P02511 CRYAB enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:16303126 UniProtKB:P02511 9606 Homo sapiens UniProt Alpha-crystallin B chain 20191121 UniProtKB P02511 CRYAB involved_in GO:0031333 negative regulation of protein-containing complex assembly biological_process ECO:0000314 IDA PMID:23106396 9606 Homo sapiens ARUK-UCL Alpha-crystallin B chain 20190717 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20587334 UniProtKB:Q53QV2 9606 Homo sapiens UniProt Alpha-crystallin B chain 20190129 UniProtKB P02511 CRYAB located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:20587334 9606 Homo sapiens UniProt Alpha-crystallin B chain 20190129 UniProtKB P02511 CRYAB located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:20587334 9606 Homo sapiens UniProt Alpha-crystallin B chain 20190129 UniProtKB P02511 CRYAB part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:20587334 9606 Homo sapiens UniProt Alpha-crystallin B chain 20190129 UniProtKB P02511 CRYAB involved_in GO:0045892 negative regulation of DNA-templated transcription biological_process ECO:0000314 IDA PMID:20587334 9606 Homo sapiens UniProt Alpha-crystallin B chain 20190129 UniProtKB P02511 CRYAB enables GO:0001540 amyloid-beta binding molecular_function ECO:0000353 IPI PMID:23106396 UniProtKB:P05067-PRO_0000000093 9606 Homo sapiens ARUK-UCL Alpha-crystallin B chain 20180118 UniProtKB P02511 CRYAB enables GO:0044877 protein-containing complex binding molecular_function ECO:0000353 IPI PMID:23106396 ComplexPortal:CPX-1180 9606 Homo sapiens ARUK-UCL Alpha-crystallin B chain 20180118 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28470624 UniProtKB:P17661 9606 Homo sapiens UniProt Alpha-crystallin B chain 20170810 UniProtKB P02511 CRYAB involved_in GO:1905907 negative regulation of amyloid fibril formation biological_process ECO:0000314 IDA PMID:23106396 9606 Homo sapiens ARUK-UCL Alpha-crystallin B chain 20170203 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12235146 UniProtKB:P00883 9606 Homo sapiens CAFA Alpha-crystallin B chain 20170113 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12235146 UniProtKB:P11415 9606 Homo sapiens CAFA Alpha-crystallin B chain 20170113 UniProtKB P02511 CRYAB involved_in GO:0050821 protein stabilization biological_process ECO:0000315 IMP PMID:12235146 9606 Homo sapiens CAFA Alpha-crystallin B chain 20170113 UniProtKB P02511 CRYAB located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5082356 9606 Homo sapiens Reactome Alpha-crystallin B chain 20151022 UniProtKB P02511 CRYAB located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:23533145 9606 Homo sapiens UniProt Alpha-crystallin B chain 20140714 UniProtKB P02511 CRYAB located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19056867 9606 Homo sapiens UniProt Alpha-crystallin B chain 20131024 UniProtKB P02511 CRYAB acts_upstream_of_or_within GO:0071480 cellular response to gamma radiation biological_process ECO:0000315 IMP PMID:23542032 9606 Homo sapiens MGI Alpha-crystallin B chain 20130620 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14752512 UniProtKB:Q07812 9606 Homo sapiens UniProt Alpha-crystallin B chain 20120708 UniProtKB P02511 CRYAB located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:19464326 9606 Homo sapiens UniProt Alpha-crystallin B chain 20100914 UniProtKB P02511 CRYAB located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:19464326 9606 Homo sapiens UniProt Alpha-crystallin B chain 20100914 UniProtKB P02511 CRYAB located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA GO_REF:0000054 9606 Homo sapiens LIFEdb Alpha-crystallin B chain 20100607 UniProtKB P02511 CRYAB enables GO:0042803 protein homodimerization activity molecular_function ECO:0000353 IPI PMID:19646995 UniProtKB:P02511 9606 Homo sapiens UniProt Alpha-crystallin B chain 20091006 UniProtKB P02511 CRYAB enables GO:0051082 unfolded protein binding molecular_function ECO:0000353 IPI PMID:16303126 UniProtKB:P07315 9606 Homo sapiens UniProt Alpha-crystallin B chain 20090227 UniProtKB P02511 CRYAB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14752512 UniProtKB:Q07817 9606 Homo sapiens HGNC-UCL Alpha-crystallin B chain 20070313 UniProtKB P02511 CRYAB located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:14752512 9606 Homo sapiens HGNC-UCL Alpha-crystallin B chain 20070313 UniProtKB P02511 CRYAB involved_in GO:0032387 negative regulation of intracellular transport biological_process ECO:0000314 IDA PMID:14752512 9606 Homo sapiens HGNC-UCL Alpha-crystallin B chain 20070313 UniProtKB P02511 CRYAB involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000314 IDA PMID:14752512 9606 Homo sapiens HGNC-UCL Alpha-crystallin B chain 20070313 UniProtKB P02511 CRYAB involved_in GO:0006457 protein folding biological_process ECO:0000303 NAS PMID:9731540 9606 Homo sapiens PINC Alpha-crystallin B chain 20040811 UniProtKB P02511 CRYAB involved_in GO:0006936 muscle contraction biological_process ECO:0000304 TAS PMID:9731540 9606 Homo sapiens PINC Alpha-crystallin B chain 20030904