GENE PRODUCT DB	GENE PRODUCT ID	SYMBOL	QUALIFIER	GO TERM	GO NAME	GO ASPECT	ECO ID	GO EVIDENCE CODE	REFERENCE	WITH/FROM	TAXON ID	TAXON NAME	ASSIGNED BY	GENE NAME	DATE
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	molecular_function	ECO:0000318	IBA	GO_REF:0000033	MGI:MGI:2386848|PANTHER:PTN008705817|UniProtKB:Q7L1T6	9606	Homo sapiens	GO_Central	Cytochrome b5 reductase 4	20240104
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0020037	heme binding	molecular_function	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN008705817|RGD:621834	9606	Homo sapiens	GO_Central	Cytochrome b5 reductase 4	20240104
UniProtKB	Q7L1T6	CYB5R4	is_active_in	GO:0005783	endoplasmic reticulum	cellular_component	ECO:0000318	IBA	GO_REF:0000033	MGI:MGI:2386848|PANTHER:PTN000452141|UniProtKB:Q7L1T6	9606	Homo sapiens	GO_Central	Cytochrome b5 reductase 4	20170228
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0006801	superoxide metabolic process	biological_process	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN000452141|UniProtKB:Q7L1T6	9606	Homo sapiens	GO_Central	Cytochrome b5 reductase 4	20170228
UniProtKB	Q7L1T6	CYB5R4	located_in	GO:0005783	endoplasmic reticulum	cellular_component	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:Q3TDX8|ensembl:ENSMUSP00000126119|UniProtKB-SubCell:SL-0095	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20260601
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0016491	oxidoreductase activity	molecular_function	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR001433|InterPro:IPR017927	9606	Homo sapiens	InterPro	Cytochrome b5 reductase 4	20260601
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	molecular_function	ECO:0000256	IEA	GO_REF:0000117	ARBA:ARBA00027025	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20260601
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0020037	heme binding	molecular_function	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR018506	9606	Homo sapiens	InterPro	Cytochrome b5 reductase 4	20260601
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0090524	cytochrome-b5 reductase activity, acting on NADH	molecular_function	ECO:0000501	IEA	GO_REF:0000120	RHEA:46680|EC:1.6.2.2	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20260601
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	molecular_function	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q3TDX8|ensembl:ENSMUSP00000126119	9606	Homo sapiens	Ensembl	Cytochrome b5 reductase 4	20260529
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0015701	bicarbonate transport	biological_process	ECO:0000304	TAS	Reactome:R-HSA-1237044		9606	Homo sapiens	Reactome	Cytochrome b5 reductase 4	20260316
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	molecular_function	ECO:0000304	TAS	Reactome:R-HSA-6806831		9606	Homo sapiens	Reactome	Cytochrome b5 reductase 4	20250815
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0072593	reactive oxygen species metabolic process	biological_process	ECO:0000314	IDA	PMID:15131110		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20210122
UniProtKB	Q7L1T6	CYB5R4	located_in	GO:0005789	endoplasmic reticulum membrane	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-6806831		9606	Homo sapiens	Reactome	Cytochrome b5 reductase 4	20151027
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0030073	insulin secretion	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q3TDX8	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080911
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0042593	glucose homeostasis	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q3TDX8	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080911
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0046677	response to antibiotic	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q3TDX8	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080911
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0048468	cell development	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q3TDX8	9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080911
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0003032	detection of oxygen	biological_process	ECO:0000303	NAS	PMID:10611283		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	molecular_function	ECO:0000314	IDA	PMID:10611283		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	located_in	GO:0005783	endoplasmic reticulum	cellular_component	ECO:0000314	IDA	PMID:15131110		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	involved_in	GO:0006801	superoxide metabolic process	biological_process	ECO:0000314	IDA	PMID:10611283		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	NOT|enables	GO:0016174	NAD(P)H oxidase H2O2-forming activity	molecular_function	ECO:0000314	IDA	PMID:15131110		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0016174	NAD(P)H oxidase H2O2-forming activity	molecular_function	ECO:0000314	IDA	PMID:10611283		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	enables	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	molecular_function	ECO:0000314	IDA	PMID:15131110		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
UniProtKB	Q7L1T6	CYB5R4	located_in	GO:0048471	perinuclear region of cytoplasm	cellular_component	ECO:0000314	IDA	PMID:10611283		9606	Homo sapiens	UniProt	Cytochrome b5 reductase 4	20080507
