GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q96HY6 DDRGK1 enables GO:0044389 ubiquitin-like protein ligase binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008298954|UniProtKB:Q96HY6 9606 Homo sapiens GO_Central DDRGK domain-containing protein 1 20230720 UniProtKB Q96HY6 DDRGK1 involved_in GO:0051216 cartilage development biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1924256|PANTHER:PTN008298962|UniProtKB:Q96HY6|ZFIN:ZDB-GENE-040426-1050 9606 Homo sapiens GO_Central DDRGK domain-containing protein 1 20230720 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903895 negative regulation of IRE1-mediated unfolded protein response biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1924256|PANTHER:PTN008298962|UniProtKB:Q96HY6 9606 Homo sapiens GO_Central DDRGK domain-containing protein 1 20230720 UniProtKB Q96HY6 DDRGK1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0097 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20260601 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:O94874 9606 Homo sapiens IntAct DDRGK domain-containing protein 1 20260530 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35156780 UniProtKB:P13569 9606 Homo sapiens IntAct DDRGK domain-containing protein 1 20260530 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36012204 UniProtKB:P13569 9606 Homo sapiens IntAct DDRGK domain-containing protein 1 20260530 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:37595036 UniProtKB:O94874 9606 Homo sapiens IntAct DDRGK domain-containing protein 1 20260530 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:O94874 9606 Homo sapiens IntAct DDRGK domain-containing protein 1 20260530 UniProtKB Q96HY6 DDRGK1 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens Ensembl DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:0034976 response to endoplasmic reticulum stress biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens Ensembl DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:D3ZAS9|ensembl:ENSRNOP00000036810 9606 Homo sapiens Ensembl DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:0051216 cartilage development biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00089273|UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:1900100 positive regulation of plasma cell differentiation biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens Ensembl DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903895 negative regulation of IRE1-mediated unfolded protein response biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00092208|UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903898 negative regulation of PERK-mediated unfolded protein response biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens Ensembl DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 involved_in GO:1905552 positive regulation of protein localization to endoplasmic reticulum biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q80WW9|ensembl:ENSMUSP00000086988 9606 Homo sapiens Ensembl DDRGK domain-containing protein 1 20260529 UniProtKB Q96HY6 DDRGK1 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA DDRGK domain-containing protein 1 20251115 UniProtKB Q96HY6 DDRGK1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000269 EXP PMID:20018847 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20251027 UniProtKB Q96HY6 DDRGK1 involved_in GO:0043123 positive regulation of canonical NF-kappaB signal transduction biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20241220 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:36121123 9606 Homo sapiens ComplexPortal DDRGK domain-containing protein 1 20240903 UniProtKB Q96HY6 DDRGK1 part_of GO:1990234 transferase complex cellular_component ECO:0000353 IPI PMID:36121123 9606 Homo sapiens ComplexPortal DDRGK domain-containing protein 1 20240903 UniProtKB Q96HY6 DDRGK1 enables GO:0141185 UFM1-modified protein reader activity molecular_function ECO:0000314 IDA PMID:36121123 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240326 UniProtKB Q96HY6 DDRGK1 enables GO:0141185 UFM1-modified protein reader activity molecular_function ECO:0000314 IDA PMID:36543799 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240326 UniProtKB Q96HY6 DDRGK1 enables GO:0141185 UFM1-modified protein reader activity molecular_function ECO:0000314 IDA PMID:37595036 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240326 UniProtKB Q96HY6 DDRGK1 enables GO:0141185 UFM1-modified protein reader activity molecular_function ECO:0000314 IDA PMID:38383785 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240326 UniProtKB Q96HY6 DDRGK1 enables GO:0141185 UFM1-modified protein reader activity molecular_function ECO:0000314 IDA PMID:38383789 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240326 UniProtKB Q96HY6 DDRGK1 involved_in GO:1900100 positive regulation of plasma cell differentiation biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q80WW9 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240325 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903898 negative regulation of PERK-mediated unfolded protein response biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q80WW9 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240325 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:35753586 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240322 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:37795761 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240322 UniProtKB Q96HY6 DDRGK1 is_active_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:36543799 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 involved_in GO:0045732 positive regulation of protein catabolic process biological_process ECO:0000314 IDA PMID:36543799 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 involved_in GO:0045732 positive regulation of protein catabolic process biological_process ECO:0000314 IDA PMID:36543799 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:36543799 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:37595036 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:37595036 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 involved_in GO:0140501 positive regulation of reticulophagy biological_process ECO:0000314 IDA PMID:36543799 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240320 UniProtKB Q96HY6 DDRGK1 is_active_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:38383785 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 is_active_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:38383789 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0032790 ribosome disassembly biological_process ECO:0000314 IDA PMID:38383785 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0032790 ribosome disassembly biological_process ECO:0000314 IDA PMID:38383789 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000315 IMP PMID:30626644 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:36121123 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:38383785 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:38383789 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:38383785 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:38383789 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20240319 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28128204 UniProtKB:O75460 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32160526 UniProtKB:O94874 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:32160526 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:0031647 regulation of protein stability biological_process ECO:0000314 IDA PMID:28128204 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:0034976 response to endoplasmic reticulum stress biological_process ECO:0000314 IDA PMID:28128204 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:0034976 response to endoplasmic reticulum stress biological_process ECO:0000314 IDA PMID:32160526 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:0061709 reticulophagy biological_process ECO:0000314 IDA PMID:32160526 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:0070972 protein localization to endoplasmic reticulum biological_process ECO:0000314 IDA PMID:32160526 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:0071569 protein ufmylation biological_process ECO:0000314 IDA PMID:32160526 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903895 negative regulation of IRE1-mediated unfolded protein response biological_process ECO:0000314 IDA PMID:28128204 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903895 negative regulation of IRE1-mediated unfolded protein response biological_process ECO:0000314 IDA PMID:32160526 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20200526 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28263186 UniProtKB:P48436 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20180621 UniProtKB Q96HY6 DDRGK1 involved_in GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:28263186 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20180621 UniProtKB Q96HY6 DDRGK1 involved_in GO:0051216 cartilage development biological_process ECO:0000315 IMP PMID:28263186 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20180621 UniProtKB Q96HY6 DDRGK1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161124 UniProtKB Q96HY6 DDRGK1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161124 UniProtKB Q96HY6 DDRGK1 involved_in GO:1902808 positive regulation of cell cycle G1/S phase transition biological_process ECO:0000305 IC PMID:23675531 GO:0008284|GO:0045944 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161124 UniProtKB Q96HY6 DDRGK1 involved_in GO:0030335 positive regulation of cell migration biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161123 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23675531 UniProtKB:P25963 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 located_in GO:0005737 cytoplasm cellular_component ECO:0000304 TAS PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:0008284 positive regulation of cell population proliferation biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:0010628 positive regulation of gene expression biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:0010628 positive regulation of gene expression biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:0010629 negative regulation of gene expression biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:D3ZAS9 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:1905552 positive regulation of protein localization to endoplasmic reticulum biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q80WW9 9606 Homo sapiens ParkinsonsUK-UCL DDRGK domain-containing protein 1 20161103 UniProtKB Q96HY6 DDRGK1 involved_in GO:1990592 protein K69-linked ufmylation biological_process ECO:0000314 IDA PMID:25219498 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20150415 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20228063 UniProtKB:Q96JB5 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20150226 UniProtKB Q96HY6 DDRGK1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:20228063 9606 Homo sapiens MGI DDRGK domain-containing protein 1 20141215 UniProtKB Q96HY6 DDRGK1 involved_in GO:0033146 regulation of intracellular estrogen receptor signaling pathway biological_process ECO:0000314 IDA PMID:25219498 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20141211 UniProtKB Q96HY6 DDRGK1 involved_in GO:0034976 response to endoplasmic reticulum stress biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q80WW9 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20141210 UniProtKB Q96HY6 DDRGK1 involved_in GO:1901800 positive regulation of proteasomal protein catabolic process biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20141208 UniProtKB Q96HY6 DDRGK1 involved_in GO:1903721 positive regulation of I-kappaB phosphorylation biological_process ECO:0000315 IMP PMID:23675531 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20141208 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:Q15650 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20141119 UniProtKB Q96HY6 DDRGK1 enables GO:0044389 ubiquitin-like protein ligase binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:O94874 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20141119 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20018847 UniProtKB:O94874 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20100204 UniProtKB Q96HY6 DDRGK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20018847 UniProtKB:Q9Y3C8 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20100204 UniProtKB Q96HY6 DDRGK1 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:20018847 9606 Homo sapiens UniProt DDRGK domain-containing protein 1 20100204