GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q8IXB1 DNAJC10 is_active_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002546877|UniProtKB:Q8IXB1|WB:WBGene00001045 9606 Homo sapiens GO_Central Endoplasmic reticulum disulfide reductase DNAJC10 20211118 UniProtKB Q8IXB1 DNAJC10 enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1914111|PANTHER:PTN002546877|UniProtKB:Q8IXB1 9606 Homo sapiens GO_Central Endoplasmic reticulum disulfide reductase DNAJC10 20211118 UniProtKB Q8IXB1 DNAJC10 enables GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor molecular_function ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1914111|PANTHER:PTN002546877 9606 Homo sapiens GO_Central Endoplasmic reticulum disulfide reductase DNAJC10 20211118 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0036498 IRE1-mediated unfolded protein response biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002546877|WB:WBGene00001045 9606 Homo sapiens GO_Central Endoplasmic reticulum disulfide reductase DNAJC10 20211118 UniProtKB Q8IXB1 DNAJC10 enables GO:0051787 misfolded protein binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002546877|UniProtKB:Q8IXB1 9606 Homo sapiens GO_Central Endoplasmic reticulum disulfide reductase DNAJC10 20211118 UniProtKB Q8IXB1 DNAJC10 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00028672|UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392|InterPro:IPR021170 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260601 UniProtKB Q8IXB1 DNAJC10 located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0096 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260601 UniProtKB Q8IXB1 DNAJC10 enables GO:0015036 disulfide oxidoreductase activity molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392|InterPro:IPR021170 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260601 UniProtKB Q8IXB1 DNAJC10 enables GO:0019153 protein-disulfide reductase (glutathione) activity molecular_function ECO:0000501 IEA GO_REF:0000120 RHEA:21064|EC:1.8.4.2 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260601 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0034975 protein folding in endoplasmic reticulum biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR021170 9606 Homo sapiens InterPro Endoplasmic reticulum disulfide reductase DNAJC10 20260601 UniProtKB Q8IXB1 DNAJC10 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19706418 UniProtKB:Q8IWF2 9606 Homo sapiens IntAct Endoplasmic reticulum disulfide reductase DNAJC10 20260530 UniProtKB Q8IXB1 DNAJC10 enables GO:0001671 ATPase activator activity molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392 9606 Homo sapiens Ensembl Endoplasmic reticulum disulfide reductase DNAJC10 20260529 UniProtKB Q8IXB1 DNAJC10 enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026550|UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260529 UniProtKB Q8IXB1 DNAJC10 enables GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392 9606 Homo sapiens Ensembl Endoplasmic reticulum disulfide reductase DNAJC10 20260529 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0036503 ERAD pathway biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00029018|UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260529 UniProtKB Q8IXB1 DNAJC10 enables GO:0051087 protein-folding chaperone binding molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00088077|UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260529 UniProtKB Q8IXB1 DNAJC10 enables GO:0051117 ATPase binding molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00087746|UniProtKB:Q9DC23|ensembl:ENSMUSP00000028392 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20260529 UniProtKB Q8IXB1 DNAJC10 located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000269 EXP PMID:12411443 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20251027 UniProtKB Q8IXB1 DNAJC10 located_in GO:0016020 membrane cellular_component ECO:0007005 HDA PMID:19946888 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20140627 UniProtKB Q8IXB1 DNAJC10 located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000314 IDA PMID:23769672 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20130716 UniProtKB Q8IXB1 DNAJC10 enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000314 IDA PMID:23769672 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20130716 UniProtKB Q8IXB1 DNAJC10 enables GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor molecular_function ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9DC23 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20130716 UniProtKB Q8IXB1 DNAJC10 enables GO:0030544 Hsp70 protein binding molecular_function ECO:0000353 IPI PMID:23769672 UniProtKB:P11021 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20130716 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0034975 protein folding in endoplasmic reticulum biological_process ECO:0000314 IDA PMID:23769672 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20130716 UniProtKB Q8IXB1 DNAJC10 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:12411443 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110131 UniProtKB Q8IXB1 DNAJC10 enables GO:0015036 disulfide oxidoreductase activity molecular_function ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9DC23 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110131 UniProtKB Q8IXB1 DNAJC10 part_of GO:0034663 endoplasmic reticulum chaperone complex cellular_component ECO:0000314 IDA PMID:18400946 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110131 UniProtKB Q8IXB1 DNAJC10 enables GO:0051087 protein-folding chaperone binding molecular_function ECO:0000314 IDA PMID:12411443 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110131 UniProtKB Q8IXB1 DNAJC10 enables GO:0051117 ATPase binding molecular_function ECO:0000353 IPI PMID:12411443 UniProtKB:P11021 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110131 UniProtKB Q8IXB1 DNAJC10 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19706418 UniProtKB:Q8IWF2 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110128 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0034976 response to endoplasmic reticulum stress biological_process ECO:0000314 IDA PMID:19122239 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110128 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0036503 ERAD pathway biological_process ECO:0000315 IMP PMID:18400946 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110128 UniProtKB Q8IXB1 DNAJC10 enables GO:0051787 misfolded protein binding molecular_function ECO:0000314 IDA PMID:18400946 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110128 UniProtKB Q8IXB1 DNAJC10 involved_in GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress biological_process ECO:0000314 IDA PMID:19122239 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20110128 UniProtKB Q8IXB1 DNAJC10 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19815549 UniProtKB:Q5HYA8 9606 Homo sapiens UniProt Endoplasmic reticulum disulfide reductase DNAJC10 20100203