GENE PRODUCT DB	GENE PRODUCT ID	SYMBOL	QUALIFIER	GO TERM	GO NAME	GO ASPECT	ECO ID	GO EVIDENCE CODE	REFERENCE	WITH/FROM	TAXON ID	TAXON NAME	ASSIGNED BY	GENE NAME	DATE
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0030968	endoplasmic reticulum unfolded protein response	biological_process	ECO:0000318	IBA	GO_REF:0000033	FB:FBgn0023511|FB:FBgn0032480|PANTHER:PTN002271980	9606	Homo sapiens	GO_Central	ER degradation-enhancing alpha-mannosidase-like protein 2	20240418
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway	biological_process	ECO:0000318	IBA	GO_REF:0000033	FB:FBgn0023511|FB:FBgn0032480|PANTHER:PTN002271980	9606	Homo sapiens	GO_Central	ER degradation-enhancing alpha-mannosidase-like protein 2	20240418
UniProtKB	Q9BV94	EDEM2	enables	GO:0005509	calcium ion binding	molecular_function	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR001382|InterPro:IPR036026	9606	Homo sapiens	InterPro	ER degradation-enhancing alpha-mannosidase-like protein 2	20260601
UniProtKB	Q9BV94	EDEM2	located_in	GO:0005788	endoplasmic reticulum lumen	cellular_component	ECO:0007322	IEA	GO_REF:0000044	UniProtKB-SubCell:SL-0096	9606	Homo sapiens	UniProt	ER degradation-enhancing alpha-mannosidase-like protein 2	20260601
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0005975	carbohydrate metabolic process	biological_process	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR012341	9606	Homo sapiens	InterPro	ER degradation-enhancing alpha-mannosidase-like protein 2	20260601
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0009100	glycoprotein metabolic process	biological_process	ECO:0000256	IEA	GO_REF:0000117	ARBA:ARBA00027558	9606	Homo sapiens	UniProt	ER degradation-enhancing alpha-mannosidase-like protein 2	20260601
UniProtKB	Q9BV94	EDEM2	located_in	GO:0016020	membrane	cellular_component	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR001382|InterPro:IPR036026	9606	Homo sapiens	InterPro	ER degradation-enhancing alpha-mannosidase-like protein 2	20260601
UniProtKB	Q9BV94	EDEM2	involved_in	GO:1904380	endoplasmic reticulum mannose trimming	biological_process	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR044674	9606	Homo sapiens	InterPro	ER degradation-enhancing alpha-mannosidase-like protein 2	20260601
UniProtKB	Q9BV94	EDEM2	involved_in	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol	biological_process	ECO:0000501	IEA	GO_REF:0000120	ARBA:ARBA00087563|UniProtKB:Q8BJT9|ensembl:ENSMUSP00000041202	9606	Homo sapiens	UniProt	ER degradation-enhancing alpha-mannosidase-like protein 2	20260529
UniProtKB	Q9BV94	EDEM2	enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000304	TAS	Reactome:R-HSA-901024		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20260222
UniProtKB	Q9BV94	EDEM2	enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000304	TAS	Reactome:R-HSA-901036		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20260222
UniProtKB	Q9BV94	EDEM2	enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000304	TAS	Reactome:R-HSA-901039		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20260222
UniProtKB	Q9BV94	EDEM2	enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000304	TAS	Reactome:R-HSA-901074		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20260222
UniProtKB	Q9BV94	EDEM2	enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000304	TAS	Reactome:R-HSA-9696807		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20260222
UniProtKB	Q9BV94	EDEM2	involved_in	GO:1904380	endoplasmic reticulum mannose trimming	biological_process	ECO:0000315	IMP	PMID:25092655		9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20250604
UniProtKB	Q9BV94	EDEM2	involved_in	GO:1904380	endoplasmic reticulum mannose trimming	biological_process	ECO:0000304	TAS	Reactome:R-HSA-901032		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20241113
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0036503	ERAD pathway	biological_process	ECO:0000315	IMP	PMID:15537790		9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20231121
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0036503	ERAD pathway	biological_process	ECO:0000315	IMP	PMID:25092655		9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20231121
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0019082	viral protein processing	biological_process	ECO:0000304	TAS	Reactome:R-HSA-9694548		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20230308
UniProtKB	Q9BV94	EDEM2	involved_in	GO:0036510	trimming of terminal mannose on C branch	biological_process	ECO:0000304	TAS	Reactome:R-HSA-901039		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20230308
UniProtKB	Q9BV94	EDEM2	located_in	GO:0005788	endoplasmic reticulum lumen	cellular_component	ECO:0000269	EXP	PMID:15537790		9606	Homo sapiens	UniProt	ER degradation-enhancing alpha-mannosidase-like protein 2	20180613
UniProtKB	Q9BV94	EDEM2	located_in	GO:0005783	endoplasmic reticulum	cellular_component	ECO:0000314	IDA	PMID:24200403		9606	Homo sapiens	MGI	ER degradation-enhancing alpha-mannosidase-like protein 2	20180205
UniProtKB	Q9BV94	EDEM2	involved_in	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol	biological_process	ECO:0000315	IMP	PMID:24200403		9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20150609
UniProtKB	Q9BV94	EDEM2	involved_in	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol	biological_process	ECO:0000316	IGI	PMID:24200403	UniProtKB:Q92611	9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20150609
UniProtKB	Q9BV94	EDEM2	located_in	GO:0044322	endoplasmic reticulum quality control compartment	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-901024		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20150608
UniProtKB	Q9BV94	EDEM2	located_in	GO:0044322	endoplasmic reticulum quality control compartment	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-901036		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20150608
UniProtKB	Q9BV94	EDEM2	located_in	GO:0044322	endoplasmic reticulum quality control compartment	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-901039		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20150608
UniProtKB	Q9BV94	EDEM2	located_in	GO:0044322	endoplasmic reticulum quality control compartment	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-901074		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20150608
UniProtKB	Q9BV94	EDEM2	located_in	GO:0044322	endoplasmic reticulum quality control compartment	cellular_component	ECO:0000304	TAS	Reactome:R-HSA-9696807		9606	Homo sapiens	Reactome	ER degradation-enhancing alpha-mannosidase-like protein 2	20150608
UniProtKB	Q9BV94	EDEM2	enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000315	IMP	PMID:25092655		9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20150602
UniProtKB	Q9BV94	EDEM2	located_in	GO:0005783	endoplasmic reticulum	cellular_component	ECO:0000314	IDA	PMID:15537790		9606	Homo sapiens	ParkinsonsUK-UCL	ER degradation-enhancing alpha-mannosidase-like protein 2	20150602
UniProtKB	Q9BV94	EDEM2	NOT|enables	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	molecular_function	ECO:0000314	IDA	PMID:15537790		9606	Homo sapiens	UniProt	ER degradation-enhancing alpha-mannosidase-like protein 2	20110412