GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB O00418 EEF2K is_active_in GO:0014069 postsynaptic density cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN001021493|RGD:2538 9606 Homo sapiens GO_Central Eukaryotic elongation factor 2 kinase 20250603 UniProtKB O00418 EEF2K involved_in GO:0140245 regulation of translation at postsynapse biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN001021493|RGD:2538 9606 Homo sapiens GO_Central Eukaryotic elongation factor 2 kinase 20250603 UniProtKB O00418 EEF2K enables GO:0004686 elongation factor-2 kinase activity molecular_function ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1195261|PANTHER:PTN001021493|RGD:2538|UniProtKB:O00418|WB:WBGene00001160 9606 Homo sapiens GO_Central Eukaryotic elongation factor 2 kinase 20220311 UniProtKB O00418 EEF2K enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR004166 9606 Homo sapiens InterPro Eukaryotic elongation factor 2 kinase 20260601 UniProtKB O00418 EEF2K enables GO:0004686 elongation factor-2 kinase activity molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00087881|UniProtKB:O08796|ensembl:ENSMUSP00000046595|UniProtKB:P70531|ensembl:ENSRNOP00000022726|InterPro:IPR017400|InterPro:IPR047588|RHEA:21436|EC:2.7.11.20 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20260601 UniProtKB O00418 EEF2K enables GO:0005509 calcium ion binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR017400 9606 Homo sapiens InterPro Eukaryotic elongation factor 2 kinase 20260601 UniProtKB O00418 EEF2K enables GO:0005516 calmodulin binding molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:O08796|ensembl:ENSMUSP00000046595|InterPro:IPR017400 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20260601 UniProtKB O00418 EEF2K enables GO:0005524 ATP binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR004166 9606 Homo sapiens InterPro Eukaryotic elongation factor 2 kinase 20260601 UniProtKB O00418 EEF2K involved_in GO:0002931 response to ischemia biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K is_active_in GO:0014069 postsynaptic density cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0032869 cellular response to insulin stimulus biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0043066 negative regulation of apoptotic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K located_in GO:0043197 dendritic spine cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0045807 positive regulation of endocytosis biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0051965 positive regulation of synapse assembly biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0061003 positive regulation of dendritic spine morphogenesis biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0071277 cellular response to calcium ion biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0071320 cellular response to cAMP biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0071454 cellular response to anoxia biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K is_active_in GO:0098978 glutamatergic synapse cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:0140245 regulation of translation at postsynapse biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:1990416 cellular response to brain-derived neurotrophic factor stimulus biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K involved_in GO:1990637 response to prolactin biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70531|ensembl:ENSRNOP00000022726 9606 Homo sapiens Ensembl Eukaryotic elongation factor 2 kinase 20260529 UniProtKB O00418 EEF2K enables GO:0004686 elongation factor-2 kinase activity molecular_function ECO:0000269 EXP PMID:11015200 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20230412 UniProtKB O00418 EEF2K involved_in GO:0046777 protein autophosphorylation biological_process ECO:0000314 IDA PMID:23184662 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20150123 UniProtKB O00418 EEF2K located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-165758 9606 Homo sapiens Reactome Eukaryotic elongation factor 2 kinase 20130503 UniProtKB O00418 EEF2K enables GO:0004686 elongation factor-2 kinase activity molecular_function ECO:0000314 IDA PMID:9144159 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20110912 UniProtKB O00418 EEF2K enables GO:0005516 calmodulin binding molecular_function ECO:0000314 IDA PMID:9144159 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20110912 UniProtKB O00418 EEF2K involved_in GO:0046777 protein autophosphorylation biological_process ECO:0000314 IDA PMID:9144159 9606 Homo sapiens UniProt Eukaryotic elongation factor 2 kinase 20110912 UniProtKB O00418 EEF2K enables GO:0004672 protein kinase activity molecular_function ECO:0000304 TAS PMID:9144159 9606 Homo sapiens PINC Eukaryotic elongation factor 2 kinase 20030904 UniProtKB O00418 EEF2K located_in GO:0005737 cytoplasm cellular_component ECO:0000304 TAS PMID:9144159 9606 Homo sapiens PINC Eukaryotic elongation factor 2 kinase 20030904 UniProtKB O00418 EEF2K involved_in GO:0006414 translational elongation biological_process ECO:0000304 TAS PMID:9144159 9606 Homo sapiens PINC Eukaryotic elongation factor 2 kinase 20030904 UniProtKB O00418 EEF2K enables GO:0008135 translation factor activity, RNA binding molecular_function ECO:0000304 TAS PMID:9144159 9606 Homo sapiens PINC Eukaryotic elongation factor 2 kinase 20030904