GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB O75477 ERLIN1 is_active_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000794169|UniProtKB:O75477|UniProtKB:O94905|WB:WBGene00016592 9606 Homo sapiens GO_Central Erlin-1 20170228 UniProtKB O75477 ERLIN1 enables GO:0015485 cholesterol binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000794169|UniProtKB:O75477 9606 Homo sapiens GO_Central Erlin-1 20170228 UniProtKB O75477 ERLIN1 involved_in GO:0032933 SREBP signaling pathway biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000794169|UniProtKB:O75477|UniProtKB:O94905 9606 Homo sapiens GO_Central Erlin-1 20170228 UniProtKB O75477 ERLIN1 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000256 IEA GO_REF:0000002 InterPro:IPR033294 9606 Homo sapiens InterPro Erlin-1 20260601 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00028685|UniProtKB-SubCell:SL-0097 9606 Homo sapiens UniProt Erlin-1 20260601 UniProtKB O75477 ERLIN1 enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR033294 9606 Homo sapiens InterPro Erlin-1 20260601 UniProtKB O75477 ERLIN1 involved_in GO:0032933 SREBP signaling pathway biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00087340 9606 Homo sapiens UniProt Erlin-1 20260601 UniProtKB O75477 ERLIN1 part_of GO:0032991 protein-containing complex cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00028902 9606 Homo sapiens UniProt Erlin-1 20260601 UniProtKB O75477 ERLIN1 involved_in GO:0036503 ERAD pathway biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00029018 9606 Homo sapiens UniProt Erlin-1 20260601 UniProtKB O75477 ERLIN1 involved_in GO:0045541 negative regulation of cholesterol biosynthetic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00085017 9606 Homo sapiens UniProt Erlin-1 20260601 UniProtKB O75477 ERLIN1 involved_in GO:0045717 negative regulation of fatty acid biosynthetic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00084177 9606 Homo sapiens UniProt Erlin-1 20260601 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21343306 UniProtKB:O94905 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21343306 UniProtKB:Q86TM6 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21343306 UniProtKB:Q9UKV5 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22119785 UniProtKB:O94905 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22119785 UniProtKB:Q86TM6 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22119785 UniProtKB:Q9UKV5 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:B2RDE6 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q8N511 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q8TD06 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q96IW7 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q7Z4R8 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30021884 UniProtKB:O94905 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q12982 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q15436 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q7L5A8 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8N0V3 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8TD06 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q96IW7 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:O94905 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q7Z4R8 9606 Homo sapiens IntAct Erlin-1 20260530 UniProtKB O75477 ERLIN1 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Erlin-1 20251115 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866542 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866546 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866551 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866854 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866856 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-8866857 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9931264 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9931298 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-9931313 9606 Homo sapiens Reactome Erlin-1 20250925 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:19240031 9606 Homo sapiens ComplexPortal Erlin-1 20240823 UniProtKB O75477 ERLIN1 involved_in GO:0036503 ERAD pathway biological_process ECO:0000314 IDA PMID:19240031 9606 Homo sapiens ComplexPortal Erlin-1 20240823 UniProtKB O75477 ERLIN1 located_in GO:0045121 membrane raft cellular_component ECO:0005547 NAS PMID:34572057 9606 Homo sapiens ComplexPortal Erlin-1 20240823 UniProtKB O75477 ERLIN1 involved_in GO:0045540 regulation of cholesterol biosynthetic process biological_process ECO:0000314 IDA PMID:24217618 9606 Homo sapiens ComplexPortal Erlin-1 20240823 UniProtKB O75477 ERLIN1 part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:18468998 9606 Homo sapiens MGI Erlin-1 20180219 UniProtKB O75477 ERLIN1 enables GO:0015485 cholesterol binding molecular_function ECO:0000314 IDA PMID:24217618 9606 Homo sapiens UniProt Erlin-1 20150504 UniProtKB O75477 ERLIN1 involved_in GO:0032933 SREBP signaling pathway biological_process ECO:0000315 IMP PMID:24217618 9606 Homo sapiens UniProt Erlin-1 20150504 UniProtKB O75477 ERLIN1 involved_in GO:0045541 negative regulation of cholesterol biosynthetic process biological_process ECO:0000315 IMP PMID:24217618 9606 Homo sapiens UniProt Erlin-1 20150504 UniProtKB O75477 ERLIN1 involved_in GO:0045717 negative regulation of fatty acid biosynthetic process biological_process ECO:0000315 IMP PMID:24217618 9606 Homo sapiens UniProt Erlin-1 20150504 UniProtKB O75477 ERLIN1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19240031 UniProtKB:O94905 9606 Homo sapiens UniProt Erlin-1 20090909 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:19240031 9606 Homo sapiens UniProt Erlin-1 20090909 UniProtKB O75477 ERLIN1 involved_in GO:0036503 ERAD pathway biological_process ECO:0000314 IDA PMID:19240031 9606 Homo sapiens UniProt Erlin-1 20090909 UniProtKB O75477 ERLIN1 located_in GO:0005789 endoplasmic reticulum membrane cellular_component ECO:0000314 IDA PMID:16835267 9606 Homo sapiens UniProt Erlin-1 20070911