GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q9UKT4 FBXO5 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0017551|MGI:MGI:1926053|PANTHER:PTN000398158|UniProtKB:Q90Z80|UniProtKB:Q9UKT4 9606 Homo sapiens GO_Central F-box only protein 5 20250903 UniProtKB Q9UKT4 FBXO5 involved_in GO:0007088 regulation of mitotic nuclear division biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000398158|UniProtKB:Q90Z80|UniProtKB:Q9UKT4|ZFIN:ZDB-GENE-030131-4027 9606 Homo sapiens GO_Central F-box only protein 5 20250903 UniProtKB Q9UKT4 FBXO5 involved_in GO:0045835 negative regulation of meiotic nuclear division biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1914391|MGI:MGI:1926053|PANTHER:PTN000398158 9606 Homo sapiens GO_Central F-box only protein 5 20170228 UniProtKB Q9UKT4 FBXO5 located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt F-box only protein 5 20260601 UniProtKB Q9UKT4 FBXO5 located_in GO:0005737 cytoplasm cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:Q7TSG3|ensembl:ENSMUSP00000019907|UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt F-box only protein 5 20260601 UniProtKB Q9UKT4 FBXO5 located_in GO:0005819 spindle cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0251 9606 Homo sapiens UniProt F-box only protein 5 20260601 UniProtKB Q9UKT4 FBXO5 involved_in GO:0007088 regulation of mitotic nuclear division biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR047147 9606 Homo sapiens InterPro F-box only protein 5 20260601 UniProtKB Q9UKT4 FBXO5 involved_in GO:0010948 negative regulation of cell cycle process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027265 9606 Homo sapiens UniProt F-box only protein 5 20260601 UniProtKB Q9UKT4 FBXO5 involved_in GO:0045835 negative regulation of meiotic nuclear division biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR047147 9606 Homo sapiens InterPro F-box only protein 5 20260601 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16439210 UniProtKB:O60447 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17380122 UniProtKB:P63208 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17719540 UniProtKB:P30260 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18662541 UniProtKB:P30260 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27705803 UniProtKB:P63208 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P63208 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P30260 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P63208 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:P63208 9606 Homo sapiens IntAct F-box only protein 5 20260530 UniProtKB Q9UKT4 FBXO5 involved_in GO:0007346 regulation of mitotic cell cycle biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q7TSG3|ensembl:ENSMUSP00000019907 9606 Homo sapiens Ensembl F-box only protein 5 20260529 UniProtKB Q9UKT4 FBXO5 located_in GO:0072687 meiotic spindle cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q7TSG3|ensembl:ENSMUSP00000019907 9606 Homo sapiens Ensembl F-box only protein 5 20260529 UniProtKB Q9UKT4 FBXO5 involved_in GO:0016567 protein ubiquitination biological_process ECO:0007322 IEA GO_REF:0000041 UniPathway:UPA00143 9606 Homo sapiens UniProt F-box only protein 5 20260227 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA F-box only protein 5 20251115 UniProtKB Q9UKT4 FBXO5 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0005547 NAS PMID:34445249 9606 Homo sapiens ComplexPortal F-box only protein 5 20251014 UniProtKB Q9UKT4 FBXO5 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:34445249 9606 Homo sapiens ComplexPortal F-box only protein 5 20251014 UniProtKB Q9UKT4 FBXO5 involved_in GO:0045841 negative regulation of mitotic metaphase/anaphase transition biological_process ECO:0000314 IDA PMID:15148369 9606 Homo sapiens UniProt F-box only protein 5 20250722 UniProtKB Q9UKT4 FBXO5 enables GO:1990948 ubiquitin ligase inhibitor activity molecular_function ECO:0000314 IDA PMID:15148369 9606 Homo sapiens UniProt F-box only protein 5 20250722 UniProtKB Q9UKT4 FBXO5 involved_in GO:0006974 DNA damage response biological_process ECO:0000315 IMP PMID:17875940 9606 Homo sapiens UniProt F-box only protein 5 20230110 UniProtKB Q9UKT4 FBXO5 enables GO:0140678 molecular function inhibitor activity molecular_function ECO:0000314 IDA PMID:23708605 9606 Homo sapiens DisProt F-box only protein 5 20220214 UniProtKB Q9UKT4 FBXO5 enables GO:0140678 molecular function inhibitor activity molecular_function ECO:0000315 IMP PMID:23708605 9606 Homo sapiens DisProt F-box only protein 5 20220214 UniProtKB Q9UKT4 FBXO5 located_in GO:0072687 meiotic spindle cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q7TSG3 9606 Homo sapiens UniProt F-box only protein 5 20180831 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11988738 UniProtKB:Q12834 9606 Homo sapiens UniProt F-box only protein 5 20180824 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16921029 UniProtKB:Q9UM11 9606 Homo sapiens UniProt F-box only protein 5 20180824 UniProtKB Q9UKT4 FBXO5 enables GO:0010997 anaphase-promoting complex binding molecular_function ECO:0000314 IDA PMID:16921029 9606 Homo sapiens UniProt F-box only protein 5 20180824 UniProtKB Q9UKT4 FBXO5 involved_in GO:1904667 negative regulation of ubiquitin protein ligase activity biological_process ECO:0000315 IMP PMID:29875408 9606 Homo sapiens UniProt F-box only protein 5 20180822 UniProtKB Q9UKT4 FBXO5 enables GO:0010997 anaphase-promoting complex binding molecular_function ECO:0000314 IDA PMID:26083744 9606 Homo sapiens UniProt F-box only protein 5 20180820 UniProtKB Q9UKT4 FBXO5 involved_in GO:1904667 negative regulation of ubiquitin protein ligase activity biological_process ECO:0000315 IMP PMID:23708605 9606 Homo sapiens UniProt F-box only protein 5 20180820 UniProtKB Q9UKT4 FBXO5 involved_in GO:0051444 negative regulation of ubiquitin-protein transferase activity biological_process ECO:0000314 IDA PMID:23708001 9606 Homo sapiens UniProt F-box only protein 5 20180816 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23708001 UniProtKB:O75496|UniProtKB:P30260|UniProtKB:Q9UJX2|UniProtKB:Q9UJX6|UniProtKB:Q9UM11 9606 Homo sapiens UniProt F-box only protein 5 20180815 UniProtKB Q9UKT4 FBXO5 involved_in GO:0006275 regulation of DNA replication biological_process ECO:0000315 IMP PMID:17485488 9606 Homo sapiens UniProt F-box only protein 5 20180814 UniProtKB Q9UKT4 FBXO5 involved_in GO:0010971 positive regulation of G2/M transition of mitotic cell cycle biological_process ECO:0000315 IMP PMID:17485488 9606 Homo sapiens UniProt F-box only protein 5 20180814 UniProtKB Q9UKT4 FBXO5 involved_in GO:0032876 negative regulation of DNA endoreduplication biological_process ECO:0000315 IMP PMID:17875940 9606 Homo sapiens UniProt F-box only protein 5 20180814 UniProtKB Q9UKT4 FBXO5 involved_in GO:2000773 negative regulation of cellular senescence biological_process ECO:0000315 IMP PMID:17875940 9606 Homo sapiens UniProt F-box only protein 5 20180814 UniProtKB Q9UKT4 FBXO5 involved_in GO:0006275 regulation of DNA replication biological_process ECO:0000315 IMP PMID:17234884 9606 Homo sapiens UniProt F-box only protein 5 20180813 UniProtKB Q9UKT4 FBXO5 involved_in GO:0008284 positive regulation of cell population proliferation biological_process ECO:0000315 IMP PMID:17234884 9606 Homo sapiens UniProt F-box only protein 5 20180813 UniProtKB Q9UKT4 FBXO5 involved_in GO:0045669 positive regulation of osteoblast differentiation biological_process ECO:0000315 IMP PMID:29850565 9606 Homo sapiens UniProt F-box only protein 5 20180718 UniProtKB Q9UKT4 FBXO5 involved_in GO:0070169 positive regulation of biomineral tissue development biological_process ECO:0000315 IMP PMID:29850565 9606 Homo sapiens UniProt F-box only protein 5 20180718 UniProtKB Q9UKT4 FBXO5 involved_in GO:1905322 positive regulation of mesenchymal stem cell migration biological_process ECO:0000315 IMP PMID:29850565 9606 Homo sapiens UniProt F-box only protein 5 20180718 UniProtKB Q9UKT4 FBXO5 involved_in GO:0045841 negative regulation of mitotic metaphase/anaphase transition biological_process ECO:0000314 IDA PMID:11988738 9606 Homo sapiens UniProt F-box only protein 5 20180619 UniProtKB Q9UKT4 FBXO5 involved_in GO:0045841 negative regulation of mitotic metaphase/anaphase transition biological_process ECO:0000314 IDA PMID:16921029 9606 Homo sapiens UniProt F-box only protein 5 20180619 UniProtKB Q9UKT4 FBXO5 involved_in GO:1904667 negative regulation of ubiquitin protein ligase activity biological_process ECO:0000314 IDA PMID:11988738 9606 Homo sapiens UniProt F-box only protein 5 20180619 UniProtKB Q9UKT4 FBXO5 involved_in GO:1904667 negative regulation of ubiquitin protein ligase activity biological_process ECO:0000314 IDA PMID:16921029 9606 Homo sapiens UniProt F-box only protein 5 20180619 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-163010 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-174097 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-174122 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-174174 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-174235 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-8961699 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-174159 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-174203 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-174209 9606 Homo sapiens Reactome F-box only protein 5 20130503 UniProtKB Q9UKT4 FBXO5 enables GO:0019901 protein kinase binding molecular_function ECO:0000353 IPI PMID:15148369 UniProtKB:P06493 9606 Homo sapiens UniProt F-box only protein 5 20111124 UniProtKB Q9UKT4 FBXO5 enables GO:0019901 protein kinase binding molecular_function ECO:0000353 IPI PMID:15148369 UniProtKB:P53350 9606 Homo sapiens UniProt F-box only protein 5 20111124 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11988738 UniProtKB:Q9UM11 9606 Homo sapiens UniProt F-box only protein 5 20060929 UniProtKB Q9UKT4 FBXO5 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12791267 UniProtKB:Q9Y297 9606 Homo sapiens UniProt F-box only protein 5 20060929 UniProtKB Q9UKT4 FBXO5 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:11988738 9606 Homo sapiens UniProt F-box only protein 5 20060929 UniProtKB Q9UKT4 FBXO5 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:11988738 9606 Homo sapiens UniProt F-box only protein 5 20060929 UniProtKB Q9UKT4 FBXO5 located_in GO:0005819 spindle cellular_component ECO:0000314 IDA PMID:15469984 9606 Homo sapiens UniProt F-box only protein 5 20060929 UniProtKB Q9UKT4 FBXO5 involved_in GO:0007346 regulation of mitotic cell cycle biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q7TSG3 9606 Homo sapiens UniProt F-box only protein 5 20060929