GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q969H0 FBXW7 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:104810|MGI:MGI:1354695|PANTHER:PTN000457424|PomBase:SPBC887.04c|SGD:S000001696|UniProtKB:Q57YN4|UniProtKB:Q969H0|UniProtKB:Q9Y263 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 7 20251219 UniProtKB Q969H0 FBXW7 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:104810|MGI:MGI:1354695|PANTHER:PTN000457424|PomBase:SPBC887.04c|SGD:S000001696|UniProtKB:Q969H0|UniProtKB:Q9Y263|WB:WBGene00007333 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 7 20251219 UniProtKB Q969H0 FBXW7 involved_in GO:0010992 ubiquitin recycling biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000457424|SGD:S000001696 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 7 20170228 UniProtKB Q969H0 FBXW7 enables GO:0043130 ubiquitin binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000457424|SGD:S000001696 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 7 20170228 UniProtKB Q969H0 FBXW7 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1354695|PANTHER:PTN000457424|PomBase:SPBC887.04c|SGD:S000001696|UniProtKB:Q969H0 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 7 20170228 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0190 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 located_in GO:0005694 chromosome cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0468 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 located_in GO:0005730 nucleolus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0188 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 located_in GO:0005737 cytoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00084384 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:0042752 regulation of circadian rhythm biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00088520 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:0048731 system development biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027702 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:1901800 positive regulation of proteasomal protein catabolic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00091269 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00088649 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00087687 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 involved_in GO:2001205 negative regulation of osteoclast development biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00088112 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260601 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15070733 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17157259 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17314511 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17909182 UniProtKB:P46531 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17909182 UniProtKB:Q91LX9 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19111882 UniProtKB:P04198 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19412162 UniProtKB:P63208-1 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20596027 UniProtKB:P63208-1 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20823234 UniProtKB:P46531 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21145461 UniProtKB:Q13616 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21620836 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22307056 UniProtKB:Q9Z0Z7 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22939624 UniProtKB:P08238 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23022380 UniProtKB:P46531 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23108047 UniProtKB:Q13616 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23108047 UniProtKB:Q16204 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23791182 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23791182 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24412244 UniProtKB:P01112 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24412244 UniProtKB:P31749 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24412244 UniProtKB:Q00597 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24412244 UniProtKB:Q15797 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25344755 UniProtKB:P46531 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27229929 UniProtKB:P46531 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27880917 UniProtKB:Q8WUJ0 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28007894 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28007894 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28007894 UniProtKB:Q8WUJ0 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q13616 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q13616 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34591642 UniProtKB:Q13616 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35140242 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P01112 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P04198 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P08238 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P11802 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P24385 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P31749 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P42345 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P46527 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:P52333 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:Q00597 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:Q15797 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:Q16539 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:Q9NR00 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:Q13616 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0-1 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28007894 UniProtKB:Q8WUJ0 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:21620836 UniProtKB:Q969H0 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:23791182 UniProtKB:Q969H0 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:35512704 UniProtKB:Q969H0 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 7 20260530 UniProtKB Q969H0 FBXW7 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000316 IGI PMID:40274799 UniProtKB:A6NLP5 9606 Homo sapiens FlyBase F-box/WD repeat-containing protein 7 20260522 UniProtKB Q969H0 FBXW7 involved_in GO:0016567 protein ubiquitination biological_process ECO:0007322 IEA GO_REF:0000041 UniPathway:UPA00143 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20260227 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA F-box/WD repeat-containing protein 7 20251115 UniProtKB Q969H0 FBXW7 located_in GO:0005694 chromosome cellular_component ECO:0000269 EXP PMID:26774286 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20251027 UniProtKB Q969H0 FBXW7 located_in GO:0005737 cytoplasm cellular_component ECO:0000269 EXP PMID:17558397 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20251027 UniProtKB Q969H0 FBXW7 located_in GO:0005737 cytoplasm cellular_component ECO:0000269 EXP PMID:28007894 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20251027 UniProtKB Q969H0 FBXW7 involved_in GO:0007346 regulation of mitotic cell cycle biological_process ECO:0005547 NAS PMID:36395886 9606 Homo sapiens ComplexPortal F-box/WD repeat-containing protein 7 20251014 UniProtKB Q969H0 FBXW7 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0005547 NAS PMID:34445249 9606 Homo sapiens ComplexPortal F-box/WD repeat-containing protein 7 20251014 UniProtKB Q969H0 FBXW7 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:34445249 9606 Homo sapiens ComplexPortal F-box/WD repeat-containing protein 7 20251014 UniProtKB Q969H0 FBXW7 involved_in GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q8VBV4 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20250221 UniProtKB Q969H0 FBXW7 involved_in GO:0045746 negative regulation of Notch signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q8VBV4 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20250221 UniProtKB Q969H0 FBXW7 involved_in GO:0050821 protein stabilization biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q8VBV4 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20250221 UniProtKB Q969H0 FBXW7 acts_upstream_of GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q8VBV4 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20250221 UniProtKB Q969H0 FBXW7 involved_in GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q8VBV4 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20250221 UniProtKB Q969H0 FBXW7 is_active_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:17558397 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20250217 UniProtKB Q969H0 FBXW7 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0000314 IDA PMID:15103331 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20250217 UniProtKB Q969H0 FBXW7 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000314 IDA PMID:15150404 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20250217 UniProtKB Q969H0 FBXW7 involved_in GO:1901524 regulation of mitophagy biological_process ECO:0000315 IMP PMID:24912190 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20230928 UniProtKB Q969H0 FBXW7 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000314 IDA PMID:34741373 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20230621 UniProtKB Q969H0-1 FBXW7 is_active_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:17558397 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20230608 UniProtKB Q969H0-1 FBXW7 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0000314 IDA PMID:15103331 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20230608 UniProtKB Q969H0-1 FBXW7 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000314 IDA PMID:15150404 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20230608 UniProtKB Q969H0 FBXW7 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:35395208 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20221206 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27238018 UniProtKB:P20393 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20190117 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27238018 UniProtKB:Q3UV55 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20190117 UniProtKB Q969H0 FBXW7 involved_in GO:0042752 regulation of circadian rhythm biological_process ECO:0000315 IMP PMID:27238018 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20190117 UniProtKB Q969H0 FBXW7 involved_in GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:27238018 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20190117 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27458189 UniProtKB:P05412 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20181108 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27458189 UniProtKB:Q8TB68 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20181108 UniProtKB Q969H0 FBXW7 involved_in GO:0010629 negative regulation of gene expression biological_process ECO:0000315 IMP PMID:23823476 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20180723 UniProtKB Q969H0 FBXW7 involved_in GO:0010629 negative regulation of gene expression biological_process ECO:0000316 IGI PMID:23823476 RNAcentral:URS00001CC379_9606 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20180723 UniProtKB Q969H0-1 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28007894 UniProtKB:P63208|UniProtKB:Q13616 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180413 UniProtKB Q969H0-1 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28007894 UniProtKB:Q8WUJ0 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180413 UniProtKB Q969H0-1 FBXW7 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:28007894 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180413 UniProtKB Q969H0-1 FBXW7 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:28007894 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180413 UniProtKB Q969H0-1 FBXW7 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:28007894 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180413 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29149593 UniProtKB:P62877|UniProtKB:P63208|UniProtKB:Q04721|UniProtKB:Q13616 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180202 UniProtKB Q969H0 FBXW7 involved_in GO:2001205 negative regulation of osteoclast development biological_process ECO:0000315 IMP PMID:29149593 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20180202 UniProtKB Q969H0-1 FBXW7 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:25897075 9606 Homo sapiens ARUK-UCL F-box/WD repeat-containing protein 7 20171120 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27837025 UniProtKB:P04198 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20170622 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-2220967 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20170612 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-NUL-2064853 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20170612 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-NUL-2064883 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20170612 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-NUL-9604628 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20170612 UniProtKB Q969H0 FBXW7 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:17434132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20151217 UniProtKB Q969H0 FBXW7 enables GO:0030332 cyclin binding molecular_function ECO:0000353 IPI PMID:17434132 UniProtKB:P24864 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20151217 UniProtKB Q969H0 FBXW7 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000314 IDA PMID:17434132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20151217 UniProtKB Q969H0 FBXW7 enables GO:0050816 phosphothreonine residue binding molecular_function ECO:0000314 IDA PMID:17434132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20151217 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24344117 UniProtKB:Q9H4H8 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20150911 UniProtKB Q969H0 FBXW7 involved_in GO:1903749 positive regulation of protein localization to mitochondrion biological_process ECO:0000315 IMP PMID:24912190 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20150421 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24000165 UniProtKB:A1L167 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20150408 UniProtKB Q969H0 FBXW7 enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000353 IPI PMID:12628165 UniProtKB:O60260 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20150310 UniProtKB Q969H0 FBXW7 involved_in GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway biological_process ECO:0000314 IDA PMID:23858059 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140826 UniProtKB Q969H0 FBXW7 part_of GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex cellular_component ECO:0000353 IPI PMID:12628165 UniProtKB:O60260 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140807 UniProtKB Q969H0 FBXW7 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:12628165 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140804 UniProtKB Q969H0 FBXW7 enables GO:0030332 cyclin binding molecular_function ECO:0000314 IDA PMID:12628165 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140804 UniProtKB Q969H0 FBXW7 enables GO:0030674 protein-macromolecule adaptor activity molecular_function ECO:0000314 IDA PMID:12628165 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140804 UniProtKB Q969H0 FBXW7 involved_in GO:0031398 positive regulation of protein ubiquitination biological_process ECO:0000314 IDA PMID:12628165 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140804 UniProtKB Q969H0 FBXW7 enables GO:0097027 ubiquitin-protein transferase activator activity molecular_function ECO:0000314 IDA PMID:12628165 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140804 UniProtKB Q969H0 FBXW7 involved_in GO:1902806 regulation of cell cycle G1/S phase transition biological_process ECO:0000304 TAS PMID:12628165 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140804 UniProtKB Q969H0 FBXW7 enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000353 IPI PMID:12628165 UniProtKB:Q9WVS6 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140731 UniProtKB Q969H0 FBXW7 involved_in GO:1901800 positive regulation of proteasomal protein catabolic process biological_process ECO:0000314 IDA PMID:23858059 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140729 UniProtKB Q969H0 FBXW7 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:23858059 9606 Homo sapiens ParkinsonsUK-UCL F-box/WD repeat-containing protein 7 20140728 UniProtKB Q969H0 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-2220978 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130606 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8952618 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8952620 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8955241 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8955289 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8956040 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8956200 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983140 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983147 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983156 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0 FBXW7 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983157 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 7 20130528 UniProtKB Q969H0-1 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17873522 UniProtKB:P01106 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20111120 UniProtKB Q969H0-1 FBXW7 involved_in GO:0006974 DNA damage response biological_process ECO:0000314 IDA PMID:17873522 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20111120 UniProtKB Q969H0-1 FBXW7 part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:17873522 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20111120 UniProtKB Q969H0-1 FBXW7 involved_in GO:0034644 cellular response to UV biological_process ECO:0000314 IDA PMID:17873522 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20111120 UniProtKB Q969H0 FBXW7 involved_in GO:2000639 negative regulation of SREBP signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110801 UniProtKB Q969H0 FBXW7 involved_in GO:0001944 vasculature development biological_process ECO:0000304 TAS PMID:21123947 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 involved_in GO:0010868 negative regulation of triglyceride biosynthetic process biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 involved_in GO:0010883 regulation of lipid storage biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 involved_in GO:0032880 regulation of protein localization biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 involved_in GO:0045746 negative regulation of Notch signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 involved_in GO:0055088 lipid homeostasis biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 involved_in GO:2000346 negative regulation of hepatocyte proliferation biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q0VGT7 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20110420 UniProtKB Q969H0 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15103331 UniProtKB:P01106 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20100607 UniProtKB Q969H0-1 FBXW7 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17558397 UniProtKB:Q96RU2 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20100607 UniProtKB Q969H0-1 FBXW7 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA PMID:17558397 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20100607 UniProtKB Q969H0 FBXW7 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000314 IDA PMID:15103331 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20100607 UniProtKB Q969H0 FBXW7 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:15103331 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20100607 UniProtKB Q969H0 FBXW7 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000314 IDA PMID:15103331 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 7 20100607 UniProtKB Q969H0 FBXW7 involved_in GO:0007062 sister chromatid cohesion biological_process ECO:0000315 IMP PMID:15917200 9606 Homo sapiens BHF-UCL F-box/WD repeat-containing protein 7 20100127 UniProtKB Q969H0 FBXW7 acts_upstream_of_or_within GO:0016567 protein ubiquitination biological_process ECO:0000314 IDA PMID:12354302 9606 Homo sapiens MGI F-box/WD repeat-containing protein 7 20030212