GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q8N3Y1 FBXW8 involved_in GO:0060271 cilium assembly biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1917485|MGI:MGI:1918511|PANTHER:PTN002541592|UniProtKB:Q8TC44|ZFIN:ZDB-GENE-031118-54 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 8 20240801 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1923041|PANTHER:PTN000520403|UniProtKB:Q8N3Y1 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 8 20221009 UniProtKB Q8N3Y1 FBXW8 part_of GO:0031467 Cul7-RING ubiquitin ligase complex cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1923041|PANTHER:PTN000520403|UniProtKB:Q8N3Y1 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 8 20221009 UniProtKB Q8N3Y1 FBXW8 is_active_in GO:0005814 centriole cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002541592|UniProtKB:Q8NBT0|UniProtKB:Q8TC44 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 8 20210811 UniProtKB Q8N3Y1 FBXW8 is_active_in GO:0036064 ciliary basal body cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002541592|UniProtKB:Q8NBT0|UniProtKB:Q8TC44 9606 Homo sapiens GO_Central F-box/WD repeat-containing protein 8 20210811 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005737 cytoplasm cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026971|UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20260601 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005794 Golgi apparatus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20260601 UniProtKB Q8N3Y1 FBXW8 located_in GO:0048471 perinuclear region of cytoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0198 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20260601 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15070733 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 8 20260530 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17314511 UniProtKB:P01106 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 8 20260530 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27705803 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 8 20260530 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 8 20260530 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:P63208 9606 Homo sapiens IntAct F-box/WD repeat-containing protein 8 20260530 UniProtKB Q8N3Y1 FBXW8 is_active_in GO:0005829 cytosol cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012 9606 Homo sapiens Ensembl F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012 9606 Homo sapiens Ensembl F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000501 IEA GO_REF:0000120 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012|UniPathway:UPA00143 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012 9606 Homo sapiens Ensembl F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 part_of GO:0031467 Cul7-RING ubiquitin ligase complex cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012 9606 Homo sapiens Ensembl F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012 9606 Homo sapiens Ensembl F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BIA4|ensembl:ENSMUSP00000047012 9606 Homo sapiens Ensembl F-box/WD repeat-containing protein 8 20260529 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA F-box/WD repeat-containing protein 8 20251115 UniProtKB Q8N3Y1 FBXW8 part_of GO:0019005 SCF ubiquitin ligase complex cellular_component ECO:0005547 NAS PMID:35982156 9606 Homo sapiens ComplexPortal F-box/WD repeat-containing protein 8 20251014 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:35982156 9606 Homo sapiens ComplexPortal F-box/WD repeat-containing protein 8 20251014 UniProtKB Q8N3Y1 FBXW8 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:18498745 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20250220 UniProtKB Q8N3Y1 FBXW8 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:17205132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20250211 UniProtKB Q8N3Y1 FBXW8 part_of GO:0031467 Cul7-RING ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:17205132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20250211 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0000314 IDA PMID:17205132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20250211 UniProtKB Q8N3Y1 FBXW8 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000314 IDA PMID:17205132 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20250211 UniProtKB Q8N3Y1 FBXW8 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000314 IDA PMID:24362026 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20250211 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0046627 negative regulation of insulin receptor signaling pathway biological_process ECO:0000314 IDA PMID:18498745 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20240924 UniProtKB Q8N3Y1 FBXW8 is_active_in GO:0005829 cytosol cellular_component ECO:0000314 IDA PMID:18498745 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20240920 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000314 IDA PMID:18498745 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20240920 UniProtKB Q8N3Y1 FBXW8 enables GO:1990756 ubiquitin-like ligase-substrate adaptor activity molecular_function ECO:0000314 IDA PMID:18498745 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20240920 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18498745 UniProtKB:P35568 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24362026 UniProtKB:Q92918 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0008283 cell population proliferation biological_process ECO:0000314 IDA PMID:24362026 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000314 IDA PMID:24362026 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 part_of GO:0031467 Cul7-RING ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:18498745 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 part_of GO:0031467 Cul7-RING ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:24362026 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 colocalizes_with GO:1990393 3M complex cellular_component ECO:0000314 IDA PMID:24793695 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20140701 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21572988 UniProtKB:O35254 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130630 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0007030 Golgi organization biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P0DL28 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130621 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0007030 Golgi organization biological_process ECO:0000316 IGI PMID:21572988 UniProtKB:P0DL28 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130621 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0050775 positive regulation of dendrite morphogenesis biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P0DL28 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130621 UniProtKB Q8N3Y1 FBXW8 involved_in GO:0050775 positive regulation of dendrite morphogenesis biological_process ECO:0000314 IDA PMID:21572988 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130621 UniProtKB Q8N3Y1 FBXW8 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21572988 UniProtKB:O75147 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130531 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005794 Golgi apparatus cellular_component ECO:0000314 IDA PMID:21572988 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130531 UniProtKB Q8N3Y1 FBXW8 part_of GO:0031467 Cul7-RING ubiquitin ligase complex cellular_component ECO:0000314 IDA PMID:21572988 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130531 UniProtKB Q8N3Y1 FBXW8 located_in GO:0048471 perinuclear region of cytoplasm cellular_component ECO:0000314 IDA PMID:21572988 9606 Homo sapiens UniProt F-box/WD repeat-containing protein 8 20130530 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8952618 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8952620 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8955241 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8955289 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8956040 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8956200 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983140 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983147 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983156 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011 UniProtKB Q8N3Y1 FBXW8 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-983157 9606 Homo sapiens Reactome F-box/WD repeat-containing protein 8 20101011