GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q6Y7W6 GIGYF2 enables GO:0000900 mRNA regulatory element binding translation repressor activity molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0039936|PANTHER:PTN004461388 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20250805 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0045947 negative regulation of translational initiation biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN004461388|UniProtKB:Q6Y7W6 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20250805 UniProtKB Q6Y7W6 GIGYF2 is_active_in GO:0016020 membrane cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:2138584|PANTHER:PTN002683636 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20230110 UniProtKB Q6Y7W6 GIGYF2 is_active_in GO:0005829 cytosol cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN004461388|UniProtKB:Q6Y7W6 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20210217 UniProtKB Q6Y7W6 GIGYF2 is_active_in GO:0031982 vesicle cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:2138584|PANTHER:PTN002683636|UniProtKB:Q6Y7W6 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20210217 UniProtKB Q6Y7W6 GIGYF2 is_active_in GO:0043204 perikaryon cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:2138584|PANTHER:PTN002683636|UniProtKB:Q6Y7W6 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20210217 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0048009 insulin-like growth factor receptor signaling pathway biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:2138584|PANTHER:PTN002683636|UniProtKB:Q6Y7W6 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20210217 UniProtKB Q6Y7W6 GIGYF2 is_active_in GO:1990635 proximal dendrite cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:2138584|PANTHER:PTN002683636|UniProtKB:Q6Y7W6 9606 Homo sapiens GO_Central GRB10-interacting GYF protein 2 20210217 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15161933 UniProtKB:P63104 9606 Homo sapiens IntAct GRB10-interacting GYF protein 2 20260530 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28698298 UniProtKB:O60573-1 9606 Homo sapiens IntAct GRB10-interacting GYF protein 2 20260530 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:P63104 9606 Homo sapiens IntAct GRB10-interacting GYF protein 2 20260530 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0005737 cytoplasm cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q6Y7W8|ensembl:ENSMUSP00000027475 9606 Homo sapiens Ensembl GRB10-interacting GYF protein 2 20260529 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0016020 membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q6Y7W8|ensembl:ENSMUSP00000027475 9606 Homo sapiens Ensembl GRB10-interacting GYF protein 2 20260529 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0031982 vesicle cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q6Y7W8|ensembl:ENSMUSP00000027475 9606 Homo sapiens Ensembl GRB10-interacting GYF protein 2 20260529 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0043204 perikaryon cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q6Y7W8|ensembl:ENSMUSP00000027475 9606 Homo sapiens Ensembl GRB10-interacting GYF protein 2 20260529 UniProtKB Q6Y7W6 GIGYF2 located_in GO:1990635 proximal dendrite cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q6Y7W8|ensembl:ENSMUSP00000027475 9606 Homo sapiens Ensembl GRB10-interacting GYF protein 2 20260529 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA GRB10-interacting GYF protein 2 20251115 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:1990261 pre-mRNA catabolic process biological_process ECO:0005547 NAS PMID:33053355 9606 Homo sapiens ComplexPortal GRB10-interacting GYF protein 2 20250731 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0045947 negative regulation of translational initiation biological_process ECO:0000314 IDA PMID:32726578 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20230221 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0045947 negative regulation of translational initiation biological_process ECO:0000314 IDA PMID:35878012 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20230221 UniProtKB Q6Y7W6 GIGYF2 enables GO:0060090 molecular adaptor activity molecular_function ECO:0000314 IDA PMID:32726578 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20230221 UniProtKB Q6Y7W6 GIGYF2 enables GO:0060090 molecular adaptor activity molecular_function ECO:0000314 IDA PMID:35878012 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20230221 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0060339 negative regulation of type I interferon-mediated signaling pathway biological_process ECO:0000314 IDA PMID:35878012 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20230221 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:32726578 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20230221 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31439631 UniProtKB:O60573 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20210315 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31439631 UniProtKB:P26196 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20210315 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31439631 UniProtKB:P26651 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20210315 UniProtKB Q6Y7W6 GIGYF2 enables GO:0045296 cadherin binding molecular_function ECO:0007005 HDA PMID:25468996 9606 Homo sapiens BHF-UCL GRB10-interacting GYF protein 2 20180329 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20878056 UniProtKB:O75420|UniProtKB:P00533|UniProtKB:P31749|UniProtKB:Q13322|UniProtKB:Q92600 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20170522 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20878056 UniProtKB:Q13322|UniProtKB:Q92600 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20170522 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20878056 UniProtKB:Q92600 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20170522 UniProtKB Q6Y7W6 GIGYF2 part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:20878056 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20170522 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20670374 UniProtKB:Q13322 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:O94979 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:P11940 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:P26368 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:P54259 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:P55735 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:Q01081 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:Q14444 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:Q16637 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:Q6P2Q9 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20696395 UniProtKB:Q9Y4Z0 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27157137 UniProtKB:Q9UKV8 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0005768 endosome cellular_component ECO:0000314 IDA PMID:20670374 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:20696395 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0005794 Golgi apparatus cellular_component ECO:0000314 IDA PMID:20696395 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0010494 cytoplasmic stress granule cellular_component ECO:0000314 IDA PMID:20696395 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0016441 post-transcriptional gene silencing biological_process ECO:0000314 IDA PMID:27157137 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0043204 perikaryon cellular_component ECO:0000314 IDA PMID:20670374 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0048009 insulin-like growth factor receptor signaling pathway biological_process ECO:0000315 IMP PMID:20670374 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 involved_in GO:0061157 mRNA destabilization biological_process ECO:0000314 IDA PMID:27157137 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 enables GO:0070064 proline-rich region binding molecular_function ECO:0000314 IDA PMID:20696395 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:1990635 proximal dendrite cellular_component ECO:0000314 IDA PMID:20670374 9606 Homo sapiens ParkinsonsUK-UCL GRB10-interacting GYF protein 2 20161108 UniProtKB Q6Y7W6 GIGYF2 located_in GO:0016020 membrane cellular_component ECO:0007005 HDA PMID:19946888 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20140627 UniProtKB Q6Y7W6 GIGYF2 enables GO:0003723 RNA binding molecular_function ECO:0007005 HDA PMID:22681889 9606 Homo sapiens UniProt GRB10-interacting GYF protein 2 20140203 UniProtKB Q6Y7W6 GIGYF2 acts_upstream_of_or_within GO:0017148 negative regulation of translation biological_process ECO:0000315 IMP PMID:22751931 9606 Homo sapiens MGI GRB10-interacting GYF protein 2 20130211