GENE PRODUCT DB	GENE PRODUCT ID	SYMBOL	QUALIFIER	GO TERM	GO NAME	GO ASPECT	ECO ID	GO EVIDENCE CODE	REFERENCE	WITH/FROM	TAXON ID	TAXON NAME	ASSIGNED BY	GENE NAME	DATE
UniProtKB	Q9H000	MKRN2	involved_in	GO:0016567	protein ubiquitination	biological_process	ECO:0000318	IBA	GO_REF:0000033	PANTHER:PTN000131854|UniProtKB:Q9UHC7	9606	Homo sapiens	GO_Central	E3 ubiquitin-protein ligase makorin-2	20230110
UniProtKB	Q9H000	MKRN2	enables	GO:0061630	ubiquitin protein ligase activity	molecular_function	ECO:0000318	IBA	GO_REF:0000033	MGI:MGI:1914277|PANTHER:PTN000131854|UniProtKB:Q9UHC7	9606	Homo sapiens	GO_Central	E3 ubiquitin-protein ligase makorin-2	20211215
UniProtKB	Q9H000	MKRN2	involved_in	GO:0000209	protein polyubiquitination	biological_process	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR045072	9606	Homo sapiens	InterPro	E3 ubiquitin-protein ligase makorin-2	20260601
UniProtKB	Q9H000	MKRN2	located_in	GO:0005634	nucleus	cellular_component	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:Q9ERV1|ensembl:ENSMUSP00000000449|UniProtKB-SubCell:SL-0191	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20260601
UniProtKB	Q9H000	MKRN2	located_in	GO:0005737	cytoplasm	cellular_component	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:Q9ERV1|ensembl:ENSMUSP00000000449|UniProtKB-SubCell:SL-0086	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20260601
UniProtKB	Q9H000	MKRN2	enables	GO:0046872	metal ion binding	molecular_function	ECO:0000256	IEA	GO_REF:0000002	InterPro:IPR000571|InterPro:IPR036855	9606	Homo sapiens	InterPro	E3 ubiquitin-protein ligase makorin-2	20260601
UniProtKB	Q9H000	MKRN2	enables	GO:0061630	ubiquitin protein ligase activity	molecular_function	ECO:0000501	IEA	GO_REF:0000120	UniProtKB:Q9ERV1|ensembl:ENSMUSP00000000449|InterPro:IPR045072|EC:2.3.2.27	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20260601
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:17500595	UniProtKB:P42858	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:22046132	UniProtKB:P0C6X7-PRO_0000037311	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:25416956	UniProtKB:E9KL35	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:25416956	UniProtKB:P51668	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:25416956	UniProtKB:Q9NX04	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:25416956	UniProtKB:Q9Y2X8	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32296183	UniProtKB:O00303	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32296183	UniProtKB:P51668	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32296183	UniProtKB:P63244	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32296183	UniProtKB:Q9Y2X8	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32814053	UniProtKB:P42858	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32814053	UniProtKB:Q01658	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32814053	UniProtKB:Q13148	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32814053	UniProtKB:Q9Y5Q9	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:32838362	UniProtKB:P0DTD1-PRO_0000449621	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	enables	GO:0005515	protein binding	molecular_function	ECO:0000353	IPI	PMID:36217029	UniProtKB:P0DTD1-PRO_0000449621	9606	Homo sapiens	IntAct	E3 ubiquitin-protein ligase makorin-2	20260530
UniProtKB	Q9H000	MKRN2	involved_in	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	biological_process	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q9ERV1|ensembl:ENSMUSP00000000449	9606	Homo sapiens	Ensembl	E3 ubiquitin-protein ligase makorin-2	20260529
UniProtKB	Q9H000	MKRN2	involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	biological_process	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q9ERV1|ensembl:ENSMUSP00000000449	9606	Homo sapiens	Ensembl	E3 ubiquitin-protein ligase makorin-2	20260529
UniProtKB	Q9H000	MKRN2	involved_in	GO:1901223	negative regulation of non-canonical NF-kappaB signal transduction	biological_process	ECO:0000265	IEA	GO_REF:0000107	UniProtKB:Q9ERV1|ensembl:ENSMUSP00000000449	9606	Homo sapiens	Ensembl	E3 ubiquitin-protein ligase makorin-2	20260529
UniProtKB	Q9H000	MKRN2	involved_in	GO:0016567	protein ubiquitination	biological_process	ECO:0007322	IEA	GO_REF:0000041	UniPathway:UPA00143	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20260227
UniProtKB	Q9H000	MKRN2	located_in	GO:0005634	nucleus	cellular_component	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20231105
UniProtKB	Q9H000	MKRN2	located_in	GO:0005737	cytoplasm	cellular_component	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20231105
UniProtKB	Q9H000	MKRN2	enables	GO:0061630	ubiquitin protein ligase activity	molecular_function	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20231105
UniProtKB	Q9H000	MKRN2	involved_in	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20221025
UniProtKB	Q9H000	MKRN2	located_in	GO:0005634	nucleus	cellular_component	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20221025
UniProtKB	Q9H000	MKRN2	located_in	GO:0005737	cytoplasm	cellular_component	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20221025
UniProtKB	Q9H000	MKRN2	involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20221025
UniProtKB	Q9H000	MKRN2	enables	GO:0061630	ubiquitin protein ligase activity	molecular_function	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20221025
UniProtKB	Q9H000	MKRN2	involved_in	GO:1901223	negative regulation of non-canonical NF-kappaB signal transduction	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:Q9ERV1	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20221025
UniProtKB	Q9H000	MKRN2	involved_in	GO:0006351	DNA-templated transcription	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:B0F0H3	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20210628
UniProtKB	Q9H000	MKRN2	involved_in	GO:0043491	phosphatidylinositol 3-kinase/protein kinase B signal transduction	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:B0F0H3	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20210628
UniProtKB	Q9H000	MKRN2	involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	biological_process	ECO:0000250	ISS	GO_REF:0000024	UniProtKB:B0F0H3	9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20210628
UniProtKB	Q9H000	MKRN2	enables	GO:0003723	RNA binding	molecular_function	ECO:0007005	HDA	PMID:22681889		9606	Homo sapiens	UniProt	E3 ubiquitin-protein ligase makorin-2	20140203