GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q8TAT6 NPLOC4 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000295423|UniProtKB:Q8TAT6|WB:WBGene00019120|WB:WBGene00019121 9606 Homo sapiens GO_Central Nuclear protein localization protein 4 homolog 20251219 UniProtKB Q8TAT6 NPLOC4 enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000295423|RGD:620794 9606 Homo sapiens GO_Central Nuclear protein localization protein 4 homolog 20170228 UniProtKB Q8TAT6 NPLOC4 enables GO:0043130 ubiquitin binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000295423|RGD:620794 9606 Homo sapiens GO_Central Nuclear protein localization protein 4 homolog 20170228 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20260601 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0095 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20260601 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005829 cytosol cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0091 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20260601 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR016563 9606 Homo sapiens InterPro Nuclear protein localization protein 4 homolog 20260601 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0030970 retrograde protein transport, ER to cytosol biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00087984 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20260601 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17070805 UniProtKB:P0CG48 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18775313 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18775313 UniProtKB:Q92890 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20414249 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20414249 UniProtKB:Q92890 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21645854 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21645854 UniProtKB:Q92890 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26471729 UniProtKB:O95786 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26471729 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q4G0F5 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q92890 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P37173 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q0P6H9 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q92890 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:P0CG48 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:37776851 UniProtKB:P55072 9606 Homo sapiens IntAct Nuclear protein localization protein 4 homolog 20260530 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0007030 Golgi organization biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 contributes_to GO:0036435 K48-linked polyubiquitin modification-dependent protein binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 part_of GO:0036501 UFD1-NPL4 complex cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0036503 ERAD pathway biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 enables GO:0043130 ubiquitin binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 enables GO:0044877 protein-containing complex binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 enables GO:0051117 ATPase binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 contributes_to GO:0070530 K63-linked polyubiquitin modification-dependent protein binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9ES54|ensembl:ENSRNOP00000068982 9606 Homo sapiens Ensembl Nuclear protein localization protein 4 homolog 20260529 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0007322 IEA GO_REF:0000041 UniPathway:UPA00144 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20260227 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:33712450 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000353 IPI PMID:18775313 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000353 IPI PMID:20414249 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000353 IPI PMID:39329031 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0036503 ERAD pathway biological_process ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:39329031 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:1904949 ATPase complex cellular_component ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:1904949 ATPase complex cellular_component ECO:0005547 NAS PMID:33712450 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 part_of GO:1904949 ATPase complex cellular_component ECO:0005547 NAS PMID:39329031 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20251229 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Nuclear protein localization protein 4 homolog 20251115 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005634 nucleus cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9ES54 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20251027 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9ES54 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20251027 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0005547 NAS PMID:35452614 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20240823 UniProtKB Q8TAT6 NPLOC4 part_of GO:1990112 RQC complex cellular_component ECO:0005547 NAS PMID:35452614 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20240823 UniProtKB Q8TAT6 NPLOC4 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:35452614 9606 Homo sapiens ComplexPortal Nuclear protein localization protein 4 homolog 20240823 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9755507 9606 Homo sapiens Reactome Nuclear protein localization protein 4 homolog 20211008 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9758088 9606 Homo sapiens Reactome Nuclear protein localization protein 4 homolog 20211008 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9758090 9606 Homo sapiens Reactome Nuclear protein localization protein 4 homolog 20211008 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948427 9606 Homo sapiens Reactome Nuclear protein localization protein 4 homolog 20211008 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:26471729 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20170110 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0032480 negative regulation of type I interferon production biological_process ECO:0000315 IMP PMID:26471729 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20170110 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000314 IDA PMID:26471729 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20170110 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0039536 negative regulation of RIG-I signaling pathway biological_process ECO:0000315 IMP PMID:26471729 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20170110 UniProtKB Q8TAT6 NPLOC4 part_of GO:0036501 UFD1-NPL4 complex cellular_component ECO:0000353 IPI PMID:11574150 UniProtKB:Q92890 9606 Homo sapiens ParkinsonsUK-UCL Nuclear protein localization protein 4 homolog 20150521 UniProtKB Q8TAT6 NPLOC4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11574150 UniProtKB:Q92890 9606 Homo sapiens HGNC-UCL Nuclear protein localization protein 4 homolog 20150421 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0030970 retrograde protein transport, ER to cytosol biological_process ECO:0000315 IMP PMID:25660456 9606 Homo sapiens ParkinsonsUK-UCL Nuclear protein localization protein 4 homolog 20150421 UniProtKB Q8TAT6 NPLOC4 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9ES54 9606 Homo sapiens ParkinsonsUK-UCL Nuclear protein localization protein 4 homolog 20150421 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5654985 9606 Homo sapiens Reactome Nuclear protein localization protein 4 homolog 20141204 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5654989 9606 Homo sapiens Reactome Nuclear protein localization protein 4 homolog 20141204 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005634 nucleus cellular_component ECO:0007005 HDA PMID:21630459 9606 Homo sapiens UniProt Nuclear protein localization protein 4 homolog 20140320 UniProtKB Q8TAT6 NPLOC4 involved_in GO:0007030 Golgi organization biological_process ECO:0000250 ISS PMID:11574150 UniProtKB:Q9ES54 9606 Homo sapiens HGNC-UCL Nuclear protein localization protein 4 homolog 20070103 UniProtKB Q8TAT6 NPLOC4 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000250 ISS PMID:11574150 UniProtKB:P33755 9606 Homo sapiens HGNC-UCL Nuclear protein localization protein 4 homolog 20060221 UniProtKB Q8TAT6 NPLOC4 located_in GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network cellular_component ECO:0000250 ISS PMID:11574150 UniProtKB:P33755 9606 Homo sapiens HGNC-UCL Nuclear protein localization protein 4 homolog 20060221