GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB P07237 P4HB involved_in GO:0006457 protein folding biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000432607|RGD:619835|SGD:S000000548|SGD:S000002926|UniProtKB:C0H4Y6|UniProtKB:P07237|UniProtKB:Q53LQ0 9606 Homo sapiens GO_Central Protein disulfide-isomerase 20250903 UniProtKB P07237 P4HB is_active_in GO:0009897 external side of plasma membrane cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:97464|PANTHER:PTN000432883|UniProtKB:P07237 9606 Homo sapiens GO_Central Protein disulfide-isomerase 20181004 UniProtKB P07237 P4HB enables GO:0003756 protein disulfide isomerase activity molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:P04785|ensembl:ENSRNOP00000051841|InterPro:IPR005788|InterPro:IPR005792|EC:5.3.4.1 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260601 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:P09103|ensembl:ENSMUSP00000026122|UniProtKB-SubCell:SL-0095 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260601 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000501 IEA GO_REF:0000120 UniProtKB:P09103|ensembl:ENSMUSP00000026122|UniProtKB-SubCell:SL-0096 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260601 UniProtKB P07237 P4HB located_in GO:0005886 plasma membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0039 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260601 UniProtKB P07237 P4HB involved_in GO:0034975 protein folding in endoplasmic reticulum biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00084679 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260601 UniProtKB P07237 P4HB located_in GO:0042470 melanosome cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0161 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260601 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17055437 UniProtKB:Q03518 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19942855 UniProtKB:Q8TCT9 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20802462 UniProtKB:Q96HE7 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21057456 UniProtKB:Q13162 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24098548 UniProtKB:P10636-8 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26370502 UniProtKB:P28799 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30021884 UniProtKB:O15460 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31992623 UniProtKB:Q2GL86 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:O94818-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P01137 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P09228 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P26371 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P28799 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P60328 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P80188 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q14990 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q3LI67 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q52LG2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q5T7P3 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q5TA78 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q5TA82 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q63HM9 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q6PJG9 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8NE01 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8NEG0 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q92692-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9BYQ0 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9BYQ6 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9P121-3 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9P2K6 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9UC07-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9ULW2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9Y6H1 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32812023 UniProtKB:P10636-8 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O00444 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O15534 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:O43521 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P02538 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P17655 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P62873 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q09028 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q494V2-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q53R41 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q5T0J7-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q86WV1-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8N4N3-2 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8TAP6 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q8WUG5 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96B97 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96D03 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q96RK4 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:Q9NU02 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:O15460 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35063084 UniProtKB:P10636-8 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:O15460 9606 Homo sapiens IntAct Protein disulfide-isomerase 20260530 UniProtKB P07237 P4HB enables GO:0005178 integrin binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P09103|ensembl:ENSMUSP00000026122 9606 Homo sapiens Ensembl Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB located_in GO:0009897 external side of plasma membrane cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P09103|ensembl:ENSMUSP00000026122 9606 Homo sapiens Ensembl Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026550|UniProtKB:P09103|ensembl:ENSMUSP00000026122 9606 Homo sapiens UniProt Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB enables GO:0019899 enzyme binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P04785|ensembl:ENSRNOP00000051841 9606 Homo sapiens Ensembl Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB involved_in GO:0030070 insulin processing biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P09103|ensembl:ENSMUSP00000026122 9606 Homo sapiens Ensembl Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB part_of GO:0034663 endoplasmic reticulum chaperone complex cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P09103|ensembl:ENSMUSP00000026122 9606 Homo sapiens Ensembl Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB enables GO:0044877 protein-containing complex binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P04785|ensembl:ENSRNOP00000051841 9606 Homo sapiens Ensembl Protein disulfide-isomerase 20260529 UniProtKB P07237 P4HB involved_in GO:0030070 insulin processing biological_process ECO:0000304 TAS Reactome:R-HSA-264876 9606 Homo sapiens Reactome Protein disulfide-isomerase 20260316 UniProtKB P07237 P4HB involved_in GO:0035722 interleukin-12-mediated signaling pathway biological_process ECO:0000304 TAS Reactome:R-HSA-9020591 9606 Homo sapiens Reactome Protein disulfide-isomerase 20260316 UniProtKB P07237 P4HB involved_in GO:0038155 interleukin-23-mediated signaling pathway biological_process ECO:0000304 TAS Reactome:R-HSA-9020933 9606 Homo sapiens Reactome Protein disulfide-isomerase 20260316 UniProtKB P07237 P4HB enables GO:0003756 protein disulfide isomerase activity molecular_function ECO:0000269 EXP PMID:15720785 9606 Homo sapiens Reactome Protein disulfide-isomerase 20260222 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Protein disulfide-isomerase 20251115 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000269 EXP PMID:23475612 9606 Homo sapiens UniProt Protein disulfide-isomerase 20251027 UniProtKB P07237 P4HB enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000314 IDA PMID:21670307 9606 Homo sapiens UniProt Protein disulfide-isomerase 20241023 UniProtKB P07237 P4HB involved_in GO:2000406 positive regulation of T cell migration biological_process ECO:0000314 IDA PMID:21670307 9606 Homo sapiens UniProt Protein disulfide-isomerase 20241023 UniProtKB P07237 P4HB enables GO:0003756 protein disulfide isomerase activity molecular_function ECO:0000314 IDA PMID:32149426 9606 Homo sapiens UniProt Protein disulfide-isomerase 20240322 UniProtKB P07237 P4HB is_active_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:32149426 9606 Homo sapiens UniProt Protein disulfide-isomerase 20240322 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-264997 9606 Homo sapiens Reactome Protein disulfide-isomerase 20221107 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-3341296 9606 Homo sapiens Reactome Protein disulfide-isomerase 20221107 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-9817575 9606 Homo sapiens Reactome Protein disulfide-isomerase 20221107 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-1650808 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-174786 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-2002460 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-5358336 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-5358340 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-8866329 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-8948234 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-8950113 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-8950183 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-8950456 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-8952289 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-9737780 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB located_in GO:0005788 endoplasmic reticulum lumen cellular_component ECO:0000304 TAS Reactome:R-HSA-9918779 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000269 EXP PMID:21308844 9606 Homo sapiens Reactome Protein disulfide-isomerase 20220923 UniProtKB P07237 P4HB involved_in GO:0034975 protein folding in endoplasmic reticulum biological_process ECO:0000314 IDA PMID:21091435 9606 Homo sapiens FlyBase Protein disulfide-isomerase 20201009 UniProtKB P07237 P4HB enables GO:0003756 protein disulfide isomerase activity molecular_function ECO:0007122 IDA PMID:21091435 9606 Homo sapiens FlyBase Protein disulfide-isomerase 20200927 UniProtKB P07237 P4HB enables GO:0016972 thiol oxidase activity molecular_function ECO:0007122 IDA PMID:21091435 9606 Homo sapiens FlyBase Protein disulfide-isomerase 20200927 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16478722 UniProtKB:P55157 9606 Homo sapiens UniProt Protein disulfide-isomerase 20200825 UniProtKB P07237 P4HB involved_in GO:0045785 positive regulation of cell adhesion biological_process ECO:0000315 IMP PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191014 UniProtKB P07237 P4HB involved_in GO:1900026 positive regulation of substrate adhesion-dependent cell spreading biological_process ECO:0000315 IMP PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191014 UniProtKB P07237 P4HB enables GO:0003779 actin binding molecular_function ECO:0000353 IPI PMID:24415753 UniProtKB:P60709 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191010 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191010 UniProtKB P07237 P4HB located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191010 UniProtKB P07237 P4HB located_in GO:0005856 cytoskeleton cellular_component ECO:0000314 IDA PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191010 UniProtKB P07237 P4HB located_in GO:0030027 lamellipodium cellular_component ECO:0000314 IDA PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191010 UniProtKB P07237 P4HB part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:24415753 9606 Homo sapiens ARUK-UCL Protein disulfide-isomerase 20191010 UniProtKB P07237 P4HB enables GO:0015035 protein-disulfide reductase activity molecular_function ECO:0000314 IDA PMID:16677074 9606 Homo sapiens UniProt Protein disulfide-isomerase 20170301 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25108285 UniProtKB:P55157 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150928 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23475612 UniProtKB:P55157 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150925 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26224785 UniProtKB:P55157 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150925 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:23475612 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150925 UniProtKB P07237 P4HB enables GO:0046982 protein heterodimerization activity molecular_function ECO:0000314 IDA PMID:23475612 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150925 UniProtKB P07237 P4HB enables GO:0005178 integrin binding molecular_function ECO:0000353 IPI PMID:21670307 UniProtKB:P05106 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150720 UniProtKB P07237 P4HB involved_in GO:0046598 positive regulation of viral entry into host cell biological_process ECO:0000315 IMP PMID:21670307 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150625 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21670307 UniProtKB:O00182|UniProtKB:P30101|UniProtKB:Q15084 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150612 UniProtKB P07237 P4HB located_in GO:0009897 external side of plasma membrane cellular_component ECO:0000314 IDA PMID:21670307 9606 Homo sapiens UniProt Protein disulfide-isomerase 20150612 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23861867 UniProtKB:Q03463-PRO_0000278740 9606 Homo sapiens AgBase Protein disulfide-isomerase 20150115 UniProtKB P07237 P4HB located_in GO:0005925 focal adhesion cellular_component ECO:0007005 HDA PMID:21423176 9606 Homo sapiens UniProt Protein disulfide-isomerase 20140715 UniProtKB P07237 P4HB enables GO:0003723 RNA binding molecular_function ECO:0007005 HDA PMID:22658674 9606 Homo sapiens UniProt Protein disulfide-isomerase 20140203 UniProtKB P07237 P4HB enables GO:0003723 RNA binding molecular_function ECO:0007005 HDA PMID:22681889 9606 Homo sapiens UniProt Protein disulfide-isomerase 20140203 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:12095988 9606 Homo sapiens BHF-UCL Protein disulfide-isomerase 20131116 UniProtKB P07237 P4HB involved_in GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway biological_process ECO:0000315 IMP PMID:12095988 9606 Homo sapiens BHF-UCL Protein disulfide-isomerase 20131116 UniProtKB P07237 P4HB contributes_to GO:0004656 procollagen-proline 4-dioxygenase activity molecular_function ECO:0000314 IDA PMID:7753822 9606 Homo sapiens MGI Protein disulfide-isomerase 20131115 UniProtKB P07237 P4HB enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12095988 UniProtKB:Q9UMX0 9606 Homo sapiens BHF-UCL Protein disulfide-isomerase 20131115 UniProtKB P07237 P4HB part_of GO:0016222 procollagen-proline 4-dioxygenase complex cellular_component ECO:0000314 IDA PMID:7753822 9606 Homo sapiens MGI Protein disulfide-isomerase 20131115 UniProtKB P07237 P4HB involved_in GO:0034976 response to endoplasmic reticulum stress biological_process ECO:0000315 IMP PMID:12095988 9606 Homo sapiens BHF-UCL Protein disulfide-isomerase 20131115 UniProtKB P07237 P4HB involved_in GO:0071456 cellular response to hypoxia biological_process ECO:0000315 IMP PMID:12095988 9606 Homo sapiens BHF-UCL Protein disulfide-isomerase 20131115 UniProtKB P07237 P4HB located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19199708 9606 Homo sapiens UniProt Protein disulfide-isomerase 20131029 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:23152784 9606 Homo sapiens MGI Protein disulfide-isomerase 20130906 UniProtKB P07237 P4HB enables GO:0003756 protein disulfide isomerase activity molecular_function ECO:0000314 IDA PMID:15225124 9606 Homo sapiens CACAO Protein disulfide-isomerase 20120401 UniProtKB P07237 P4HB located_in GO:0005793 endoplasmic reticulum-Golgi intermediate compartment cellular_component ECO:0000314 IDA PMID:15308636 9606 Homo sapiens UniProt Protein disulfide-isomerase 20060116 UniProtKB P07237 P4HB acts_upstream_of_or_within GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline biological_process ECO:0000314 IDA PMID:7753822 9606 Homo sapiens MGI Protein disulfide-isomerase 20060111 UniProtKB P07237 P4HB located_in GO:0005576 extracellular region cellular_component ECO:0000303 NAS PMID:14718574 9606 Homo sapiens UniProt Protein disulfide-isomerase 20040422 UniProtKB P07237 P4HB enables GO:0003756 protein disulfide isomerase activity molecular_function ECO:0000304 TAS PMID:2846539 9606 Homo sapiens PINC Protein disulfide-isomerase 20030904 UniProtKB P07237 P4HB enables GO:0004656 procollagen-proline 4-dioxygenase activity molecular_function ECO:0000304 TAS PMID:2846539 9606 Homo sapiens PINC Protein disulfide-isomerase 20030904 UniProtKB P07237 P4HB located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000304 TAS PMID:3034602 9606 Homo sapiens PINC Protein disulfide-isomerase 20030904